[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100401206":3},{"organization":4,"armGroups":7,"interventions":30,"overallOfficials":44,"centralContacts":59,"locations":64,"responsibleParty":81,"collaborators":84,"id":88,"slug":89,"hasResults":90,"nctId":91,"briefTitle":92,"officialTitle":92,"acronym":34,"eligibilityCriteria":93,"healthyVolunteers":90,"sex":94,"minAge":34,"maxAge":95,"enrollmentInfo":96,"targetDuration":34,"studyType":99,"phases":100,"briefSummary":102,"conditions":103,"keywords":34,"overallStatus":66,"whyStopped":34,"lastUpdateSubmitDate":108,"lastUpdatePostDateStruct":109,"startDateStruct":112,"completionDateStruct":114,"leadSponsor":116,"locationsCount":117},{"fullName":5,"class":6},"Boston Children's Hospital","OTHER",[8,14,20,25],{"label":9,"type":10,"description":11,"interventionNames":12},"Thin liquid swallows","PLACEBO_COMPARATOR","Thin liquid swallows of formula or breastmilk or other liquid",[13],"Dietary Supplement: Thin liquid swallows",{"label":15,"type":16,"description":17,"interventionNames":18},"Slightly thick liquid swallows","EXPERIMENTAL","Slightly thick liquid swallows of formula thickened with rice cereal or breastmilk or other liquid thickened with Gelmix",[19],"Dietary Supplement: Slightly thickened liquid swallows",{"label":21,"type":16,"description":22,"interventionNames":23},"Mildly thick liquid swallows","Mildly thick liquid swallows of formula thickened with rice cereal or breastmilk or other liquid thickened with Gelmix",[24],"Dietary Supplement: Mildly thickened liquid swallows",{"label":26,"type":16,"description":27,"interventionNames":28},"Moderately thick liquid swallows","Moderately thick liquid swallows of formula thickened with rice cereal or breastmilk or other liquid thickened with Gelmix",[29],"Dietary Supplement: Moderately thickened liquid swallows",[31,35,38,41],{"type":32,"name":9,"description":11,"armGroupLabels":33,"otherNames":34},"DIETARY_SUPPLEMENT",[9],null,{"type":32,"name":36,"description":17,"armGroupLabels":37,"otherNames":34},"Slightly thickened liquid swallows",[15],{"type":32,"name":39,"description":22,"armGroupLabels":40,"otherNames":34},"Mildly thickened liquid swallows",[21],{"type":32,"name":42,"description":27,"armGroupLabels":43,"otherNames":34},"Moderately thickened liquid swallows",[26],[45,48,51,54,57],{"name":46,"affiliation":5,"role":47},"Daniel R Duncan, MD, MPH","PRINCIPAL_INVESTIGATOR",{"name":49,"affiliation":5,"role":50},"Rachel Rosen, MD, MPH","STUDY_DIRECTOR",{"name":52,"affiliation":53,"role":50},"Sudarshan Jadcherla, MD","Nationwide Children's Hospital",{"name":55,"affiliation":56,"role":50},"Taher Omari, PhD","Flinders University",{"name":58,"affiliation":5,"role":50},"Samuel Nurko, MD, MPH",[60],{"name":46,"role":61,"phone":62,"phoneExt":34,"email":63},"CONTACT","617-355-0897","daniel.duncan@childrens.harvard.edu",[65],{"facility":5,"status":66,"city":67,"state":68,"zip":69,"country":70,"countryCode":71,"cosmosGeoPoint":72,"geoPoint":77,"contacts":78},"RECRUITING","Boston","Massachusetts","02115","United States","US",{"type":73,"coordinates":74},"Point",[75,76],-71.05977,42.35843,{"lat":76,"lon":75},[79],{"name":46,"role":61,"phone":80,"phoneExt":34,"email":63},"6173550897",{"type":47,"investigatorFullName":82,"investigatorTitle":83,"investigatorAffiliation":5,"oldNameTitle":34,"oldOrganization":34},"Daniel Duncan","Assistant Professor of Pediatrics",[85],{"name":86,"class":87},"National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)","NIH","100401206","effect-of-thickened-feeds-on-swallow-physiology-in-children-with-dysphagia-100401206",false,"NCT04504227","Effect of Thickened Feeds on Swallow Physiology in Children With Dysphagia","Inclusion Criteria:\n\n* Age 0 to 21 years\n* Admitted to Boston Children's Hospital after experiencing first lifetime BRUE, or with dysphagia symptoms such that they would be at risk for BRUE or other symptoms of swallowing difficulty\n* Have had videofluoroscopic swallow study performed or might have future videofluoroscopic swallow study performed.\n\nExclusion Criteria:\n\n* Any pre-existing medical diagnoses that exclude brief resolved unexplained event diagnosis including seizure disorders and cyanotic congenital heart disease\n* Any nasal\u002Fpharyngeal\u002Fesophageal anomalies that might affect safe placement of the pharyngeal motility catheter\n* Children fed exclusively by enteral tube\n* Allergy to rice cereal or Gelmix thickener, which will be used to adjust liquid viscosity","ALL","21 Years",{"count":97,"type":98},200,"ESTIMATED","INTERVENTIONAL",[101],"NA","This study will examine the effects of varying liquid viscosity on swallow physiology in infants with oropharyngeal dysphagia and brief resolved unexplained event (BRUE) and other children with dysphagia that would be at risk for symptoms of swallow dysfunction.",[104,105,106,107],"Dysphagia","Aspiration","Brief Resolved Unexplained Event (BRUE)","Apparent Life Threatening Event (ALTE)","2026-03-16",{"date":110,"type":111},"2026-03-18","ACTUAL",{"date":113,"type":111},"2021-04-01",{"date":115,"type":98},"2026-08-31",{"name":5,"class":6},1]