[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100619692":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":10,"centralContacts":10,"locations":26,"responsibleParty":45,"collaborators":10,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":10,"eligibilityCriteria":55,"healthyVolunteers":51,"sex":56,"minAge":57,"maxAge":10,"enrollmentInfo":58,"targetDuration":10,"studyType":61,"phases":10,"briefSummary":62,"conditions":63,"keywords":65,"overallStatus":29,"whyStopped":10,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},{"fullName":5,"class":6},"Future University in Egypt","OTHER",[8,13],{"label":9,"type":10,"description":10,"interventionNames":11},"Prehospital ARNI users",null,[12],"Other: Prehospital ARNI use",{"label":14,"type":10,"description":10,"interventionNames":15},"Non-Prehospital ARNI users",[16],"Other: No prehospital ARNI use",[18,22],{"type":6,"name":19,"description":20,"armGroupLabels":21,"otherNames":10},"Prehospital ARNI use","Participants who were using ARNI therapy before hospital admission",[9],{"type":6,"name":23,"description":24,"armGroupLabels":25,"otherNames":10},"No prehospital ARNI use","Participants who were not using ARNI therapy before hospital admission",[14],[27],{"facility":28,"status":29,"city":30,"state":10,"zip":10,"country":31,"countryCode":32,"cosmosGeoPoint":33,"geoPoint":38,"contacts":39},"Mansoura university Hospital","RECRUITING","Al Mansurah","Egypt","EG",{"type":34,"coordinates":35},"Point",[36,37],31.38069,31.03637,{"lat":37,"lon":36},[40],{"name":41,"role":42,"phone":43,"phoneExt":10,"email":44},"Mansoura University Hospital","CONTACT","+201020296516","Hanaa.mm.abdelaziz@mans.edu.eg",{"type":46,"investigatorFullName":47,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Mrwan Ayman Ahmed Eassa","MS Student, Clinical Pharmacy Department, Future University in Egypt","100619692","effect-of-pre-hospital-arni-therapy-on-short-term-outcomes-in-hfref-100619692",false,"NCT07347925","Effect of Pre-Hospital ARNI Therapy on Short-Term Outcomes in HFrEF","Evaluating the Impact of Pre-Hospital Angiotensin Receptor-Neprilysin Inhibitor (ARNI) Therapy on Short-Term Clinical Outcomes in Heart Failure Patients With Reduced Ejection Fraction: A Comparative Study","Inclusion Criteria:\n\n* \\>= 18 years, male or female EF \\\u003C40%\n\nExclusion Criteria:\n\n* EF\\>40% Pregnancy or breastfeeding","ALL","18 Years",{"count":59,"type":60},140,"ESTIMATED","OBSERVATIONAL","This study looks at people with heart failure who are admitted to the hospital. The goal of the study is to understand whether taking a heart failure medicine called angiotensin receptor-neprilysin inhibitor (ARNI) before hospital admission affects short-term health outcomes.\n\nThe study will compare two groups of participants: those who were already taking ARNI before coming to the hospital and those who were not. Information will be collected from medical records during the hospital stay, including heart-related events, kidney-related events, and how long participants stay in the hospital.\n\nSome participants will also be followed for a short period after discharge. This study may help improve understanding of outcomes associated with ARNI use in people with heart failure in routine clinical care.",[64],"Heart Failure",[64,66,67,68],"NYHA class","Sacubitril\u002FValsartan","Chronic kidney disease","2026-01-11",{"date":71,"type":72},"2026-01-16","ACTUAL",{"date":74,"type":60},"2026-01-10",{"date":76,"type":60},"2026-05-01",{"name":5,"class":6},1]