[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100645034":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":28,"locations":34,"responsibleParty":53,"collaborators":18,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":63,"eligibilityCriteria":64,"healthyVolunteers":59,"sex":65,"minAge":66,"maxAge":18,"enrollmentInfo":67,"targetDuration":18,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":82,"overallStatus":84,"whyStopped":18,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"University of Baghdad","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Virtual Reality-Guided Imagery plus Routine Care","EXPERIMENTAL","Participants in this group will receive guided virtual reality mindfulness sessions, in addition to their routine chemotherapy care. This intervention is a non-pharmaceutical supportive approach designed to reduce pain, anxiety, and fatigue through immersive guided mindfulness and relaxation during chemotherapy cycles.",[13],"Device: Virtual Reality-Guided Imagery",{"label":15,"type":16,"description":17,"interventionNames":18},"Routine Care Only","NO_INTERVENTION","Participants in this arm will receive routine chemotherapy care only without virtual reality-guided imagery intervention.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","Virtual Reality-Guided Imagery","The intervention consists of immersive virtual reality-guided imagery delivered using a commercially available VR headset and pre-designed guided imagery software. Participants will wear the VR headset during chemotherapy sessions, which provides access to pre-recorded guided imagery programs.\n\nThese programs include standardized audiovisual content such as calming natural scenes, relaxation instructions, and breathing guidance designed to promote relaxation and distraction from pain, anxiety, and fatigue. The content is not developed by the researcher but is selected from existing validated or commercially available VR applications.\n\nEach session will be administered under supervision during chemotherapy and in addition to routine hospital care. The intervention aims to reduce symptom burden by shifting the patient's attention away from treatment-related discomfort through immersive guided imagery experiences.",[9],[26,27],"Immersive Virtual Reality","Guided imagery therapy",[29],{"name":30,"role":31,"phone":32,"phoneExt":18,"email":33},"thulfiqar mohammed abdalhussien, PhD candidate","CONTACT","07831476489","thulfiqar.abd2402p@conursing.uobaghdad.edu.iq",[35],{"facility":36,"status":18,"city":37,"state":38,"zip":18,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"National Hospital for Oncology and Hematology in Najaf Governorate","Najaf","Najaf Governorate","Iraq","IQ",{"type":42,"coordinates":43},"Point",[44,45],44.34625,32.02594,{"lat":45,"lon":44},[48,50],{"name":49,"role":31,"phone":32,"phoneExt":18,"email":33},"thoalfokar mohammed abdalhussien, PhD candidate",{"name":51,"role":52,"phone":18,"phoneExt":18,"email":18},"Thoalfokar Mohammed Al-Obaidi, PhD candidate","PRINCIPAL_INVESTIGATOR",{"type":54,"investigatorFullName":55,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"SPONSOR_INVESTIGATOR","Thoalfokar Mohammed Al-Obaidi","PhD Candidate","100645034","effect-of-virtual-reality-guided-imagery-on-pain-anxiety-and-fatigue-in-cancer-patients-undergoing-chemotherapy-100645034",false,"NCT07677436","Effect of Virtual Reality-Guided Imagery on Pain, Anxiety, and Fatigue in Cancer Patients Undergoing Chemotherapy","Effect of Virtual Reality Guided Imagery on Pain, Anxiety, and Fatigue in Cancer Patients Undergoing Chemotherapy: A Randomized Controlled Trial","VRGI-Chemo Tri","Inclusion Criteria:\n\n* Female patients aged 18 years or older.\n* Histologically confirmed breast cancer.\n* Stage I, II, or III breast cancer.\n* Underwent surgery as the initial treatment and are scheduled to receive the first cycle of adjuvant chemotherapy, with or without biologic therapy (e.g., AC or TC regimens).\n* Able to read, write, and communicate.\n* Able and willing to use a virtual reality headset.\n* Able to provide written informed consent.\n\nExclusion Criteria:\n\n* Visual or hearing impairment that prevents the use of virtual reality.\n* Serious neurological or psychiatric disorders.\n* Current participation in other non-pharmacological interventions (e.g., meditation or relaxation therapy) that could influence the study outcomes.\n* Previous experience with virtual reality-guided imagery.\n* Use of analgesics, anxiolytics, or other medications during the intervention that may affect the study outcomes.","FEMALE","18 Years",{"count":68,"type":69},108,"ESTIMATED","INTERVENTIONAL",[72],"NA","This randomized controlled trial aims to evaluate the effectiveness of virtual reality-guided imagery in reducing pain, anxiety, and fatigue among female breast cancer patients undergoing adjuvant chemotherapy. Participants will be randomly assigned to either an intervention group receiving virtual reality-guided imagery in addition to routine care, or a control group receiving routine care",[75,76,77,78,79,80,81],"Virtual Reality","Guided Imagery","Breast Cancer","Chemotherapy","Pain","Anxiety","Fatigue",[83],"Virtual Reality, Guided Imagery , Breast Cancer, Chemotherapy , Pain, Anxiety , Fatigue","NOT_YET_RECRUITING","2026-06-27",{"date":87,"type":88},"2026-06-30","ACTUAL",{"date":90,"type":69},"2026-07-01",{"date":92,"type":69},"2027-03",{"name":55,"class":6},1]