[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100548836":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":37,"locations":45,"responsibleParty":58,"collaborators":61,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":25,"eligibilityCriteria":71,"healthyVolunteers":67,"sex":72,"minAge":73,"maxAge":74,"enrollmentInfo":75,"targetDuration":25,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":85,"overallStatus":47,"whyStopped":25,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"University of Sao Paulo General Hospital","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Resistance Training Group","EXPERIMENTAL","Patients will receive the standard treatment provided by the hospital inpatient unit alongside the resistance training program.",[13,14],"Other: Resistance Training Program","Other: Standard Treatment Group",{"label":16,"type":17,"description":18,"interventionNames":19},"Standard Treatment Group","ACTIVE_COMPARATOR","Patients will receive the standard treatment provided by the hospital inpatient unit.",[14],[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Resistance Training Program","The resistance training program will be individualized and divided into four stages of increasing complexity. It will be conducted for approximately 40 minutes per day, three times a week, for 12 weeks, under supervision. Each patient will begin the program at the stage corresponding to their functional capacity. The resistance load will be set at 50% of the maximum resistance (1RM) obtained in the initial assessment. Throughout all stages of the exercise program, the target intensity will range from light (≤ 12) to moderate (≤ 15) on the Borg scale.",[9],null,{"type":6,"name":16,"description":27,"armGroupLabels":28,"otherNames":25},"Patients will receive the standard treatment provided by the hospital inpatient unit, which includes guidance on reducing sedentary time, encouragement to walk, and performance of active and breathing exercises when necessary.",[9,16],[30,34],{"name":31,"affiliation":32,"role":33},"Juliana A Nascimento, PT, PhD","University of Sao Paulo","PRINCIPAL_INVESTIGATOR",{"name":35,"affiliation":36,"role":33},"Rafael M Ianotti, PT","Instituto do Coração - Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo",[38,42],{"name":31,"role":39,"phone":40,"phoneExt":25,"email":41},"CONTACT","+55 11 30618529","juliana.nascimento@fm.usp.br",{"name":35,"role":39,"phone":43,"phoneExt":25,"email":44},"+55 11 26615319","rafael.ianotti@hc.fm.usp.br",[46],{"facility":36,"status":47,"city":48,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":25},"RECRUITING","São Paulo","05403-000","Brazil","BR",{"type":53,"coordinates":54},"Point",[55,56],-46.63611,-23.5475,{"lat":56,"lon":55},{"type":33,"investigatorFullName":59,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Rafael M. Ianotti, P.T., Ph.D.","Clinical Research Coordinator - Physiotherapy Division - Heart Institute (InCor)",[62],{"name":63,"class":64},"Conselho Nacional de Desenvolvimento Científico e Tecnológico","OTHER_GOV","100548836","effect-of-resistance-training-in-patients-on-the-waiting-list-for-heart-transplant-100548836",false,"NCT06426173","Effect of Resistance Training in Patients on the Waiting List for Heart Transplant","Effect of Resistance Training on Functional Capacity, Quality of Life and Cardiac Biomarkers in Patients on the Waiting List for Heart Transplant: a Randomized and Controlled Clinical Trial","Inclusion Criteria:\n\n* patients included in heart transplant list ≤1 month\n* hemodynamically stable in the last 48 hours defined as mean arterial pressure (MAP) ≥ 60 mmHg and ≤ 120 mmHg and - Heart rate (HR) ≥ 60 bpm and ≤ 120 mmHg.\n* dobutamine dose ≤ 10 mcg\u002Fkg\u002Fmin\n\nExclusion Criteria:\n\n* heart failure of arrhythmogenic and\u002For restrictive etiology\n* presence of uncontrolled acute arrhythmias\n* cognitive, orthopedic, or neuromotor changes that prevent functional tests from being carried out","ALL","18 Years","70 Years",{"count":76,"type":77},50,"ESTIMATED","INTERVENTIONAL",[80],"NA","The present longitudinal, randomized, and blinded clinical trial aims to:\n\n* Evaluate the effects of resistance training on the functional capacity, quality of life, and cardiac biomarkers of hospitalized patients with heart failure (HF) on the waiting list for heart transplantation (HTx).\n* Evaluate the associations between Fried's frailty classification and functional capacity responses to resistance training.\n\nThe protocol will have a total duration of 12 weeks.",[83,84],"Heart Failure","Heart Transplant",[86,87,88],"heart failure","resistance training","cardiac rehabilitation","2026-06-18",{"date":91,"type":92},"2026-06-22","ACTUAL",{"date":94,"type":92},"2024-06-18",{"date":96,"type":77},"2027-06-30",{"name":5,"class":6},1]