[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100627742":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":26,"responsibleParty":40,"collaborators":26,"id":44,"slug":45,"hasResults":46,"nctId":47,"briefTitle":48,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":46,"sex":51,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":26,"studyType":57,"phases":58,"briefSummary":60,"conditions":61,"keywords":65,"overallStatus":68,"whyStopped":26,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":26},{"fullName":5,"class":6},"Sohag University","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention group","EXPERIMENTAL","treatment of microbial keratitis by antibiotic with sodium chloride 5%",[13,14],"Drug: Sodium chloride 5% solution","Drug: quinolones",{"label":16,"type":17,"description":18,"interventionNames":19},"Control group","ACTIVE_COMPARATOR","Treatment of microbial keratitis by antibiotics only",[14],[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Sodium chloride 5% solution","Use Sodium chloride 5% solution with usual anti microbial drugs",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"quinolones","Use of usual topical anti microbial treatment only",[16,9],[32,37],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Nancy Safwat Kaldas, Specialist","CONTACT","01200933440","nansy_safwat_post@med.sohag.edu.eg",{"name":38,"role":34,"phone":39,"phoneExt":26,"email":26},"Amr Mounir Mohamed, Assistant professor","01005026170",{"type":41,"investigatorFullName":42,"investigatorTitle":43,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Nancy Safwat Kaldes","Principal Investigator","100627742","effect-of-sodium-chloride-5-solution-as-an-adjuvant-treatment-with-antimicrobial-therapy-in-the-treatment-of-bacterial-infectious-keratitis-100627742",false,"NCT07452588","Effect of Sodium Chloride 5% Solution as an Adjuvant Treatment With Antimicrobial Therapy in the Treatment of Bacterial Infectious Keratitis","keratitis","IncluInclusion Criteria\n\n* Age ≥ 18 years.\n* Clinically diagnosed bacterial infectious keratitis\n* Positive corneal scraping or strong clinical suspicion of bacterial cause.\n* Ability to provide informed consent and attend follow-up visits\n\nExclusion Criteria:\n\n* • Fungal, viral, or acanthamoeba keratitis.\n\n  * Recent (\\\u003C7 days) topical corticosteroid use.\n  * Corneal perforation or impending perforation.\n  * History of hypersensitivity to study agents.\n  * Systemic immunocompromised state (uncontrolled diabetes, Human immune defecinicy virus).\n  * Poor compliance expected with follow-up.","ALL","18 Years","60 Years",{"count":55,"type":56},40,"ESTIMATED","INTERVENTIONAL",[59],"NA","This study aims to detect the effect of sodium chloride 5% solution as an adjuvant treatment with antimicrobial therapy in treatment of bacterial infectious keratits and to assess whether NaCl 5% accelerates epithelial healing, improves microbial eradication, and enhances visual outcomes in bacterial infectious keratitis.",[62,63,64],"Infectious Keratitis","Adjuvant Treatment Bacterial Infectious Keratitis","Sodium Chloride 5% Solution",[66,67],"Bacterial infectious keratitis","Sodiunchloride5%","NOT_YET_RECRUITING","2026-03-02",{"date":71,"type":72},"2026-03-05","ACTUAL",{"date":74,"type":56},"2026-02",{"date":76,"type":56},"2027-02",{"name":5,"class":6}]