[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100635275":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":35,"centralContacts":40,"locations":50,"responsibleParty":95,"collaborators":24,"id":97,"slug":98,"hasResults":99,"nctId":100,"briefTitle":101,"officialTitle":101,"acronym":24,"eligibilityCriteria":102,"healthyVolunteers":99,"sex":103,"minAge":104,"maxAge":105,"enrollmentInfo":106,"targetDuration":24,"studyType":109,"phases":110,"briefSummary":112,"conditions":113,"keywords":115,"overallStatus":119,"whyStopped":24,"lastUpdateSubmitDate":120,"lastUpdatePostDateStruct":121,"startDateStruct":124,"completionDateStruct":126,"leadSponsor":128,"locationsCount":129},{"fullName":5,"class":6},"Baskent University","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"hiltherapy","EXPERIMENTAL","In this group Nd:YAG laser (1064 nm) will be applied to participants with high-peak power (3 kW), pulse duration 120-150 μs, frequency 10-30 Hz, energy density 360-1780 mJ\u002Fcm². Protective eyewear will be used. Protocol: scanning phase (rapid paravertebral scan), initial phase (trigger point scan), and final phase (slow scan of initial area). Total energy: 2,500 J\u002Fcm² (1,000 + 500 + 1,000). 15 sessions will be applied for 3 weeks, 15 min\u002Fsession. Participants will also receive 15 sessions (5 sessions\u002Fweek for 3 weeks).",[13],"Device: Hiltherapy",{"label":15,"type":16,"description":17,"interventionNames":18},"Physiotherapy","ACTIVE_COMPARATOR","US + Hot pack + TENS will be applied to the participants. Hot pack (15 × 50 cm, 15 min), ultrasound (1 MHz, 1.5 W\u002Fcm², 4+4 min bilateral), and TENS (20 min, 80 Hz, 180 μs, 4 electrodes 5 × 5 cm) will be applied for 15 sessions for 3 weeks. Participants will also receive 15 sessions (5 sessions\u002Fweek for 3 weeks).",[19],"Device: physiotherapy",{"label":21,"type":22,"description":23,"interventionNames":24},"control group","NO_INTERVENTION","Participants will receive 15 sessions (5 sessions\u002Fweek for 3 weeks). Each session will last 15 minutes under physiotherapist supervision and include lumbar extension, pelvic tilt, and core stabilization exercises as tolerated.",null,[26,31],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":24},"DEVICE","Hiltherapy","Nd:YAG laser (1064 nm) will be applied to the participants with high-peak power (3 kW), pulse duration 120-150 μs, frequency 10-30 Hz, energy density 360-1780 mJ\u002Fcm². Protective eyewear will be used. Protocol: scanning phase (rapid paravertebral scan), initial phase (trigger point scan), and final phase (slow scan of initial area). Total energy: 2,500 J\u002Fcm² (1,000 + 500 + 1,000). 15 sessions for 3 weeks, 15 min\u002Fsession.",[9],{"type":27,"name":32,"description":33,"armGroupLabels":34,"otherNames":24},"physiotherapy","Combination of US + Hot pack + TENS will be applied to the participants Hot pack (15 × 50 cm, 15 min), ultrasound (1 MHz, 1.5 W\u002Fcm², 4+4 min bilateral), and TENS (20 min, 80 Hz, 180 μs, 4 electrodes 5 × 5 cm) for 15 sessions for 3 weeks.",[15],[36],{"name":37,"affiliation":38,"role":39},"Sevgi İkbali Afşar, Prof. Dr.","BASKENT UNİVERSİTY","STUDY_DIRECTOR",[41,46],{"name":42,"role":43,"phone":44,"phoneExt":24,"email":45},"Ozlem Kuculmez, assist prof dr","CONTACT","+905556205210","ahmedzmm@outlook.com",{"name":47,"role":43,"phone":48,"phoneExt":24,"email":49},"Derya aydil","+903122129065\u002F2234","etikkurul@baskent.edu.tr",[51,70,87],{"facility":5,"status":24,"city":52,"state":53,"zip":54,"country":55,"countryCode":24,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"Ankara","Bahcelievler","06490","Turkey (Türkiye)",{"type":57,"coordinates":58},"Point",[59,60],32.85427,39.91987,{"lat":60,"lon":59},[63,67],{"name":64,"role":43,"phone":65,"phoneExt":24,"email":66},"Seyhan Sözay, Prof. dr.","+903122237333","hastahaklari@baskent.edu.tr",{"name":68,"role":43,"phone":69,"phoneExt":24,"email":66},"Sevgi Ikbali Afşaar, Prof Dr.","+905388868596",{"facility":5,"status":24,"city":52,"state":24,"zip":54,"country":55,"countryCode":24,"cosmosGeoPoint":71,"geoPoint":73,"contacts":74},{"type":57,"coordinates":72},[59,60],{"lat":60,"lon":59},[75,78,82,85],{"name":76,"role":43,"phone":24,"phoneExt":24,"email":77},"Sevgi İkbali Afşar, prof dr.","ikbaliafsar@hotmail.com",{"name":79,"role":43,"phone":80,"phoneExt":24,"email":81},"Ozlem Kuculmez, Asist Prof Dr.","+905555620521","akanozlem07@gmail.com",{"name":83,"role":84,"phone":24,"phoneExt":24,"email":24},"Ahmed Zaki Mohammed Mohammed, asistant dr","PRINCIPAL_INVESTIGATOR",{"name":37,"role":86,"phone":24,"phoneExt":24,"email":24},"SUB_INVESTIGATOR",{"facility":88,"status":24,"city":52,"state":24,"zip":54,"country":55,"countryCode":24,"cosmosGeoPoint":89,"geoPoint":91,"contacts":92},"Başkent University Ankara Hospital",{"type":57,"coordinates":90},[59,60],{"lat":60,"lon":59},[93],{"name":94,"role":43,"phone":69,"phoneExt":24,"email":77},"Sevgi Ikbali Afsar",{"type":96,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR","100635275","effectiveness-of-high-intensity-laser-therapy-in-management-of-lumbar-disc-herniation-100635275",false,"NCT07550569","Effectiveness of High Intensity Laser Therapy in Management of Lumbar Disc Herniation","Inclusion Criteria:\n\n* Males and females aged 18-65 years\n* Diagnosed with lumbar disc herniation via MRI and presenting with low back pain\n* No History of lumbar physical therapy in the last 3 months\n* No History of analgesic or muscle relaxant use since initial presentation\n* Willingness to participate and signed informed consent\n\nExclusion Criteria:\n\n* History of Fibromyalgia diagnosis\n* History of acute trauma\n* History of Lumbar instability\n* History of Rheumatologic disease\n* Motor deficits or myelopathy\n* History of Lumbar injections in the last 3 months\n* History of Previous lumbar surgery\n* Pregnancy\n* Pacemaker\n* Cognitive impairment or unwillingness to comply with treatment","ALL","18 Years","65 Years",{"count":107,"type":108},150,"ESTIMATED","INTERVENTIONAL",[111],"NA","Chronic lumbar radiculopathy is a multifactorial condition typically caused by lumbar disc herniation, where degenerative changes lead to nerve root compression, resulting in radiating pain, sensory disturbances, and motor deficits. Management requires a multidisciplinary, primarily conservative approach centered on physical therapy, including exercise, electrotherapy, and other non-invasive modalities. Exercise plays a key role in improving spinal stability, mobility, posture, and neuromuscular coordination, while treatments like transcutaneous electrical nerve stimulation (TENS) and high-intensity laser therapy (HILT) provide pain relief through neuromodulation and tissue regeneration mechanisms. Recent evidence suggests that combining HILT with exercise may enhance functional outcomes more effectively than exercise alone. Accordingly, this study aims to compare the effectiveness of exercise alone, exercise combined with HILT, and exercise combined with conventional therapies (ultrasound, hot pack, and TENS) in patients with lumbar disc herniation. Patients aged 18-65 will be randomly assigned to three groups and undergo a 3-week treatment program, with outcomes assessed through measures of pain, disability, range of motion, and quality of life.",[114],"Lomber Disc Herniation",[116,117,118],"Intervertebral Disc Displacement","Back Pain","Laser Therapy","NOT_YET_RECRUITING","2026-04-20",{"date":122,"type":123},"2026-04-24","ACTUAL",{"date":125,"type":108},"2026-05-01",{"date":127,"type":108},"2027-02-28",{"name":5,"class":6},3]