[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100616562":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":41,"locations":48,"responsibleParty":62,"collaborators":24,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":70,"acronym":24,"eligibilityCriteria":71,"healthyVolunteers":68,"sex":72,"minAge":73,"maxAge":74,"enrollmentInfo":75,"targetDuration":24,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":24,"overallStatus":84,"whyStopped":24,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Standard physical therapy program","ACTIVE_COMPARATOR","It will include 18 females with primary dysmenorrhea who will receive standard physical therapy program for 3 months. Hot pack or heating pad will be applied to the lower abdomen or lower back area for 15-20 minutes per session, with 3 sessions per week over a period of 12 weeks. Six stretching exercises will be applied.The females will be instructed to perform the exercise 3 days\u002Fweek.",[13],"Other: Standard physical therapy program",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard physical therapy program + Transcutaneous Tibial Nerve Stimulation (TTNS)","EXPERIMENTAL","It will include 18 females with primary dysmenorrhea who will receive TTNS 30 minutes once a week for 12 weeks, in addition to the same physical therapy program.",[13,19],"Other: Transcutaneous Tibial Nerve Stimulation (TTNS)",[21,25],{"type":6,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"The standard physical therapy program will include the application of a hot pack or heating pad to the lower abdomen or lower back for 15-20 minutes per session, three times per week for a duration of 12 weeks. The temperature of the hot pack will be maintained between 40°C and 45°C (104°F-113°F). In addition, participants will perform six stretching exercises for 30-45 minutes per session, also three times per week for 12 weeks.",[9,15],null,{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":24},"Transcutaneous Tibial Nerve Stimulation (TTNS)","The TTNS intervention will be applied once a week for 30-minute sessions over 12 weeks. The EV-906 electrostimulation device will be used for the treatment. A symmetrical biphasic current will be applied in continuous mode at 20 Hz and 200 μs. The patient will be in a supine position with knees flexed and abducted at a 90-degree angle. Stimulation will be applied to both legs using two adhesive electrodes placed cranially to the internal malleolus of each leg, with additional electrodes placed at the ipsilateral calcaneus. The stimulation intensity will be regulated between 1 and 30 mA.",[15],[30,34,38],{"name":31,"affiliation":32,"role":33},"Afaf Mohamed Botla, PhD","Assistant Professor, Cairo University","STUDY_CHAIR",{"name":35,"affiliation":36,"role":37},"Hossam Eldeen Hussein Kamel, PhD","Professor, Al-Azhar university","STUDY_DIRECTOR",{"name":39,"affiliation":40,"role":37},"Mahitab Mohamed Yosri Ibrahim, PhD","Lecturer, Cairo university",[42,47],{"name":43,"role":44,"phone":45,"phoneExt":24,"email":46},"Aya Atef Mahmoud Sonbol, B.Sc","CONTACT","+20 109 155 0191","aya.soonbol@gmail.com",{"name":39,"role":44,"phone":24,"phoneExt":24,"email":24},[49],{"facility":50,"status":24,"city":51,"state":24,"zip":24,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"Damas Central Hospital","Al Mansurah","Egypt","EG",{"type":55,"coordinates":56},"Point",[57,58],31.38069,31.03637,{"lat":58,"lon":57},[61],{"name":43,"role":44,"phone":45,"phoneExt":24,"email":46},{"type":63,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Aya Atef Mahmoud Sonbol","Principal Investigator","100616562","effect-of-transcutaneous-tibial-nerve-stimulation-on-primary-dysmenorrhea-100616562",false,"NCT07307222","Effect of Transcutaneous Tibial Nerve Stimulation on Primary Dysmenorrhea","Inclusion Criteria:\n\n* Females with a regular menstrual cycle, experiencing primary dysmenorrhea, confirmed by history and clinical diagnosis.\n* Females aged between 18 and 35 years.\n* Their BMI ranging from 20 to 29.9 kg\u002Fm².\n\nExclusion Criteria:\n\n* Females engaging in regular physical exercises prior to the study course.\n* A history of abdominal or pelvic surgery.\n* Pelvic pathologies or diseases (e.g., polycystic ovary syndrome, endometriosis, adenomyomas, or uterine fibroids).\n* Malignant or benign neoplasms in the uterus.\n* Chronic diseases, including diabetes and\u002For rheumatoid arthritis.\n* Presence of metal implants or pacemakers.\n* Any contraindications to the use of electrical stimulation (e.g., open wounds, some skin conditions…. etc.).","FEMALE","18 Years","35 Years",{"count":76,"type":77},36,"ESTIMATED","INTERVENTIONAL",[80],"NA","This study will be conducted to evaluate the effect of Transcutaneous Tibial Nerve Stimulation (TTNS) on primary dysmenorrhea.",[83],"Primary Dysmenorrhea","NOT_YET_RECRUITING","2025-12-14",{"date":87,"type":88},"2025-12-29","ACTUAL",{"date":90,"type":77},"2025-12-21",{"date":92,"type":77},"2026-03-31",{"name":5,"class":6},1]