[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100590052":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":29,"locations":35,"responsibleParty":65,"collaborators":18,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":18,"eligibilityCriteria":73,"healthyVolunteers":69,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":18,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":90,"overallStatus":38,"whyStopped":18,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":108,"completionDateStruct":110,"leadSponsor":112,"locationsCount":113},{"fullName":5,"class":6},"Federal Center of Cerebrovascular Pathology and Stroke, Russian Federation Ministry of Health","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Active Touch Sensory Training Intervention","EXPERIMENTAL","Participants in this arm undergo a novel sensory rehabilitation protocol based on the Active Touch Paradigm. This intervention integrates real-time functional electrical stimulation with voluntary finger movement across a touch-sensitive screen to explore virtual textures of varying densities. Each time a participant's finger crosses an invisible virtual grating line, a tactile sensation is delivered via electrical stimulation to the index finger. The system records finger trajectory, response time, and decision-making accuracy, offering real-time visual and tactile feedback to enhance sensory discrimination and neuroplasticity. The training consists of 180 trials divided into six blocks with breaks in between, and assessments are conducted before and after the intervention using tools such as the Touch-Test monofilament, Fugl-Meyer Assessment, and ARAT. This arm aims to evaluate the efficacy of active engagement and sensorimotor integration in promoting sensory recovery after stroke.",[13],"Device: Active Touch-Based Sensory Training",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard Rehabilitation Without Sensory Training","NO_INTERVENTION","Participants in this arm receive standard post-stroke rehabilitation as prescribed by their physicians but do not undergo any form of targeted sensory training or participate in the Active Touch Paradigm. They complete the same pre- and post-intervention assessments as the experimental group, including tactile sensitivity testing with von Frey monofilaments, the Fugl-Meyer Assessment, the Action Research Arm Test (ARAT), and the Nine-Hole Peg Test (9HPT). This arm serves as a control condition to evaluate the specific effects of the active touch-based sensory intervention on sensory and motor recovery in stroke survivors.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"DEVICE","Active Touch-Based Sensory Training","This intervention combines functional electrical stimulation with active tactile exploration of virtual textures. Using a touch-sensitive screen and a programmable functional electrical stimulator (MotionStim 8), participants explore two invisible virtual textures by moving their index finger across the screen. Each time the finger crosses a virtual texture line, an electrical pulse is delivered to the finger, simulating tactile sensation. Participants are asked to compare the density of two virtual textures and select the denser one. The stimulation is synchronized with finger movement to ensure real-time sensory feedback. The training consists of 50 trials divided into 5 blocks, and is designed to enhance tactile discrimination and proprioception through sensorimotor integration. The paradigm is interactive, personalized based on individual sensory thresholds, and aims to promote neural plasticity in stroke survivors.",[9],[26],{"name":27,"affiliation":5,"role":28},"Galina Ivanova, Professor","STUDY_CHAIR",[30],{"name":31,"role":32,"phone":33,"phoneExt":18,"email":34},"Maria Volodina, PhD in Physiology","CONTACT","+79162528715","mariavolodina@yandex.ru",[36],{"facility":37,"status":38,"city":39,"state":18,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Federal Center of Cerebrovascular Pathology and Stroke","RECRUITING","Moscow","117997","Russia","RU",{"type":44,"coordinates":45},"Point",[46,47],37.61781,55.75204,{"lat":47,"lon":46},[50,52,54,57,58,61,63],{"name":27,"role":32,"phone":18,"phoneExt":18,"email":51},"reabilivanova@mail.ru",{"name":31,"role":32,"phone":33,"phoneExt":18,"email":53},"mvolodina@hse.ru",{"name":55,"role":56,"phone":18,"phoneExt":18,"email":18},"Timur Ivanov, MD","SUB_INVESTIGATOR",{"name":31,"role":56,"phone":18,"phoneExt":18,"email":18},{"name":59,"role":60,"phone":18,"phoneExt":18,"email":18},"Alexei Ossadtchi, Doctor of Sciences","PRINCIPAL_INVESTIGATOR",{"name":62,"role":56,"phone":18,"phoneExt":18,"email":18},"Alexey Tumialis, PhD",{"name":64,"role":56,"phone":18,"phoneExt":18,"email":18},"Ekaterina Ivanova, MD",{"type":66,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100590052","effectiveness-of-active-exploration-of-simulated-textures-for-sensorimotor-recovery-100590052",false,"NCT06962397","Effectiveness of Active Exploration of Simulated Textures for Sensorimotor Recovery","Research on the Effectiveness of the Method of Active Examination of Artificially Simulated Textures Generated by Programmable Transcutaneous Electrical Stimulation as a Method of Restoring Sensorimotor Function of the Upper Limbs","Inclusion Criteria:\n\n* Episode of stroke confirmed by neuroimaging\n* More than one month post-stroke\n* Montreal Cognitive Assessment (MoCA) score ≥ 20\n* Barthel Index score ≥ 3\n* Ability to understand and follow instructions\n* Informed consent for participation and data collection\n* Age 18-80 years\n\nExclusion Criteria:\n\n* Presence of depressive symptoms (HADS-Depression \\> 11)\n* Upper limb paresis score below 35 on the Fugl-Meyer scale\n* Sensory impairment score below 3 or above 10 on the Fugl-Meyer scale","ALL","18 Years","80 Years",{"count":78,"type":79},20,"ESTIMATED","INTERVENTIONAL",[82],"NA","Parallel-group, single-blinded controlled clinical trial. The study includes people aged 18-80 years, more than one month after stroke, with confirmed diagnosis, MoCA ≥ 20, and Barthel Index ≥ 3.\n\nThe control group receives standard rehabilitation. The experimental group also receives active sensory training with programmable electrical stimulation to simulate virtual textures.\n\nSensory function was assessed before and after the training using standard tests, including Fugl-Meyer, ARAT, 9HPT, and monofilament testing.",[85,86,87,88,89],"Stroke","Sensorimotor Impairment Affecting the Upper Limb","Sensory Deficit","Rehabilitation","Tactile Disorders",[85,91,92,93,94,95,96,97,98,99,100,101,102,103],"Sensorimotor rehabilitation","Tactile stimulation","Upper limb recovery","Electrical stimulation","Virtual textures","Sensory training","Neurorehabilitation","Post-stroke therapy","Active touch paradigm","Functional electrical stimulation","Proprioception","Touch sensitivity","Stroke rehabilitation technology","2025-05-19",{"date":106,"type":107},"2025-05-22","ACTUAL",{"date":109,"type":107},"2024-10-08",{"date":111,"type":79},"2026-01",{"name":5,"class":6},1]