[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100591097":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":26,"centralContacts":30,"locations":35,"responsibleParty":58,"collaborators":25,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":25,"eligibilityCriteria":66,"healthyVolunteers":62,"sex":67,"minAge":68,"maxAge":25,"enrollmentInfo":69,"targetDuration":25,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":25,"overallStatus":38,"whyStopped":25,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Peking University First Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention group","ACTIVE_COMPARATOR","The intervention group will receive oral postbiotics product for 150ml per day during the treatment period (from week 1 to week 12). Then, the group will end the trial.",[13],"Dietary Supplement: Yi'en Yuan Honey Fermented Drink",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo group","PLACEBO_COMPARATOR","The placebo group will receive oral placebo during the treatment period (from week 1 to week 12). Then, the group will enter into remedial the treatment period (from week 13 to week 24) and receive the same oral postbiotics product as intervention group for 150ml per day. The group will end the trial at week 24.",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DIETARY_SUPPLEMENT","Yi'en Yuan Honey Fermented Drink","The oral postbiotics product used in the trial is called Yi'en Yuan Honey Fermented Drink. The product is made from water, edible brown sugar, and honey as raw materials. It is fermented by a mixture of plant lactic acid bacteria and coagulating Bacillus, and then inactivated at high temperature. The product meets the food and beverage standard. Participants will receive the product for 150ml per day.",[9,15],null,[27],{"name":28,"affiliation":5,"role":29},"Yuqing Chen","STUDY_CHAIR",[31],{"name":28,"role":32,"phone":33,"phoneExt":25,"email":34},"CONTACT","86-010-82572254","cyq@bjmu.edu.cn",[36],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Peking UFH","RECRUITING","Beijing","Beijing Municipality","100034","China","CN",{"type":45,"coordinates":46},"Point",[47,48],116.39723,39.9075,{"lat":48,"lon":47},[51,54],{"name":52,"role":32,"phone":53,"phoneExt":25,"email":34},"Yuqing Chen, PhD","15910285602",{"name":55,"role":32,"phone":56,"phoneExt":25,"email":57},"Di Song, PhD","15201303625","hellosongdi@163.com",{"type":59,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100591097","effect-of-the-postbiotics-on-complications-treatment-in-elderly-hemodialysis-patients-100591097",false,"NCT06975995","Effect of the Postbiotics on Complications Treatment in Elderly Hemodialysis Patients","A Postbiotics Improves the Quality of Life and Nutritional Status in Elderly Hemodialysis Patients","Inclusion Criteria:\n\nInvestigators must maintain a screening log of all potential study candidates that includes limited information about the potential candidate, date, and outcome of the screening process (e.g. enrolled into study, reason for ineligibility, or refused to participate). After signing an informed consent form, potential patients must meet all of the criteria:\n\n1. Age ≥65 years.\n2. Receiving maintenance hemodialysis therapy for at least 6 months.\n\nExclusion Criteria:\n\nThe following exclusion criteria must NOT be present for each subject:\n\n1. Subjects with medical history that might affect oral feeding (e.g. intestinal obstruction, gastrointestinal bleeding, acute pancreatitis and accidental inhalation) within the last 1 month prior to screening.\n2. Subjects with medical history that might affect gastrointestinal functions (e.g. inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), short bowel syndrome (SBS), et al.).\n3. Subjects who cannot communicate and collaborate normally.","ALL","65 Years",{"count":70,"type":71},60,"ESTIMATED","INTERVENTIONAL",[74],"NA","The purpose of the trial is to explore the effect of exogenous postbiotics supply on the quality of life and nutritional status of elderly hemodialysis patients.\n\nParticipants will be devided into intervention group and placebo group in an 1:1 ratio.They will:\n\n1. In the treatment period for 12 weeks, intervention group receives postbiotics product while the other group receives placebo.\n2. In the subsequent 12 weeks, intervention group ends the trial and placebo group enters into remedial treatment period. Placebo group will receive postbiotics product for 12 weeks.\n\nResearchers will analyze the change of indicators such as quality of life and nutrition state of participants from the baseline to end of treatment, and compare the difference between the two group.",[77],"Hemodialysis Complication","2025-05-08",{"date":80,"type":81},"2025-05-16","ACTUAL",{"date":83,"type":81},"2024-08-01",{"date":85,"type":71},"2026-12",{"name":5,"class":6},1]