[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100467282":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":40,"responsibleParty":57,"collaborators":26,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":26,"eligibilityCriteria":66,"healthyVolunteers":67,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":26,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":81,"overallStatus":83,"whyStopped":26,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Sun Yat-sen University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Highland barley β-glucan group","EXPERIMENTAL","Participants will be given oral liquids mainly containing highland barley β-glucan once daily for 12 weeks followed by comprehensive physical and clinical examinations.",[13],"Dietary Supplement: Highland barley β-glucan dietary supplement",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo group","PLACEBO_COMPARATOR","Participants will be given oral liquids mainly containing Corn starch once daily for 12 weeks followed by comprehensive physical and clinical examinations.",[19],"Other: Placebo controls",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DIETARY_SUPPLEMENT","Highland barley β-glucan dietary supplement","100 mL oral liquid mainly containing highland barley β-glucan once daily for 12 weeks",[9],null,{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Placebo controls","Placebo with a similar appearance and taste to highland barley β-glucan supplement",[15],[32],{"name":33,"affiliation":5,"role":34},"Min Xia, PhD","PRINCIPAL_INVESTIGATOR",[36],{"name":33,"role":37,"phone":38,"phoneExt":26,"email":39},"CONTACT","+86 20 87332433","xiamin@mail.sysu.edu.cn",[41],{"facility":42,"status":26,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Sun Yat-Sen University","Guangzhou","Guangdong","510080","China","CN",{"type":49,"coordinates":50},"Point",[51,52],113.25,23.11667,{"lat":52,"lon":51},[55],{"name":33,"role":37,"phone":56,"phoneExt":26,"email":39},"+86-2087332433",{"type":34,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Min Xia","Professor","100467282","effect-of-prebiotics-on-blood-pressure-management-100467282",false,"NCT05364736","Effect of Prebiotics on Blood Pressure Management","An Interventional Study for the Effects of Highland Barley β-glucan on the Management of Hypertension and Cardiovascular Risk","Inclusion Criteria:\n\n1. Age:30-65 years old\n2. Newly diagnosed hypertension did not use antihypertensive drugs OR Systolic blood pressure ≥140mmHg on the physical examination OR Diastolic blood pressure ≥90mmHg on the physical examination.\n3. BMI≥18 kg\u002Fm2\n\nExclusion Criteria:\n\n1. Receiving or have been treated with antihypertensive drugs.\n2. Complications including cardiovascular and cerebrovascular diseases such as coronary heart disease and stroke.\n3. Severe liver or renal insufficiency (alanine aminotransferase, aspartate aminotransferase or alkaline phosphatase is greater than 3 times the upper limit of normal OR GFR\\\u003C30ml\u002Fmin\u002F1.73m2).\n4. Autoimmune diseases or thyroid diseases.\n5. Women who are pregnant, nursing, or prepare to give birth during the trail.\n6. Malignant disease, infectious disease, inflammatory disease and advanced liver disease.\n7. Mental or intellectual abnormalities, unable to sign informed consent.\n8. Complications including chronic gastrointestinal disease; or suffered from acute gastrointestinal diseases within 1 months before screening visit.\n9. Received antibiotics, probiotics within 3 months before screening visit or throughout the trail.\n10. Major operations were performed within six months of screening visit, or will be made during the trial.\n11. Alcohol abuse (alcohol intake\\>60g\u002Fd for male and alcohol intake\\>40g\u002Fd for female)",true,"ALL","30 Years","65 Years",{"count":72,"type":73},100,"ESTIMATED","INTERVENTIONAL",[76],"NA","This survey is designed to investigate the effect of highland barley β-glucan supplementation on the regulatory of blood pressure, gut microbiota and cardiovascular risk fators in subjects with hypertention.",[79,80],"Hypertension","Gastrointestinal Microbiome",[79,80,82],"Prebiotics","NOT_YET_RECRUITING","2022-05-03",{"date":86,"type":87},"2022-05-06","ACTUAL",{"date":89,"type":73},"2022-10-17",{"date":91,"type":73},"2030-12-31",{"name":5,"class":6},1]