[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100598963":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":38,"centralContacts":42,"locations":29,"responsibleParty":47,"collaborators":29,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":52,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":29,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":72,"overallStatus":77,"whyStopped":29,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":29},{"fullName":5,"class":6},"Sakarya Applied Sciences University","OTHER",[8,16,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Group I: Pelvic floor rehabilitation","EXPERIMENTAL","Pelvic floor rehabilitation only",[13,14,15],"Other: Pelvic floor rehabilitation","Other: Diaphragmatic Breathing Exercises","Other: Diaphragm Manual Therapy",{"label":17,"type":10,"description":18,"interventionNames":19},"Group II: Pelvic floor rehabilitation + diaphragmatic breathing exercises","Pelvic floor rehabilitation + diaphragmatic breathing exercises",[14,15],{"label":21,"type":10,"description":22,"interventionNames":23},"Group III: Pelvic floor rehabilitation + diaphragmatic breathing exercises + diaphragm manual therap","Pelvic floor rehabilitation + diaphragmatic breathing exercises + diaphragm manual therapy",[15],[25,30,34],{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":29},"Pelvic floor rehabilitation","Participants in this group will receive standard pelvic floor rehabilitation. This includes education about pelvic floor anatomy and function, supervised pelvic floor muscle training (Kegel exercises), relaxation techniques, and manual release of trigger points if necessary. The aim is to improve muscle strength, coordination, and reduce pelvic floor hypertonicity contributing to dyspareunia.",[9],null,{"type":6,"name":31,"description":32,"armGroupLabels":33,"otherNames":29},"Diaphragmatic Breathing Exercises","In addition to the standard pelvic floor rehabilitation, participants in this group will practice diaphragmatic breathing exercises. These exercises focus on deep, slow nasal inhalation using the diaphragm, encouraging abdominal expansion while minimizing chest movement. Sessions are performed twice daily for 10 minutes. This technique is aimed at promoting parasympathetic activation, reducing anxiety, and improving autonomic regulation.",[9,17],{"type":6,"name":35,"description":36,"armGroupLabels":37,"otherNames":29},"Diaphragm Manual Therapy","an additional manual therapy intervention targeting the diaphragm. Diaphragm manual therapy involves hands-on techniques applied to the thoracic and abdominal regions to reduce fascial restrictions, improve diaphragmatic mobility, and support deeper, more effective breathing. The therapy is delivered for 15 minutes at the start of each weekly session by a trained physiotherapist.",[9,17,21],[39],{"name":40,"affiliation":5,"role":41},"Abdurrahim Yıldız, Assoc. Prof.","PRINCIPAL_INVESTIGATOR",[43],{"name":40,"role":44,"phone":45,"phoneExt":29,"email":46},"CONTACT","+905077516363","abdurrahimyildiz@subu.edu.tr",{"type":41,"investigatorFullName":48,"investigatorTitle":49,"investigatorAffiliation":5,"oldNameTitle":29,"oldOrganization":29},"Abdurrahim Yıldız","Assoc. Prof.","100598963","effect-of-respiratory-exercises-with-pelvic-floor-rehab-on-dyspareunia--autonomic-function-in-women-100598963",false,"NCT07078318","Effect of Respiratory Exercises With Pelvic Floor Rehab on Dyspareunia & Autonomic Function in Women","The Effect of Respiratory Exercises Given in Addition to Pelvic Floor Rehabilitation on Dyspareunia and Autonomic Nervous System in Women With Musculoskeletal Dyspareunia","Dyspareunia","Inclusion Criteria:\n\nFemale participants aged between 18 and 45 years\n\nExperiencing dyspareunia of musculoskeletal origin for at least 6 months\n\nIn a stable sexual relationship and sexually active\n\nWilling and able to attend weekly treatment sessions for 8 weeks\n\nAble to provide informed consent\n\nNo pelvic surgery within the last 6 months\n\nNormal cognitive function and ability to follow instructions\n\nBaseline FSFI score indicating sexual dysfunction (e.g., ≤ 26.55)\n\nExclusion Criteria:\n\n* Presence of neurological, gynecological, or urological pathologies causing pelvic pain (e.g., endometriosis, pelvic inflammatory disease)\n\nPregnancy or postpartum period within the last 6 months\n\nDiagnosed psychiatric disorders (e.g., major depression, psychosis)\n\nUse of medications that affect autonomic nervous system function (e.g., beta-blockers, antidepressants)\n\nHistory of pelvic radiation, cancer, or pelvic trauma\n\nParticipation in other rehabilitation or psychotherapy programs during the study period\n\nInability to tolerate manual therapy or perform breathing exercises\n\nBMI \\> 35, which may interfere with ultrasonographic assessment\n\nNon-compliance risk, such as irregular attendance or language barriers","FEMALE","18 Years","45 Years",{"count":62,"type":63},45,"ESTIMATED","INTERVENTIONAL",[66],"NA","Background and Aim:\n\nDyspareunia, or pain during sexual intercourse, is a common component of female sexual dysfunction and may have multifactorial origins, including musculoskeletal and autonomic factors. While pelvic floor rehabilitation is an established treatment approach for musculoskeletal dyspareunia, it may not sufficiently address the autonomic dysregulation commonly observed in chronic pain conditions. The aim of this study is to investigate the effects of adding diaphragmatic breathing exercises and diaphragm manual therapy to standard pelvic floor rehabilitation on pain severity, pelvic floor function, and autonomic nervous system regulation in women diagnosed with musculoskeletal-origin dyspareunia.\n\nMethods:\n\nThis randomized controlled clinical trial will be conducted between September 1, 2025, and December 1, 2025, at the Kurbaa Training and Consultation Center in Istanbul. A total of 45 participants aged 18-45 years who meet the inclusion criteria will be randomly assigned into three equal groups (n = 15):\n\nGroup I: Pelvic floor rehabilitation only\n\nGroup II: Pelvic floor rehabilitation + diaphragmatic breathing exercises\n\nGroup III: Pelvic floor rehabilitation + diaphragmatic breathing exercises + diaphragm manual therapy\n\nInterventions will be administered once per week for 8 weeks. Pre- and post-intervention assessments will include pain intensity (Visual Analog Scale), pelvic floor muscle function (ultrasonography), sexual function (Female Sexual Function Index), anxiety level (Beck Anxiety Inventory), and autonomic regulation (Heart Rate Variability using Elite HRV). Statistical analyses will be performed using SPSS with significance set at p \\\u003C 0.05.\n\nExpected Contribution:\n\nThis study is expected to contribute to the development of more comprehensive treatment protocols for dyspareunia by integrating physical and neurophysiological rehabilitation components. It may also provide evidence supporting the role of autonomic regulation in improving treatment outcomes for female sexual pain disorders.",[69,70,71],"Dyspareunia (Female Excluding Psychogenic)","Female Sexual Dysfunction (FSD)","Chronic Pelvic Pain",[56,73,74,75,76],"Pelvic Floor Rehab","Manual Therapy","Autonomic Regulation","Sexual Dysfunction","NOT_YET_RECRUITING","2025-07-13",{"date":80,"type":81},"2025-07-22","ACTUAL",{"date":83,"type":63},"2025-09-01",{"date":85,"type":63},"2026-12-01",{"name":5,"class":6}]