[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100574677":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":29,"locations":39,"responsibleParty":57,"collaborators":25,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":65,"acronym":25,"eligibilityCriteria":66,"healthyVolunteers":63,"sex":67,"minAge":68,"maxAge":25,"enrollmentInfo":69,"targetDuration":25,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":78,"overallStatus":42,"whyStopped":25,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"University of Valencia","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Standard Rehabilitation","ACTIVE_COMPARATOR","Participants in this group will receive a standardized post-operative rehabilitation protocol specifically designed for ACL reconstruction recovery. The protocol includes progressive exercises tailored to the recovery phases: early recovery (Phase 1), strength and neuromuscular control (Phase 2), agility and landing mechanics (Phase 3), and return to sport (Phase 4). Sessions will be supervised weekly by trained Physical Therapists, with additional unsupervised exercises to be performed at home or in the gym. This protocol follows current evidence-based guidelines without the incorporation of blood flow restriction therapy",[13],"Other: Standard Rehabilitation",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard Rehabilitation + Blood Flow Restriction","EXPERIMENTAL","Participants in this group will follow the same standardized post-operative rehabilitation protocol as the Active Comparator group, tailored to the recovery phases for ACL reconstruction (Phases 1-4). In addition, during Phase 2 (weeks 2-12), participants will undergo blood flow restriction (BFR) therapy during specific strengthening exercises. The BFR intervention involves applying a pneumatic cuff to the proximal thigh to achieve 70-80% arterial occlusion, combined with low-intensity resistance exercises (15-20% of 1RM). This approach aims to enhance muscle strength and recovery while minimizing joint stress. Sessions will be supervised weekly by trained Phyisical Therapists.",[19],"Other: Blood Flow Restriction",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Blood Flow Restriction","Blood Flow Restriction (BFR) therapy in this study involves the application of a pneumatic cuff around the proximal thigh to restrict arterial blood flow during specific rehabilitation exercises. The cuff will be inflated to achieve 70-80% of arterial occlusion, while participants perform low-intensity resistance exercises at 15-20% of their one-repetition maximum (1RM). BFR therapy will be used during Phase 2 of rehabilitation (weeks 2-12) alongside a standardized rehabilitation protocol. The intervention will be closely monitored by trained Physical Therapists to ensure safety and efficacy, with pressure adjustments made in real-time based on the participant's exercise performance. This intervention distinguishes itself by its use of BFR, a technique that is not part of conventional ACL rehabilitation",[15],null,{"type":6,"name":9,"description":27,"armGroupLabels":28,"otherNames":25},"The Standard Rehabilitation (RHB) intervention in this study consists of a structured, evidence-based protocol designed to optimize recovery after anterior cruciate ligament (ACL) reconstruction. This rehabilitation protocol is implemented across four phases. The rehabilitation will be supervised by experienced Physical Therapists, and participants will be given a tailored home exercise program to complement the supervised sessions. The intervention aims to optimize recovery, restore function, and reduce the risk of re-injury.",[9],[30,35],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},"Borja Perez-Dominguez, Ph.D.","CONTACT","+34 697 46 46 80","f.borja.perez@uv.es",{"name":36,"role":32,"phone":37,"phoneExt":25,"email":38},"Enrique Falco-Crespo, PT","+34 669 72 38 19","enrique.falco@uv.es",[40],{"facility":41,"status":42,"city":43,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Faculty of Physiotherapy","RECRUITING","Valencia","46010","Spain","ES",{"type":48,"coordinates":49},"Point",[50,51],-0.37966,39.47391,{"lat":51,"lon":50},[54],{"name":55,"role":32,"phone":56,"phoneExt":25,"email":34},"Borja Perez-Dominguez, PhD","+34 697464680",{"type":58,"investigatorFullName":59,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Borja Pérez-Domínguez","Assistant Professor","100574677","effectiveness-of-blood-flow-restriction-in-postoperative-rehabilitation-for-anterior-cruciate-ligament-injuries-a-pilot-study-100574677",false,"NCT06762392","Effectiveness of Blood Flow Restriction in Postoperative Rehabilitation for Anterior Cruciate Ligament Injuries. A Pilot Study.","Inclusion Criteria:\n\n* Patients aged between 18 and 45 years.\n* Patients who have undergone anterior cruciate ligament (ACL) reconstruction surgery\n\nExclusion Criteria:\n\n* Cardiovascular comorbidities\n* Severe metabolic disorders or postoperative complications\n* Previous joint disorders requiring surgery on the affected leg\n* Pregnancy\n* Coagulation disorders","ALL","18 Years",{"count":70,"type":71},40,"ESTIMATED","INTERVENTIONAL",[74],"NA","The goal of this clinical trial is to evaluate the effectiveness of adding Blood Flow Restriction (BFR) therapy to a standardized rehabilitation protocol in patients undergoing postoperative rehabilitation following anterior cruciate ligament (ACL) repair surgery.\n\nThe main questions it aims to answer are:\n\nDoes combining BFR therapy with a standardized rehabilitation protocol improve functional recovery compared to rehabilitation alone?\n\nDoes the addition of BFR therapy enhance muscle strength and reduce recovery time in patients after ACL repair surgery?\n\nParticipants will undergo their assigned rehabilitation protocol and will be assessed prior to and after the intervention to determine if the addition of BFR therapy to the standard rehabilitation programme significantly improves functional recovery, muscle strength, and overall rehabilitation outcomes following ACL repair surgery.",[77],"Anterior Cruciate Ligament Reconstruction Rehabilitation",[79,80,81,22,82],"Physical Therapy","Rehabilitation","Anterior Cruciate Ligament","Randomized Clinical Trial","2026-03-04",{"date":85,"type":86},"2026-03-05","ACTUAL",{"date":88,"type":86},"2025-01-01",{"date":90,"type":71},"2027-01-01",{"name":5,"class":6},1]