[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100625265":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":25,"locations":31,"responsibleParty":48,"collaborators":18,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":18,"eligibilityCriteria":58,"healthyVolunteers":54,"sex":59,"minAge":60,"maxAge":18,"enrollmentInfo":61,"targetDuration":18,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":70,"overallStatus":74,"whyStopped":18,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Investigación en Hemofilia y Fisioterapia","NETWORK",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental group","EXPERIMENTAL","Patients with hemophilia allocated to the intervention group will receive a structured pain education program delivered through targeted educational sessions.",[13],"Other: Educational group",{"label":15,"type":16,"description":17,"interventionNames":18},"Control group","NO_INTERVENTION","Participants allocated to the control group will not receive physiotherapy sessions based on pain education and will continue with their usual routine of physical activity and exercise.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"OTHER","Educational group","Patients with hemophilia will receive a structured pain education program delivered through targeted educational sessions.",[9],[26],{"name":27,"role":28,"phone":29,"phoneExt":18,"email":30},"Rubén Cuesta-Barriuso, PhD","CONTACT","0034 985103386","cuestaruben@uniovi.es",[32],{"facility":33,"status":18,"city":34,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Universidad de Oviedo","Oviedo","Principality of Asturias","33006","Spain","ES",{"type":40,"coordinates":41},"Point",[42,43],-5.84476,43.36029,{"lat":43,"lon":42},[46],{"name":27,"role":28,"phone":47,"phoneExt":18,"email":30},"0034 985 103 386",{"type":49,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"PRINCIPAL_INVESTIGATOR","Rubén Cuesta-Barriuso","Principal Investigator","100625265","effectiveness-of-an-educational-program-for-pain-management-in-patients-with-hemophilic-arthropathy-100625265",false,"NCT07420387","Effectiveness of an Educational Program for Pain Management in Patients With Hemophilic Arthropathy","Effectiveness of an Educational Program for Pain Management in Patients With Hemophilic Arthropathy: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Adult patients with a confirmed diagnosis of hemophilia A or B.\n* Presence of hemophilic arthropathy.\n* Presence of chronic pain.\n\nExclusion Criteria:\n\n* Patients with neurological or cognitive impairments that preclude understanding of the educational sessions.\n* Patients who have undergone surgical intervention within the two months preceding the educational program","MALE","18 Years",{"count":62,"type":63},70,"ESTIMATED","INTERVENTIONAL",[66],"NA","Introduction: Hemophilic arthropathy is a common complication of hemophilia, characterized by chronic pain, functional limitation, and impaired quality of life. Cognitive-emotional factors such as catastrophizing and kinesiophobia significantly influence the pain experience, supporting the rationale for interventions grounded in the biopsychosocial model and pain neuroscience education.\n\nObjective: To evaluate the efficacy of an educational program based on pain neurobiology, emotional regulation, and cognitive-behavioral strategies on the pain experience in adult patients with hemophilic arthropathy.\n\nMethods: A randomized, controlled clinical trial with two parallel groups (intervention and control) and three assessment time points (pre-intervention, post-intervention, and 6-month follow-up) will be conducted. A total of 70 adult patients with hemophilia A or B and a diagnosis of hemophilic arthropathy with chronic pain will be enrolled and randomly assigned in a 1:1 ratio. The intervention group will receive a structured educational program consisting of three 60-minute sessions focused on pain neurobiology, emotional regulation, cognitive restructuring, coping strategies, and physiological downregulation techniques, including supervised physical activity as an analgesic strategy. The control group will continue with usual care without additional educational intervention. The primary outcome will be pain intensity and pain interference, assessed using the Brief Pain Inventory. Statistical analyses will be performed using repeated-measures ANOVA, with the Group × Time interaction considered the primary effect of interest, under the intention-to-treat principle.\n\nExpected Results: It is anticipated that the intervention group will demonstrate a statistically and clinically significant reduction in pain intensity and pain-related functional interference compared with the control group. A sustained clinical improvement at six months is also expected, supporting the utility of structured educational interventions as a safe and complementary strategy in the management of chronic pain in patients with hemophilic arthropathy.",[69],"Hemophilia",[69,71,72,73],"Hemophilic arthropathy","Chronic pain","Pain neuroscience education","NOT_YET_RECRUITING","2026-02-18",{"date":77,"type":78},"2026-02-20","ACTUAL",{"date":80,"type":63},"2026-03-27",{"date":82,"type":63},"2027-09-11",{"name":5,"class":6},1]