[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100635288":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":11,"centralContacts":23,"locations":29,"responsibleParty":44,"collaborators":48,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":11,"eligibilityCriteria":57,"healthyVolunteers":58,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":11,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":11,"overallStatus":32,"whyStopped":11,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"Assiut University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Volume controlled ventilation ( VCV )","EXPERIMENTAL",null,[13],"Diagnostic Test: electrical cardiometry ('ICON CARDIOTRONIC, OSYPKA MEDICAL') , Lung ultrasonography (LUS) for atelectasis",{"label":15,"type":10,"description":11,"interventionNames":16},"Pressure-controlled ventilation-volume guaranteed (PCV-VG)",[13],[18],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":11},"DIAGNOSTIC_TEST","electrical cardiometry ('ICON CARDIOTRONIC, OSYPKA MEDICAL') , Lung ultrasonography (LUS) for atelectasis","electrical cardiometry estimates cardiac parameters by measuring changes in thoracic electrical bioimpedance during the cardiac cycle. The ICON, using four electrocardiogram (ECG) electrodes, estimates the maximum rate of change of impedance to peak aortic blood acceleration based on the principle that red blood cells change from random orientation during diastole (high impedance) to an aligned state during systole (low impedance). This device estimates CO, cardiac index (CI), stroke volume (SV), systemic vascular resistance (SVR), and a variety of other cardiac parameters ... Lung ultrasonography (LUS) in patients who are under anesthesia and scheduled for surgery can detect intraoperative atelectasis, and the LUS score is correlated with perioperative oxygenation impairment",[15,9],[24],{"name":25,"role":26,"phone":27,"phoneExt":11,"email":28},"Saif eldeen Gamal Khalaf, Assistant lecturer","CONTACT","+20-1033893202","saifeldeen616@gmail.com",[30],{"facility":31,"status":32,"city":33,"state":11,"zip":11,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"South Egypt cancer institute , Assiut university","RECRUITING","Asyut","Egypt","EG",{"type":37,"coordinates":38},"Point",[39,40],31.18368,27.18096,{"lat":40,"lon":39},[43],{"name":25,"role":26,"phone":27,"phoneExt":11,"email":28},{"type":45,"investigatorFullName":46,"investigatorTitle":47,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Saif Eldeen Gamal Khalaf","Assistant lecturer",[49],{"name":50,"class":6},"South Egypt Cancer Institute","100635288","effect-of-pressure-controlled-volume-guaranteed-versus-volume-controlled-ventilation-modes-on-hemodynamic-outcomes-eg--sv-co--and-respiratory-mechanics-during-laparoscopic-abdominal-cancer-surgeries-with-exaggerated-trendelenberg-postion-100635288",false,"NCT07550738","Effect of Pressure-Controlled Volume Guaranteed Versus Volume-Controlled Ventilation Modes on Hemodynamic Outcomes e.g ( SV, CO ) and Respiratory Mechanics During Laparoscopic Abdominal Cancer Surgeries With Exaggerated Trendelenberg Postion","Effect of Pressure-Controlled Volume Guaranteed Versus Volume-Controlled Ventilation Modes on Hemodynamic Outcomes and Respiratory Mechanics During Laparoscopic Abdominal Cancer Surgeries With Exaggerated Trendelenberg Postion : A Randomized Controlled Trial","Inclusion Criteria:\n\n1 - All patients who will be scheduled for elective laparoscopic abdominal cancer surgeries 2- patients aged 20-80 years 3- patients have an American Society of Anesthesiologists (ASA) physical status I-II\n\nExclusion Criteria:\n\n1 - Patients with severe systemic disease (history of myocardial infarction, chronic obstructive, or restrictive lung disease) 2- Obese patients (BMI \\> 30) 3- patients with neurologic or neuromuscular diseases.",true,"ALL","20 Years","80 Years",{"count":63,"type":64},60,"ESTIMATED","INTERVENTIONAL",[67],"NA","The primary outcome is to compare the hemodynamic outcomes ( e.g SV , CO and CI ) using The ICON of two different modes of ventilation ( VCV and PC-VG ) during laparoscopic abdominal cancer surgeries with exaggerated trendelenburg position.\n\nAnd the secondary outcomes is to compare the respiratory effects ( e.g atelectasis development , plateau pressure(Pplat) , peak inspiratory pressure(PIP) , dyn. compliance and postoperative inflammatory indicators e.g CRP and WBCs ) of two different modes of ventilation ( VCV and PC-VG ) during laparoscopic abdominal cancer surgeries with exaggerated trendelenburg position.",[70],"PCV-VG Versus VCV Ventilation Mode Effects on Hemodynamics","2026-07-01",{"date":73,"type":74},"2026-07-02","ACTUAL",{"date":76,"type":74},"2026-04-01",{"date":78,"type":64},"2027-06",{"name":5,"class":6},1]