[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100562776":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":35,"locations":41,"responsibleParty":59,"collaborators":26,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":26,"eligibilityCriteria":67,"healthyVolunteers":68,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":26,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":26,"overallStatus":44,"whyStopped":26,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Wecare Probiotics Co., Ltd.","INDUSTRY",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Probiotics group","EXPERIMENTAL","10B CFU\u002FSachet\u002FDay BC99 before meals; Storage: Store in cool and dry place without sun exposure.",[13],"Dietary Supplement: Probiotic group",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo","PLACEBO_COMPARATOR","Maltodextrin one Sachet\u002FDay before meals; Storage: Store in cool and dry place without sun exposure.",[19],"Dietary Supplement: Placebo group",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DIETARY_SUPPLEMENT","Probiotic group","The experimental phase of this study lasted for 56 days, during which we will measure participants' liver function, such as alanine aminotransferase (ALT) at baseline and end.",[9],null,{"type":22,"name":28,"description":24,"armGroupLabels":29,"otherNames":26},"Placebo group",[15],[31],{"name":32,"affiliation":33,"role":34},"Ying Wu, Dr.","Henan University of Science and Technology","STUDY_CHAIR",[36],{"name":37,"role":38,"phone":39,"phoneExt":26,"email":40},"Wu yin, Dr.","CONTACT","CN 18639283502","wuying2000@126.com",[42],{"facility":43,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Wu Ying","RECRUITING","Luoyang","Henan","471000","China","CN",{"type":51,"coordinates":52},"Point",[53,54],112.43684,34.67345,{"lat":54,"lon":53},[57],{"name":32,"role":38,"phone":58,"phoneExt":26,"email":40},"18639283502",{"type":60,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100562776","effectiveness-and-safety-of-probiotics-in-protecting-liver-function-100562776",false,"NCT06607562","Effectiveness and Safety of Probiotics in Protecting Liver Function","Protective Effect of Probiotics BC99 on Liver Function in Long-Term Alcohol Consumers: A Randomized, Double-Blind, Placebo-Controlled Trial","Inclusion Criteria:\n\n1. A history of long-term heavy alcohol consumption, equivalent to ethanol intake ≥40g\u002Fday for over 1 year. The conversion formula is: ethanol (g) = volume of ethanol-containing beverage (mL) × ethanol content (%) × 0.8 (specific gravity of ethanol);\n2. Body Mass Index (BMI) between 18kg\u002Fm² and 25kg\u002Fm²;\n3. Voluntarily signed a written informed consent form, agreeing to participate in this study;\n4. Agreed to comply with the study protocol and restrictions;\n5. Subjects (including male participants) have no plans for conception from 14 days prior to screening until 6 months after the end of the trial and voluntarily agree to use effective contraception.\n\nExclusion Criteria:\n\n1. Patients with various types of viral hepatitis, autoimmune liver disease, drug-induced liver damage, vascular liver disease, genetic metabolic liver disease, or primary liver cancer;\n2. Individuals who have recently consumed substances with similar functions to the tested product, potentially affecting the study results;\n3. Patients with severe allergies or immune deficiencies;\n4. Pregnant, breastfeeding, or women with plans for pregnancy;\n5. Individuals with severe diseases of vital organs such as cardiovascular, pulmonary, hepatic, renal conditions, or those with diabetes, severe thyroid disorders, metabolic diseases, malignant tumors, or severe immune system disorders;\n6. Individuals who have used antibiotics within the past two weeks;\n7. Participants who did not comply with the required consumption of the tested product or missed follow-ups, making it impossible to evaluate the effectiveness;\n8. Other participants deemed unsuitable by the researchers.",true,"ALL","19 Years","65 Years",{"count":73,"type":74},80,"ESTIMATED","INTERVENTIONAL",[77],"NA","To evaluate the effectiveness and safety of using probiotics to protect the liver function of long-term alcohol consumers",[80],"Alcohol Abuse","2024-09-18",{"date":83,"type":84},"2024-09-23","ACTUAL",{"date":86,"type":84},"2024-06-03",{"date":88,"type":74},"2025-04-15",{"name":5,"class":6},1]