[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100483689":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":25,"centralContacts":29,"locations":37,"responsibleParty":79,"collaborators":82,"id":84,"slug":85,"hasResults":86,"nctId":87,"briefTitle":88,"officialTitle":89,"acronym":10,"eligibilityCriteria":90,"healthyVolunteers":86,"sex":91,"minAge":92,"maxAge":10,"enrollmentInfo":93,"targetDuration":10,"studyType":96,"phases":10,"briefSummary":97,"conditions":98,"keywords":10,"overallStatus":40,"whyStopped":10,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":113,"locationsCount":114},{"fullName":5,"class":6},"Chinese University of Hong Kong","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patient with ischemic stroke with suspected large vessel occlusion",null,"The investigators shall recruit patients that meet the following inclusion criteria:\n\n1. Patient who are over 18 years of age.\n2. Patient with ischemic stroke with suspected large vessel occlusion (LVO), defined as occlusion of the internal carotid artery (ICA), M1 or M2 segment of the middle cerebral artery (MCA), or basilar artery (BA).",[13,14],"Diagnostic Test: Thrombus analyses","Diagnostic Test: Imaging assessment",[16,21],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":10},"DIAGNOSTIC_TEST","Thrombus analyses","Physical, histology, biochemical or protein expressions of the thrombi obtained from thrombectomy procedures may contain information regarding the etiology of stroke and relevant disease pathology. The investigators shall store the thrombus, if any, yielded from thrombectomy procedures for future analyses.",[9],{"type":17,"name":22,"description":23,"armGroupLabels":24,"otherNames":10},"Imaging assessment","All imaging data will be deidentified before assessment. Plain computer tomography of the brain (CT brain), CT angiography (CTA), CT perfusion (CTP), magnetic resonance imaging of the brain (MRI), digital subtraction imaging (DSA) will be analysed. The investigators shall blind the assessors from treatment choice and outcome in all analyses that require human assessment.",[9],[26],{"name":27,"affiliation":5,"role":28},"Bonaventure Yiu Ming IP, MB ChB","PRINCIPAL_INVESTIGATOR",[30,34],{"name":27,"role":31,"phone":32,"phoneExt":10,"email":33},"CONTACT","852-28902002","bonaventureip@cuhk.edu.hk",{"name":35,"role":31,"phone":32,"phoneExt":10,"email":36},"Thomas Wai Hong LEUNG, MB ChB","drtleung@cuhk.edu.hk",[38,56,69],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Linyi People's Hospital","RECRUITING","Linyi","Shandong","276000","China","CN",{"type":47,"coordinates":48},"Point",[49,50],118.34278,35.06306,{"lat":50,"lon":49},[53],{"name":54,"role":31,"phone":10,"phoneExt":10,"email":55},"Fengyuan Che, MD,PhD","fyche1971@163.com",{"facility":57,"status":40,"city":58,"state":42,"zip":59,"country":44,"countryCode":45,"cosmosGeoPoint":60,"geoPoint":64,"contacts":65},"The Affiliated Hospital of Medical College of Qingdao University","Qingdao","266000",{"type":47,"coordinates":61},[62,63],120.38042,36.06488,{"lat":63,"lon":62},[66],{"name":67,"role":31,"phone":10,"phoneExt":10,"email":68},"Hao Wang, MD","neurology_hao@163.com",{"facility":5,"status":40,"city":70,"state":10,"zip":10,"country":70,"countryCode":71,"cosmosGeoPoint":72,"geoPoint":76,"contacts":77},"Hong Kong","HK",{"type":47,"coordinates":73},[74,75],114.17469,22.27832,{"lat":75,"lon":74},[78],{"name":27,"role":31,"phone":32,"phoneExt":10,"email":33},{"type":28,"investigatorFullName":80,"investigatorTitle":81,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Dr. IP Yiu Ming Bonaventure","Assistant Professor",[83],{"name":39,"class":6},"100483689","effective-translation-of-endovascular-thrombectomy-trials-into-real-world-practice-in-the-asia-pacific-100483689",false,"NCT05578300","Effective Translation of Endovascular Thrombectomy Trials Into Real-world Practice in the Asia-Pacific","Effective Translation of Endovascular Thrombectomy Trials Into Real-world Practice in the Asia-Pacific: a Multicenter, Prospective Registry (ENDURE-APAC)","Inclusion Criteria:\n\n* Patient who are over 18 years of age.\n* Patient with ischemic stroke with suspected large vessel occlusion (LVO), defined as occlusion of the internal carotid artery (ICA), M1 or M2 segment of the middle cerebral artery (MCA), or basilar artery (BA).\n\nExclusion Criteria:\n\n* Patient with isolated vertebral artery occlusion not involving the BA.","ALL","18 Years",{"count":94,"type":95},350,"ESTIMATED","OBSERVATIONAL","As a major breakthrough of acute stroke treatment over the past decade, endovascular thrombectomy (EVT) drastically improved neurological recovery and survival in patients with large vessel occlusion (LVO) ischemic strokes in major clinical trials. Nevertheless, much remained uncertain about the implementation of scientific evidence of EVT into real-world benefits. For instance, healthcare policies that influence critical time-matrices, endovascular thrombectomy techniques that may enhance success rate or prevent complications, or advanced imaging techniques that allow precise prognosis or expansion of treatment populations, should be evaluated. On the other hand, capturing LVO patients who were not able to undergo EVT may reveal the gap between clinical trials and real-world practice in the Asia-Pacific.\n\nIn this multicenter prospective collaboration across the Asian-Pacific, the investigators aim to evaluate the determinants of effective EVT in the real-world setting.",[99,100,101,102,103,104],"Ischemic Stroke","Stroke","Stroke, Acute","Stroke, Ischemic","Brain Diseases","Major Adverse Cardiovascular Event","2026-03-16",{"date":107,"type":108},"2026-03-18","ACTUAL",{"date":110,"type":108},"2022-10-21",{"date":112,"type":95},"2032-12-31",{"name":5,"class":6},3]