[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100631127":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":26,"responsibleParty":40,"collaborators":26,"id":44,"slug":45,"hasResults":46,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":26,"eligibilityCriteria":50,"healthyVolunteers":46,"sex":51,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":26,"studyType":57,"phases":58,"briefSummary":60,"conditions":61,"keywords":63,"overallStatus":67,"whyStopped":26,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":26},{"fullName":5,"class":6},"Bangladesh Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group Surgical site infiltration (SSI)","ACTIVE_COMPARATOR","Participants in this group will receive standard general anesthesia for elective supratentorial craniotomy. In addition, local anesthetic will be administered via surgical site infiltration.",[13],"Procedure: Surgical site infiltration with plain bupivacaine",{"label":15,"type":16,"description":17,"interventionNames":18},"Group Scalp block","EXPERIMENTAL","Participants in this group will receive standard general anesthesia for elective supratentorial craniotomy. In addition, they will receive an ultrasound-guided scalp block targeting the major nerves of the scalp.",[19],"Procedure: Scalp block with plain bupivacaine",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Surgical site infiltration with plain bupivacaine","Participants receiving this intervention will undergo local anesthetic infiltration at the planned surgical sites in addition to standard general anesthesia for elective supratentorial craniotomy.\n\nDrug: Bupivacaine 0.5% plain solution\n\nDosage: 10-15 ml along the incision line plus 5 ml at each pin insertion site\n\nDosage Form: Injectable solution\n\nRoute: Subcutaneous and deep infiltration into the scalp\n\nTiming: Single administration immediately after induction of general anesthesia, prior to surgical incision",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Scalp block with plain bupivacaine","Participants receiving this intervention will undergo ultrasound-guided regional nerve blockade of the scalp in addition to standard general anesthesia for elective supratentorial craniotomy. The procedure targets the supratrochlear, supraorbital, auriculotemporal, postauricular branches of the greater auricular nerve, and the greater, lesser, and third occipital nerves.",[15],[32,37],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Kazi Mahzabin Arin, MD","CONTACT","+8801754057689","kazimahzabinarin@bsmmu.edu.bd",{"name":38,"role":34,"phone":26,"phoneExt":26,"email":39},"AKM Akhtaruzzaman, MD","akm.akhtaruzzaman@bmu.ac.bd",{"type":41,"investigatorFullName":42,"investigatorTitle":43,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Kazi Mahzabin Arin","Assistant Professor","100631127","effect-of-scalp-block-on-intraoperative-hemodynamics-and-postoperative-pain-in-craniotomy-patients-100631127",false,"NCT07496632","Effect of Scalp Block on Intraoperative Hemodynamics and Postoperative Pain in Craniotomy Patients\"","Efficacy of Scalp Block on Intraoperative Hemodynamic Responses and Postoperative Analgesia in Patients Undergoing Craniotomy","Inclusion Criteria:\n\n* Age 18-64 years.\n* ASA (American Society of Anesthesiologists) physical status I or II.\n* Patients scheduled for elective supratentorial craniotomy.\n* BMI of 18 to 30 kg\u002Fm².\n* GCS score of 9 to 15.\n\nExclusion Criteria:\n\n* Patient with instable blood pressure and heart rate.\n* Known allergy or hypersensitivity to local anesthetics.\n* Coagulation disorders or current anticoagulant therapy.\n* Infection at the injection site or systemic infection.\n* Patients with open skull defects.","ALL","18 Years","64 Years",{"count":55,"type":56},72,"ESTIMATED","INTERVENTIONAL",[59],"NA","The goal of this clinical trial is to learn if an ultrasound-guided scalp block can improve intraoperative hemodynamic stability and provide better postoperative pain relief in adult patients undergoing elective supratentorial craniotomy. The main questions it aims to answer are:\n\nDoes ultrasound-guided scalp block reduce changes in heart rate and blood pressure during surgery compared with surgical site infiltration?\n\nDoes ultrasound-guided scalp block decrease postoperative pain and opioid requirements in the first 24 hours after craniotomy?\n\nResearchers will compare patients receiving an ultrasound-guided scalp block to those receiving standard surgical site infiltration to see if the scalp block provides better perioperative hemodynamic control and postoperative analgesia.\n\nParticipants will:\n\nReceive general anesthesia with either ultrasound-guided scalp block or surgical site infiltration\n\nHave heart rate, blood pressure, and other hemodynamic parameters monitored throughout surgery\n\nReceive standard postoperative pain management, with pain scores recorded at 0, 2, 6, 12, and 24 hours\n\nReceive opioids as needed based on pain scores, with total opioid consumption and time to first analgesic dose recorded\n\nBe monitored for adverse events, including nausea, vomiting, sedation, and block-related complications",[62],"Scalp Block",[62,64,65,66],"Intraoperative Hemodynamic Responses","Postoperative Analgesia","Craniotomy","NOT_YET_RECRUITING","2026-03-27",{"date":70,"type":71},"2026-04-01","ACTUAL",{"date":73,"type":56},"2026-04",{"date":75,"type":56},"2026-10",{"name":5,"class":6}]