[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100623222":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":28,"centralContacts":28,"locations":28,"responsibleParty":29,"collaborators":28,"id":31,"slug":32,"hasResults":33,"nctId":34,"briefTitle":35,"officialTitle":36,"acronym":28,"eligibilityCriteria":37,"healthyVolunteers":33,"sex":38,"minAge":28,"maxAge":28,"enrollmentInfo":39,"targetDuration":28,"studyType":42,"phases":43,"briefSummary":45,"conditions":46,"keywords":28,"overallStatus":48,"whyStopped":28,"lastUpdateSubmitDate":49,"lastUpdatePostDateStruct":50,"startDateStruct":53,"completionDateStruct":55,"leadSponsor":57,"locationsCount":28},{"fullName":5,"class":6},"Universitat Internacional de Catalunya","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Interdental Brush Group","EXPERIMENTAL","Participants use interdental brushes for interproximal plaque control around posterior implants.",[13],"Device: Participants assigned to this intervention group are instructed to perform daily interproximal plaque control around implant-supported crowns using the allocated interdental oral hygiene device (inter",{"label":15,"type":10,"description":16,"interventionNames":17},"Oral Irrigator Group","Participants use an oral irrigator for interproximal plaque control around posterior implants.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Superfloss Group","Participants use Superfloss for interproximal plaque control around posterior implants.",[13],[23],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":28},"DEVICE","Participants assigned to this intervention group are instructed to perform daily interproximal plaque control around implant-supported crowns using the allocated interdental oral hygiene device (inter","Participants will receive a structured oral hygiene intervention using interproximal oral hygiene devices specifically designed for use around posterior single implants diagnosed with peri-implant mucositis. The intervention consists of standardized instruction and supervised use of the assigned interproximal device according to manufacturer recommendations and a predefined clinical protocol. The device will be used by participants for daily interproximal plaque control around the implant site throughout the study period. Clinical and microbiological outcomes related to biofilm accumulation and peri-implant soft tissue inflammation will be assessed at predefined follow-up visits. No pharmacological agents are administered as part of the intervention.",[9,15,19],null,{"type":30,"investigatorFullName":28,"investigatorTitle":28,"investigatorAffiliation":28,"oldNameTitle":28,"oldOrganization":28},"SPONSOR","100623222","effectiveness-of-interproximal-cleaning-devices-for-biofilm-removal-around-posterior-single-implants-with-peri-implant-mucositis-100623222",false,"NCT07393828","Effectiveness of Interproximal Cleaning Devices for Biofilm Removal Around Posterior Single Implants With Peri-Implant Mucositis","Efficacy of Biofilm Removal of Different Interproximal Oral Hygiene Devices Around Posterior Single Implants in Peri-Implant Mucositis: A Randomized Clinical Trial","Inclusion Criteria:\n\nAdults aged ≥18 years. Presence of at least one posterior single dental implant in function for ≥12 months.\n\nDiagnosis of peri-implant mucositis, defined as bleeding on probing with probing depths ≤5 mm and no radiographic bone loss beyond initial remodeling.\n\nGood general health (ASA I-II). Ability and willingness to comply with study procedures and follow-up visits. Provision of written informed consent.\n\nExclusion Criteria:\n\nDiagnosis of peri-implantitis (radiographic bone loss beyond initial remodeling).\n\nUncontrolled systemic diseases affecting periodontal or peri-implant health (e.g., uncontrolled diabetes mellitus).\n\nUse of systemic antibiotics or anti-inflammatory drugs within the previous 3 months.\n\nCurrent pregnancy or lactation. Current smoker of \\>10 cigarettes\u002Fday. History of periodontal therapy or professional implant maintenance within the previous 3 months.\n\nUse of medications known to affect bone metabolism (e.g., bisphosphonates). Inability to perform adequate oral hygiene or to attend scheduled study visits.","ALL",{"count":40,"type":41},75,"ESTIMATED","INTERVENTIONAL",[44],"NA","This randomized clinical trial aims to evaluate and compare the efficacy of different interproximal oral hygiene devices for biofilm removal around posterior single dental implants in patients diagnosed with peri-implant mucositis.\n\nPeri-implant mucositis is a reversible inflammatory condition of the peri-implant soft tissues caused primarily by bacterial biofilm accumulation. Effective plaque control is essential for the prevention of disease progression to peri-implantitis. However, there is limited clinical evidence regarding the comparative effectiveness of different interproximal oral hygiene devices in implant-supported sites.\n\nA total of approximately 75 patients with posterior single implants and peri-implant mucositis will be recruited. Participants will be randomly allocated to one of the study groups, each using a specific interproximal oral hygiene device as part of their daily oral hygiene regimen. All participants will receive standardized oral hygiene instructions at baseline.\n\nClinical parameters related to peri-implant inflammation and plaque accumulation will be assessed at baseline and at follow-up visits at 1, 3, and 6 months. The primary outcome is the reduction of peri-implant biofilm accumulation. Secondary outcomes include changes in clinical inflammatory parameters around the implants.\n\nThe results of this study are expected to provide clinically relevant evidence to support evidence-based recommendations for interproximal oral hygiene in patients with dental implants affected by peri-implant mucositis.",[47],"Peri-implant Mucositis","NOT_YET_RECRUITING","2026-02-02",{"date":51,"type":52},"2026-02-06","ACTUAL",{"date":54,"type":41},"2026-02",{"date":56,"type":41},"2027-06",{"name":5,"class":6}]