[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100462379":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":22,"centralContacts":26,"locations":36,"responsibleParty":83,"collaborators":11,"id":85,"slug":86,"hasResults":87,"nctId":88,"briefTitle":89,"officialTitle":90,"acronym":11,"eligibilityCriteria":91,"healthyVolunteers":92,"sex":93,"minAge":94,"maxAge":11,"enrollmentInfo":95,"targetDuration":11,"studyType":98,"phases":99,"briefSummary":101,"conditions":102,"keywords":105,"overallStatus":39,"whyStopped":11,"lastUpdateSubmitDate":108,"lastUpdatePostDateStruct":109,"startDateStruct":112,"completionDateStruct":114,"leadSponsor":116,"locationsCount":117},{"fullName":5,"class":6},"Uppsala University","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":11},"Treatment with night splint after percutaneous needle fasciotomy","NO_INTERVENTION",null,{"label":13,"type":14,"description":11,"interventionNames":15},"No treatment with night splint after percutaneous needle fasciotomy","EXPERIMENTAL",[16],"Other: No night splint",[18],{"type":6,"name":19,"description":20,"armGroupLabels":21,"otherNames":11},"No night splint","Instead of the usual treatment with a night splint for three months after percutaneous needle fasciotomy patients do not receive treatment with a night splint.",[13],[23],{"name":24,"affiliation":5,"role":25},"Stephan Wilbrand, MD, PhD","PRINCIPAL_INVESTIGATOR",[27,32],{"name":28,"role":29,"phone":30,"phoneExt":11,"email":31},"Daniel Muder, MD","CONTACT","0046-23-490000","daniel.muder@surgsci.uu.se",{"name":33,"role":29,"phone":34,"phoneExt":11,"email":35},"Antje Straatmann, MD","0046-18-6110000","antje.straatmann@akademiska.se",[37,56,68],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Falu Lasarett","RECRUITING","Falun","Dalarna County","79182","Sweden","SE",{"type":46,"coordinates":47},"Point",[48,49],15.62597,60.60357,{"lat":49,"lon":48},[52,53],{"name":28,"role":29,"phone":30,"phoneExt":11,"email":31},{"name":54,"role":29,"phone":30,"phoneExt":11,"email":55},"Anna-Karin Tibell, MD","anna-karin.tibell@regiondalarna.se",{"facility":57,"status":39,"city":58,"state":59,"zip":60,"country":43,"countryCode":44,"cosmosGeoPoint":61,"geoPoint":65,"contacts":66},"Akademiska Sjukhuset","Uppsala","Uppsala County","75185",{"type":46,"coordinates":62},[63,64],17.63889,59.85882,{"lat":64,"lon":63},[67],{"name":33,"role":29,"phone":34,"phoneExt":11,"email":35},{"facility":69,"status":39,"city":70,"state":71,"zip":72,"country":43,"countryCode":44,"cosmosGeoPoint":73,"geoPoint":77,"contacts":78},"Universitetssjukhuset Örebro","Örebro","Örebro County","70185",{"type":46,"coordinates":74},[75,76],15.2066,59.27412,{"lat":76,"lon":75},[79],{"name":80,"role":29,"phone":81,"phoneExt":11,"email":82},"Madeleine Harryson, MD","0046-19-6023656","madeleine.harryson@regionorebrolan.se",{"type":84,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100462379","effectiveness-of-night-splinting-after-percutaneous-needle-fasciotomy-in-dupuytrens-contracture-100462379",false,"NCT05300893","Effectiveness of Night Splinting After Percutaneous Needle Fasciotomy in Dupuytren's Contracture","Effectiveness of Night Splinting After Percutaneous Needle Fasciotomy in Dupuytren's Contracture - a Randomised Controlled Multicenter Trial","Inclusion Criteria:\n\n* 18 years of age and older,\n* Palpable Dupuytren strand with passive extension deficit according to stadium 1 and 2 of the classification of Tubiana in one or two fingers excluding the thumb, defined as at least 30 degrees in the MCP joint and\u002For at least 20 degrees in the PIP joint and a maximum of 75 degrees in the MCP or PIP joint\n\nExclusion Criteria:\n\n* Multiple, invasive or wide strands in the palm,\n* Skin irritation,\n* Strand localization in the digit only,\n* Digital nerve injury,\n* Any former treatment for Dupuytren's contracture in the same digit,\n* Thumb contracture,\n* Stadium 3 and 4 according to the classification of Tubiana",true,"ALL","18 Years",{"count":96,"type":97},154,"ESTIMATED","INTERVENTIONAL",[100],"NA","Dupuytren's contracture (DC) is associated with progressive finger flexion and extension deficit caused by fibrosis in the palm and digits. Treatment options include minimally invasive procedures such as percutaneous needle fasciotomy (PNF) and collagenase clostridium histolyticum injections as well as open fasciectomy. PNF has recently become more popular in Sweden because it is an office-based procedure which is relatively easy to perform without the usual risks and costs of open surgery.\n\nAfter treatment with PNF patients usually continue with supervised rehabilitation, which includes physical therapy and night splinting. Whether night splinting is beneficial in terms of reducing recurrence of DC is currently debated.\n\nThis study aims to investigate whether night splinting after performed PNF helps to reduce recurrence rate or not. Patients who meet the inclusion criteria will be randomized into two groups: The first group will be treated as usual with physical therapy and night splinting after PNF. The second group will be treated with physical therapy without night splinting after PNF. Follow up includes physical examination regarding active range of motion, sensation and grip strength at procedure day and 2 weeks, 3, 12 and 36 months later as well as questionnaires regarding hand function, pain and quality of life at procedure day and 3, 12 and 36 months later. Patients who are randomized into the second group (no night splinting) will also be examined 3 weeks after PNF for observation in case of an early impairment regarding extension deficit.",[103,104],"Dupuytren Contracture","Dupuytren's Disease",[106,107],"Percutaneous needle fasciotomy","Splint","2024-05-30",{"date":110,"type":111},"2024-05-31","ACTUAL",{"date":113,"type":111},"2022-09-14",{"date":115,"type":97},"2027-01",{"name":5,"class":6},3]