[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100514489":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":27,"centralContacts":32,"locations":41,"responsibleParty":74,"collaborators":77,"id":83,"slug":84,"hasResults":85,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":26,"eligibilityCriteria":89,"healthyVolunteers":90,"sex":91,"minAge":92,"maxAge":93,"enrollmentInfo":94,"targetDuration":18,"studyType":97,"phases":98,"briefSummary":100,"conditions":101,"keywords":106,"overallStatus":44,"whyStopped":18,"lastUpdateSubmitDate":110,"lastUpdatePostDateStruct":111,"startDateStruct":114,"completionDateStruct":116,"leadSponsor":118,"locationsCount":119},{"fullName":5,"class":6},"Central Department of Public Health","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention arm","EXPERIMENTAL","Hypertensive patients with uncontrolled BP in the intervention group will receive mobile phone text messages in the Nepali language and accept the phone call from the trained research nurse on their given mobile. They will also get the opportunity to ask questions and clarification during the phone call. However, text messaging would be only one way.",[13],"Behavioral: Phone call and text Messages",{"label":15,"type":16,"description":17,"interventionNames":18},"Control arm","NO_INTERVENTION","The control arm will receive the usual routine maintenance. In Nepal, hypertensive patients usually receive a prescription of antihypertensive medicine and advise for follow-up as the standard care. In addition, a pamphlet containing information about hypertension and required behavior modifications will be provided to all study participants, including the control arm.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","Phone call and text Messages","The intervention consists of recommended lifestyle counselling (on a healthy diet, physical activity, smoking, alcohol intake, medication adherence and continuity of care). This counselling will be provided through the research nurse at baseline and for six months (tentative plan phone call once a month; frequency and duration will be finalized based on formative study) by calling on participants' given mobile numbers. In addition, text message reminders on the same topics will be delivered regularly (2-3 times a week) for six months. The counselling and message will focus on three domains of COM-B; capabilities needed, opportunities and practical tools, and motivation strategies informed by behaviour change techniques.",[9],[26],"TelTex4BP",[28],{"name":29,"affiliation":30,"role":31},"Buna Bhandari Bhattarai, PhD","Florida State University","PRINCIPAL_INVESTIGATOR",[33,38],{"name":34,"role":35,"phone":36,"phoneExt":18,"email":37},"Buna Bhandari","CONTACT","9851320990","buna.bhandari@gmail.com",{"name":39,"role":35,"phone":18,"phoneExt":18,"email":40},"Rabina Dhakal, MPH","dhakalrabina@gmail.com",[42,58],{"facility":43,"status":44,"city":45,"state":46,"zip":18,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"Sahid Gangalal National Heart Center","RECRUITING","Kathmandu","Bagmati","Nepal","NP",{"type":50,"coordinates":51},"Point",[52,53],85.3206,27.70169,{"lat":53,"lon":52},[56],{"name":57,"role":35,"phone":18,"phoneExt":18,"email":18},"Rikesh Tamrakar, DM",{"facility":59,"status":44,"city":45,"state":60,"zip":61,"country":47,"countryCode":48,"cosmosGeoPoint":62,"geoPoint":64,"contacts":65},"Apara Innovations Pvt Ltd","Pradesh 3 (Bagmati)","40660",{"type":50,"coordinates":63},[52,53],{"lat":53,"lon":52},[66,68,69,71],{"name":67,"role":35,"phone":18,"phoneExt":18,"email":37},"Dr Buna Bhandari, PhD",{"name":39,"role":35,"phone":18,"phoneExt":18,"email":40},{"name":70,"role":31,"phone":18,"phoneExt":18,"email":18},"Buna Bhandari Bhattarai",{"name":72,"role":73,"phone":18,"phoneExt":18,"email":18},"Rikesh Tamrakar","SUB_INVESTIGATOR",{"type":31,"investigatorFullName":34,"investigatorTitle":75,"investigatorAffiliation":76,"oldNameTitle":18,"oldOrganization":18},"Assistant Professor","Indiana University",[78,80],{"name":79,"class":6},"Harvard School of Public Health (HSPH)",{"name":81,"class":82},"Apara Innovations Pvt. Ltd","UNKNOWN","100514489","effectiveness-and-adoption-of-the-teltex4bp-intervention-among-adults-with-hypertension-in-nepal-100514489",false,"NCT05979168","Effectiveness and Adoption of the TelTex4BP Intervention Among Adults With Hypertension in Nepal","Effectiveness and Adoption of the Structured mHealth Intervention for Improving Blood Pressure Control (TelTex4BP) Among Adults With Hypertension in Nepal: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Clinical diagnosis of hypertension\n* Currently receiving\u002Fprescribed blood pressure-lowering medication for more than three month\n* With uncontrolled blood pressure (\\>140\u002F90mm of Hg)\n* Should have access to a mobile phone\n* Able to read text messages ( by themselves\u002Fwith the help of family)\n\nExclusion Criteria:\n\n* Diagnosed with myocardial infarction, stroke, and kidney failure\n* Severe mental illness, cognitive impairment\n* Pregnant women or in the postpartum period",true,"ALL","18 Years","70 Years",{"count":95,"type":96},500,"ESTIMATED","INTERVENTIONAL",[99],"NA","Despite evidence of preventing cardiovascular disease (CVD) risk through lifestyle changes, many patients with hypertension (HTN) do not comply with this and suffer from CVD and other complications. A previous study using a structured lifestyle intervention program has reported a 14% decrease in the 10-year risk of developing CVD at one year among hypertensive and diabetes patients. Low and Middle-Income countries (LMICs) struggle with a shortage of health workers to deliver such interventions. In this context, mobile phones can contribute to bridging this gap by incorporating them into the health system for health intervention delivery. There is a need to develop contextual mHealth intervention adapted to local needs and culture and test its effectiveness in LMIC settings like Nepal. Our previous small-scale pilot mHealth (text messages) study reported promising evidence in reducing blood pressure among hypertensive patients in the intervention arm \\[adjusted reduction in systolic blood pressure (BP) -6.50 (95% CI, -12.6; -0.33) and diastolic BP -4.60 (95% CI, -8.16; -1.04)\\], with a greater proportion achieving target BP (70% vs 48% in the control arm, p = 0.006)\\] and improving treatment compliance (p \\\u003C 0.001) in Nepal. This finding supports the expansion to a large-scale trial of a structured mHealth intervention to see its long-term effectiveness and sustainability for patients with HTN to improve BP control and reduce CVD risk. Hence, this study aims to assess the effectiveness of a behavioural intervention through mHealth (telephone\u002Fmobile phone calls and text messages) informed by the RE-AIM framework for improving blood pressure control among patients with hypertension in a hospital (Manamohan Cardiothoracic Vascular and Transplant Center) of Kathmandu, Nepal.",[102,103,104,105],"Hypertension","Medication Adherence","Blood Pressure","Cardiovascular Diseases",[107,108,102,109],"Mobile Intervention","Blood Pressure Control","Randomized Controlled Trial","2026-06-09",{"date":112,"type":113},"2026-06-11","ACTUAL",{"date":115,"type":113},"2025-11-02",{"date":117,"type":96},"2027-12-31",{"name":5,"class":6},2]