[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100631613":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":30,"locations":36,"responsibleParty":70,"collaborators":74,"id":78,"slug":79,"hasResults":80,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":84,"eligibilityCriteria":85,"healthyVolunteers":80,"sex":86,"minAge":87,"maxAge":88,"enrollmentInfo":89,"targetDuration":25,"studyType":92,"phases":93,"briefSummary":95,"conditions":96,"keywords":103,"overallStatus":106,"whyStopped":25,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":116},{"fullName":5,"class":6},"University of Vic - Central University of Catalonia","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Control group","ACTIVE_COMPARATOR","An exercise program based on guidance provided during the informational session and the provided brochure is followed, without planning, adaptation, or supervision. Recommendations include aerobic and strength training exercises.",[13],"Other: Recommendation Exercise Program",{"label":15,"type":16,"description":17,"interventionNames":18},"Experimental group","EXPERIMENTAL","A supervised, planned, and adapted therapeutic physical exercise program is implemented according to fatigue levels and the phase of the neoadjuvant chemotherapy cycle. The program includes three supervised sessions per week combining aerobic and strength training exercises.",[19],"Other: PREDU Exercise Program",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PREDU Exercise Program","The intervention includes a supervised, multimodal therapeutic exercise program in two phases: 2 weeks before chemotherapy and 16 weeks during chemotherapy.\n\nPre-chemotherapy (2 weeks): 3 weekly home-based aerobic sessions and 2 supervised strength sessions (30 min each) using free weights or guided equipment.\n\nDuring chemotherapy (16 weeks): 3 supervised sessions per week combining aerobic and strength training (20-50 min each). Aerobic exercises use stationary cycling or treadmill moderate continuous (70% HRmax) and interval training (Low HIIT 85%HRmax). Strength exercises are 2 sets of 8-12 reps at 50-80% of 1RM, using guided weights and elastic bands.\n\nThe program is adapted and planned according to participants' fatigue and chemotherapy cycle.",[15],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Recommendation Exercise Program","Participants follow unsupervised exercise recommendations during the 2 weeks before and the 16 weeks of chemotherapy. Aerobic exercises are 30-45 minutes, 3-4 times per week (walking, swimming, cycling), and strength exercises are 2 sessions per week, 30 minutes each, targeting upper limbs, trunk, and lower limbs. Participants are responsible for following these recommendations on their own, without individualized adaptation or supervision, aiming to meet WHO exercise guidelines for oncology populations.",[9],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Meritxell Parareda Ventura, Physiotherapist","CONTACT","(+34) 93 881 60 25","meritxell.parareda@uvic.cat",[37,53,61],{"facility":38,"status":25,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Consorci Hospitalari de Vic","Vic","Barcelona","08500","Spain","ES",{"type":45,"coordinates":46},"Point",[47,48],2.25486,41.93012,{"lat":48,"lon":47},[51],{"name":25,"role":33,"phone":52,"phoneExt":25,"email":25},"(+34) 93 889 11 11",{"facility":54,"status":25,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":55,"geoPoint":57,"contacts":58},"Facultat de Ciències de la Salut i del Benestar de la Universitat de Vic (UVIC-UCC) Universitat de Vic- Universitat Central de Catalunya",{"type":45,"coordinates":56},[47,48],{"lat":48,"lon":47},[59],{"name":60,"role":33,"phone":34,"phoneExt":25,"email":35},"Meritxell Parareda Ventura",{"facility":62,"status":25,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":63,"geoPoint":65,"contacts":66},"Hospital Universitari de la Santa Creu",{"type":45,"coordinates":64},[47,48],{"lat":48,"lon":47},[67],{"name":68,"role":33,"phone":69,"phoneExt":25,"email":35},"Josep Ortiz","(+34) 93 883 33 00",{"type":71,"investigatorFullName":72,"investigatorTitle":73,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Meritxell Parareda","Principal Investigator Professor Meritxell Parareda Ventura",[75],{"name":76,"class":77},"Col·legi Fisioterapeutes de Catalunya","UNKNOWN","100631613","effectiveness-of-a-multimodal-outpatient-supervised-physical-activity-program-to-improve-tolerance-and-efficacy-of-chemotherapy-in-adults-with-breast-lung-and-colon-cancer-100631613",false,"NCT07502963","Effectiveness of a Multimodal Outpatient Supervised Physical Activity Program to Improve Tolerance and Efficacy of Chemotherapy in Adults With Breast, Lung and Colon Cancer","Effectiveness of a Multimodal Outpatient Supervised Physical Activity Program to Improve Tolerance and Efficacy of Chemotherapy in Adults With Breast, Lung and Colon Cancer: Randomized Clinical Trial.","PREDU","Inclusion Criteria:\n\n* Women and men aged 35 to 65 years\n* Diagnosed with stage II, III, or IV breast, lung, or colon cancer\n* Scheduled to start neoadjuvant chemotherapy\n* Able and willing to provide written informed consent\n\nExclusion Criteria:\n\n* Musculoskeletal or neurological disorders that prevent proper execution of the exercises\n* Uncontrolled infections or symptoms\n* Comorbidities such as chronic obstructive pulmonary disease (COPD), respiratory failure, or recent cardiovascular events within the past 6 months\n* Body mass index (BMI) over 35\n* Pregnant women\n* Difficulty understanding the purpose and procedures of the study","ALL","35 Years","65 Years",{"count":90,"type":91},70,"ESTIMATED","INTERVENTIONAL",[94],"NA","This clinical study evaluates whether a supervised, multimodal therapeutic exercise program started before chemotherapy and continued during treatment can improve treatment outcomes in patients aged 35 to 65 years with breast, lung, or colon cancer.\n\nThe study hypothesis is that participation in this exercise program improves tolerance to chemotherapy, allowing patients to receive more than 85% of the planned relative dose intensity. In addition, the program is expected to enhance treatment effectiveness by increasing the rate of complete radiological response.\n\nThe main objective of the study is to assess the effectiveness of a supervised, multimodal therapeutic exercise program performed before and during chemotherapy in improving both treatment tolerance and treatment efficacy in patients with breast, lung, and colon cancer.",[97,98,99,100,101,102],"Breast Cancer","Lung Cancer (Non-Small Cell)","Colorectal Cancer","Physical Activity","Neoadjuvant Chemotherapy Tolerance","Strength and Endurance",[97,98,104,100,105,101],"Colorectal cancer","Strength and endurance","NOT_YET_RECRUITING","2026-03-24",{"date":109,"type":110},"2026-03-31","ACTUAL",{"date":112,"type":91},"2026-04",{"date":114,"type":91},"2027-10",{"name":5,"class":6},3]