[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100529981":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":12,"centralContacts":25,"locations":31,"responsibleParty":51,"collaborators":12,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":12,"eligibilityCriteria":60,"healthyVolunteers":61,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":12,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":82,"overallStatus":34,"whyStopped":12,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"University of Utah","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Control Group","NO_INTERVENTION","Provided with general health information on diet and physical activity.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Intervention Group","EXPERIMENTAL","Sleep extension-based intervention focused on increasing time in bed by 2 hours per night.",[18],"Behavioral: Sleep Extension Intervention",[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":12},"BEHAVIORAL","Sleep Extension Intervention","Sleep extension-based intervention focused on increasing time spent in bed by 2 hours per night by directly scheduling assigned bed and waketimes based on participant's individual schedules. Participants will receive weekly sleep tips and counseling on improving their sleep duration.",[14],[26],{"name":27,"role":28,"phone":29,"phoneExt":12,"email":30},"Christopher M Depner, PhD","CONTACT","801-581-2275","christopher.depner@utah.edu",[32],{"facility":33,"status":34,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"College of Health Research Complex--University of Utah","RECRUITING","Salt Lake City","Utah","84112","United States","US",{"type":41,"coordinates":42},"Point",[43,44],-111.89105,40.76078,{"lat":44,"lon":43},[47],{"name":48,"role":28,"phone":49,"phoneExt":12,"email":50},"Christopher Depner","8015812275","sleepstudyparticipant@utah.edu",{"type":52,"investigatorFullName":48,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"PRINCIPAL_INVESTIGATOR","Assistant Professor","100529981","effect-of-sleep-extension-on-ceramides-in-people-with-overweight-and-obesity-100529981",false,"NCT06180837","Effect of Sleep Extension on Ceramides in People with Overweight and Obesity","Biomarkers of Habitual Short Sleep and Related Cardiometabolic Risk","Inclusion Criteria:\n\n1. Age: 18-45 years old; equal numbers of men and women\n2. Body mass index (BMI): 27.5-34.9 kg\u002Fm2\n3. Sleep Habits: habitual self-reported average total sleep time (TST) \\\u003C6.5 hours per night for prior 6 months\n\nExclusion Criteria:\n\n1. Clinically diagnosed sleep disorder or major psychiatric illness\n2. Evidence of significant organ dysfunction or disease (e.g., heart disease, kidney disease)\n3. Clinically diagnosed diabetes or fasting plasma glucose ≥126 mg\u002FdL or HbA1c ≥6.5%\n4. Use of prescription drugs or substances known to influence sleep or glucose metabolism, or anticoagulant medications.\n5. Cancer that has been in remission less than 5 years\n6. Pregnant\u002Fnursing, experiencing menopause or post-menopausal\n7. Shift-work: current or history of within last year\n8. Weight change: \\>10% of body weight over prior six months\n9. Current enrollment in weight loss or physical activity program like the Diabetes Prevention Program\n10. Currently smoking\n11. Alcohol intake\\>14 drinks per week or \\>3 drinks per day",true,"ALL","18 Years","45 Years",{"count":66,"type":67},70,"ESTIMATED","INTERVENTIONAL",[70],"NA","The overall goal is to determine how a sleep extension intervention (increasing time in bed) in individuals who maintain less than 6.5 hours sleep per night affects their plasma ceramides and insulin sensitivity. Participants will undergo a randomized controlled trial, with sleep extension (intervention) and healthy lifestyle (control) groups. The sleep extension is designed to increase participant's time in bed by 2 hours per night. Alternatively, the control group will receive basic health information (e.g., physical activity, goal setting, and nutrition when eating out).",[73,74,75,76,77,78,79,80,81],"Lifestyle Factors","Overweight and Obesity","Insulin Sensitivity","Eating Habit","Sleep Hygiene","Type 2 Diabetes","Sleep","Sleep Deprivation","Insufficient Sleep Syndrome",[83,84],"sleep","insulin sensitivity","2024-12-18",{"date":87,"type":88},"2024-12-20","ACTUAL",{"date":90,"type":88},"2024-02-12",{"date":92,"type":67},"2028-01",{"name":5,"class":6},1]