[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100600435":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":34,"centralContacts":39,"locations":50,"responsibleParty":67,"collaborators":44,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":44,"eligibilityCriteria":76,"healthyVolunteers":72,"sex":77,"minAge":78,"maxAge":44,"enrollmentInfo":79,"targetDuration":44,"studyType":82,"phases":83,"briefSummary":85,"conditions":86,"keywords":89,"overallStatus":53,"whyStopped":44,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"Wonkwang University Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"HPI-guided Monitoring","EXPERIMENTAL","Participants in this group will receive continuous Hypotension Prediction Index (HPI) monitoring using the Edwards Lifesciences HemoSphere platform. Interventions such as fluid boluses or vasopressors will be administered when HPI ≥ 85, following institutional protocols.",[13],"Device: Hypotension Prediction Index Monitoring",{"label":15,"type":16,"description":17,"interventionNames":18},"Control Group","ACTIVE_COMPARATOR","Participants in this group will receive standard post-anesthesia care unit (PACU) monitoring, including non-invasive blood pressure, heart rate, and oxygen saturation. Interventions will follow usual care without guidance from HPI.",[19],"Other: Standard PACU Monitoring",[21,28],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Hypotension Prediction Index Monitoring","HPI monitoring is performed using the Edwards Lifesciences HemoSphere platform to provide real-time hypotension prediction based on arterial pressure waveform analysis. Interventions such as fluid bolus or vasopressor are administered per protocol when HPI ≥ 85.",[9],[27],"HPI Monitoring",{"type":6,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"Standard PACU Monitoring","Standard monitoring in the post-anesthesia care unit (PACU), including non-invasive blood pressure, heart rate, and oxygen saturation measurements. No Hypotension Prediction Index (HPI) monitoring is used. Interventions are performed according to routine institutional practices.",[15],[33],"Usual Care",[35],{"name":36,"affiliation":37,"role":38},"Cheol Lee, M.D.,Ph.D","Department of anesthesiology and pain medicine, Wonkwang University Hospital","PRINCIPAL_INVESTIGATOR",[40,46],{"name":41,"role":42,"phone":43,"phoneExt":44,"email":45},"Cheol Lee, M.D.,Ph.D.","CONTACT","+82-1066131252",null,"ironyii@wku.ac.kr",{"name":47,"role":42,"phone":48,"phoneExt":44,"email":49},"Cheolhyeong Lee, M.D.","+82-10-7736-9397","Leecheolhyeong@gmail.com",[51],{"facility":52,"status":53,"city":54,"state":55,"zip":56,"country":57,"countryCode":44,"cosmosGeoPoint":58,"geoPoint":63,"contacts":64},"Wonkwag UH","RECRUITING","Iksan","Jeollabukdo","54538","South Korea",{"type":59,"coordinates":60},"Point",[61,62],126.95444,35.94389,{"lat":62,"lon":61},[65],{"name":66,"role":42,"phone":48,"phoneExt":44,"email":49},"Cheolhyeong Lee, M.D",{"type":38,"investigatorFullName":68,"investigatorTitle":69,"investigatorAffiliation":5,"oldNameTitle":44,"oldOrganization":44},"Cheol Lee,MD,PhD,","Professor","100600435","effectiveness-of-hypotension-prediction-index-hpi-in-preventing-hypotension-in-the-post-anesthesia-care-unit-pacu-100600435",false,"NCT07097454","Effectiveness of Hypotension Prediction Index (HPI) in Preventing Hypotension in the Post-Anesthesia Care Unit (PACU)","Effectiveness of Hypotension Prediction Index (HPI) in Preventing Hypotension in the Post-Anesthesia Care Unit (PACU): A Prospective, Randomized, Controlled Trial","Inclusion Criteria:\n\n* Age ≥ 19 years\n* Undergoing elective surgery under general anesthesia\n* Presence of intra-arterial catheter at the end of surgery\n* Expected PACU stay of ≥ 30 minutes\n* Provided written informed consent\n\nExclusion Criteria:\n\n* Immediate postoperative ICU admission\n* Use of vasopressors during emergence from anesthesia\n* ASA physical status classification of V\n* Known contraindications to arterial line placement\n* Participation in another interventional study within 30 days","ALL","19 Years",{"count":80,"type":81},210,"ESTIMATED","INTERVENTIONAL",[84],"NA","Postoperative hypotension in the post-anesthesia care unit (PACU) is common and linked to adverse outcomes. The Hypotension Prediction Index (HPI) predicts hypotensive events intraoperatively, but its PACU application is unexplored. This study aims to investigate the effectiveness of HPI-guided monitoring in preventing PACU hypotension.",[87,88],"Hypotension","Postoperative Complications",[90,91,92,93,94],"Hypotension Prediction Index (HPI)","PACU","Hemodynamic Monitoring","Arterial Pressure Waveform","HemoSphere","2026-06-24",{"date":97,"type":98},"2026-06-26","ACTUAL",{"date":100,"type":81},"2026-07-15",{"date":102,"type":81},"2026-09-11",{"name":5,"class":6},1]