[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100492167":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":11,"centralContacts":29,"locations":39,"responsibleParty":56,"collaborators":11,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":64,"acronym":11,"eligibilityCriteria":65,"healthyVolunteers":66,"sex":67,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":11,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":11,"overallStatus":42,"whyStopped":11,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Anahuac University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental group","ACTIVE_COMPARATOR",null,[13],"Dietary Supplement: Enteroccocus Facieum and Agave Inulin",{"label":15,"type":16,"description":11,"interventionNames":17},"Control group","PLACEBO_COMPARATOR",[18],"Other: Placebo",[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":11},"DIETARY_SUPPLEMENT","Enteroccocus Facieum and Agave Inulin","A pack of symbiotic powder with 1 gram of e. facieum and 8g of agave inulin will be administered daily for 8 weeks",[9],{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":11},"Placebo","A pack of unsweetened almond powder milk will be administered daily for 8 weeks",[15],[30,35],{"name":31,"role":32,"phone":33,"phoneExt":11,"email":34},"JOSE JUAN ANTONIO IBARRA ARIAS, MEDICO CIRUJANO","CONTACT","5554197603","jose.ibarra@anahuac.mx",{"name":36,"role":32,"phone":37,"phoneExt":11,"email":38},"ADELA ESCANDON CESARMAN, MEDICO CIRUJANO","5520459938","adela.escandon.cesarman@gmail.com",[40],{"facility":41,"status":42,"city":43,"state":11,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Hospital ABC Santa Fe","RECRUITING","Mexico City","05300","Mexico","MX",{"type":48,"coordinates":49},"Point",[50,51],-99.12766,19.42847,{"lat":51,"lon":50},[54],{"name":55,"role":32,"phone":37,"phoneExt":11,"email":38},"Adela Escandon-Cesarman, Medical degree",{"type":57,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Jose Juan Antonio Ibarra Arias","Responsable","100492167","effect-of-the-administration-of-a-symbiotic-e-faecium-and-agave-inulin-on-mild-cognitive-impairment-in-older-adults-100492167",false,"NCT05688618","Effect of the Administration of a Symbiotic (E. Faecium and Agave Inulin) on Mild Cognitive Impairment in Older Adults","Inclusion Criteria:\n\n* Patients with mild cognitive impairment\n* Patients who sign the informed consent\n\nExclusion Criteria:\n\n* Patients who do not have mild cognitive impairment\n* Patients with advanced cognitive impairment such as Alzheimers disease\n* Patients with comorbidities that influence the cognitive functions such as diabetes mellitus, cerebral ischemia or previous brain trauma\n* Patients who do not sign the informed consent",true,"ALL","70 Years","85 Years",{"count":71,"type":72},48,"ESTIMATED","INTERVENTIONAL",[75],"NA","Cognitive impairment is one of the fastest growing diseases in the last decades, given the significant increase in senior citizen population in Mexico and the world.\n\nSeveral studies have discussed the gut-microbiota-brain axis. It has been demonstrated that a balanced gut microbiota, prevents an increase in pro-inflammatory cytokines that affect specific brain areas; having an important impact at the cortical level of the hippocampus which translates to diminished cognitive function and the start of cognitive impairment symptoms.\n\nAfter multiple studies on the effect of the administration of symbiotics in animal models in cognition and memory, there have been positive results, observing improvement in cognition and decrement in inflammatory cytokines at hippocampus level.",[78],"Cognitive Impairment","2024-07-29",{"date":81,"type":82},"2024-07-30","ACTUAL",{"date":84,"type":82},"2022-11-16",{"date":86,"type":72},"2024-10-20",{"name":5,"class":6},1]