[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100644805":3},{"organization":4,"armGroups":7,"interventions":30,"overallOfficials":55,"centralContacts":59,"locations":66,"responsibleParty":83,"collaborators":64,"id":85,"slug":86,"hasResults":87,"nctId":88,"briefTitle":89,"officialTitle":90,"acronym":64,"eligibilityCriteria":91,"healthyVolunteers":87,"sex":92,"minAge":93,"maxAge":94,"enrollmentInfo":95,"targetDuration":64,"studyType":98,"phases":99,"briefSummary":101,"conditions":102,"keywords":64,"overallStatus":104,"whyStopped":64,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":113,"locationsCount":114},{"fullName":5,"class":6},"General Hospital of Ningxia Medical University","OTHER",[8,15,21,26],{"label":9,"type":10,"description":11,"interventionNames":12},"Group A1B1 (traditional conventional group)","ACTIVE_COMPARATOR","Pre-oxygenated left lateral position + examination in left lateral position",[13,14],"Procedure: Pre-oxygenation Position （left lateral position）","Procedure: Examination Position（left lateral position ）",{"label":16,"type":17,"description":18,"interventionNames":19},"Group A1B2 (improved examination group)","EXPERIMENTAL","Left lateral position with pre-oxygenation + left head elevated 30° during examination",[13,20],"Procedure: Examination Position（left lateral head elevation in a 30-degree position）",{"label":22,"type":17,"description":23,"interventionNames":24},"Group A2B1 (pre-oxygenation improvement group)","Left-sided head position at 30°, pre-oxygenated air administration + examination in left lateral decubitus position",[14,25],"Procedure: Pre-oxygenation Position（ left lateral head elevation in a 30-degree position）",{"label":27,"type":17,"description":28,"interventionNames":29},"Group A2B2 (double-position improvement group)","Left-sided head height at 30 weeks: pre-oxygenated condition + left-sided head height at 30 weeks examination",[25,20],[31,38,44,50],{"type":32,"name":33,"description":34,"armGroupLabels":35,"otherNames":36},"PROCEDURE","Pre-oxygenation Position （left lateral position）","An angle measuring device is placed beside the head of the examination bed to enable precise adjustment of the head position. Pre-oxygenation phase: Administer pure oxygen via a standardized mask with tight fit, at a flow rate of 6 L\u002Fmin; instruct the patient to take deep breaths while receiving continuous oxygen for 3 minutes, maintaining the same body position throughout. If the position is altered during this phase, discontinue the procedure. Left lateral pre-oxygenation: The patient assumes a left lateral position on a horizontal bed surface with the head elevated at 0°, supported by pillows to maintain a neutral spine position and avoid excessive neck extension or flexion.",[9,16],[37],"left lateral position",{"type":32,"name":39,"description":40,"armGroupLabels":41,"otherNames":42},"Examination Position（left lateral position ）","Examination Phase: From the initiation of anesthesia and endoscope insertion until completion of the procedure, the patient's position and head-of-bed angle must remain fixed throughout; any adjustments are prohibited during this phase. If the position is altered midway through the examination, the patient will be excluded from the study. Left lateral position examination: The patient assumes a 90-degree left lateral position on a horizontal bed surface with the head of the bed elevated to 0°, supported by pillows to maintain a neutral spinal alignment, avoiding excessive neck extension or flexion.",[9,22],[43],"Left lateral position",{"type":32,"name":45,"description":46,"armGroupLabels":47,"otherNames":48},"Pre-oxygenation Position（ left lateral head elevation in a 30-degree position）","An angle measuring device is placed beside the head of the examination bed to allow precise adjustment of the head position. Pre-oxygenation phase: The patient receives pure oxygen via a standardized mask with tight fit, at a flow rate of 6 L\u002Fmin; they are instructed to take deep breaths while receiving continuous oxygen for 3 minutes, maintaining the same body position throughout. If the position is altered during this phase, the procedure is discontinued. Left-sided head elevation (30°): During pre-oxygenation, the patient lies in a left lateral position on a horizontal bed surface with the head elevated by 30°, supported by pillows to maintain a neutral spinal alignment and prevent excessive neck extension or flexion.",[22,27],[49],"left lateral head elevation in a 30-degree position",{"type":32,"name":51,"description":52,"armGroupLabels":53,"otherNames":54},"Examination Position（left lateral head elevation in a 30-degree position）","Examination Phase: From the initiation of anesthesia and endoscope insertion until completion of the procedure, the patient's position and head-of-bed angle must remain fixed throughout; any adjustments are prohibited during this phase. If the position is altered midway through the examination, the patient will be excluded from the study. Left lateral decubitus examination: The patient assumes a left lateral position on a horizontal bed surface with the head elevated at 30°, supported by a pillow to maintain a neutral spinal alignment, avoiding excessive neck extension or flexion.",[16,27],[49],[56],{"name":57,"affiliation":5,"role":58},"Xinli Ni, Doctoral","STUDY_CHAIR",[60],{"name":61,"role":62,"phone":63,"phoneExt":64,"email":65},"xiaoyong wei, Master's degree","CONTACT","86-951-674-3252",null,"weixy9912@126.com",[67],{"facility":68,"status":64,"city":69,"state":70,"zip":71,"country":72,"countryCode":73,"cosmosGeoPoint":74,"geoPoint":79,"contacts":80},"General hospital of Ningxia medical university","Yinchuan","Ningxia","750001","China","CN",{"type":75,"coordinates":76},"Point",[77,78],106.27306,38.46806,{"lat":78,"lon":77},[81],{"name":61,"role":62,"phone":63,"phoneExt":64,"email":82},"weixy9912@126.cm",{"type":84,"investigatorFullName":64,"investigatorTitle":64,"investigatorAffiliation":64,"oldNameTitle":64,"oldOrganization":64},"SPONSOR","100644805","effect-of-preoxygenation-position-and-examination-position-on-hypoxemia-during-painless-gastrointestinal-endoscopy-100644805",false,"NCT07673042","Effect of Preoxygenation Position and Examination Position on Hypoxemia During Painless Gastrointestinal Endoscopy","Effect of Preoxygenation Position and Examination Position on Hypoxemia During Painless Gastrointestinal Endoscopy: A 2×2 Factorial Randomized Controlled Trial","Inclusion Criteria:\n\n* Aged 18 to 75 years, regardless of gender\n* Body mass index (BMI): 18.5 - 35 kg\u002Fm²\n* ASA physical status class I, II or III\n* Scheduled for painless gastroscopy, painless colonoscopy, or combined painless gastroenteroscopy\n* Able to understand the study procedure and provide written informed consent\n\nExclusion Criteria:\n\n* Severe cardiopulmonary diseases, including severe COPD, heart failure, severe arrhythmia and pulmonary hypertension\n* Difficult airway identified before anesthesia\n* Severe obstructive sleep apnea (OSA)\n* Spinal or thoracic deformity\n* Preoperative baseline hypoxemia\n* Known allergy to any anesthetic drugs used in this study\n* Pregnant females\n* Unable to cooperate with required intraoperative body position","ALL","18 Years","75 Years",{"count":96,"type":97},208,"ESTIMATED","INTERVENTIONAL",[100],"NA","To investigate the independent effects and interaction of pre-oxygenation position (left lateral vs left lateral with 30° head-up tilt) and examination position (left lateral vs left lateral with 30° head-up tilt) on hypoxemia during painless gastroscopy and colonoscopy using a 2×2 factorial design.",[103],"Hypoxemia During Surgery","NOT_YET_RECRUITING","2026-06-24",{"date":107,"type":108},"2026-06-29","ACTUAL",{"date":110,"type":97},"2026-06-23",{"date":112,"type":97},"2026-08-31",{"name":5,"class":6},1]