[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100624856":3},{"organization":4,"armGroups":7,"interventions":21,"overallOfficials":26,"centralContacts":26,"locations":45,"responsibleParty":58,"collaborators":62,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":26,"eligibilityCriteria":74,"healthyVolunteers":75,"sex":76,"minAge":77,"maxAge":26,"enrollmentInfo":78,"targetDuration":26,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":87,"overallStatus":91,"whyStopped":26,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Ningbo University","OTHER",[8,17],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention Group","EXPERIMENTAL","Pregnant women receiving antenatal care at all community health service centers in Yinzhou District, Ningbo, allocated to the intervention group.",[13,14,15,16],"Other: Preterm birth risk scoring system","Device: Transvaginal ultrasound cervical length measurement","Drug: Vaginal Progesterone","Procedure: Cervical cerclage",{"label":18,"type":6,"description":19,"interventionNames":20},"Usual antenatal care","Pregnant women receiving antenatal care at all community health service centers in Beilun District, Ningbo, allocated to the control group.",[14,15,16],[22,27,32,35,40],{"type":6,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"Preterm birth risk scoring system","Assessment using the validated preterm birth risk scoring system in early pregnancy to stratify women into risk categories.",[9],null,{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":26},"DEVICE","Transvaginal ultrasound cervical length measurement","Women identified as high risk by the preterm birth risk scoring system will undergo transvaginal ultrasound measurement of cervical length during the mid-trimester (16-24 weeks of gestation).",[9],{"type":28,"name":29,"description":33,"armGroupLabels":34,"otherNames":26},"Transvaginal ultrasound measurement of cervical length performed at 16-24 weeks of gestation for women considered at increased risk according to clinician judgment and standard clinical practice, without application of the preterm birth risk scoring system.",[18],{"type":36,"name":37,"description":38,"armGroupLabels":39,"otherNames":26},"DRUG","Vaginal Progesterone","Administration of vaginal progesterone for women with cervical length ≤25 mm, according to guideline-based management.",[9,18],{"type":41,"name":42,"description":43,"armGroupLabels":44,"otherNames":26},"PROCEDURE","Cervical cerclage","Placement of cervical cerclage for women meeting established clinical guideline criteria.",[9,18],[46],{"facility":5,"status":26,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":26},"Ningbo","Zhejiang","315000","China","CN",{"type":53,"coordinates":54},"Point",[55,56],121.54945,29.87819,{"lat":56,"lon":55},{"type":59,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Liya Liu","Associate Professor",[63,66],{"name":64,"class":65},"The Affiliated Ningbo Women and Children's Hospital of Ningbo University","UNKNOWN",{"name":67,"class":65},"Yinzhou District Maternal and Child Health Care Hospital, Ningbo","100624856","effectiveness-of-targeted-cervical-length-screening-guided-by-a-preterm-birth-risk-scoring-system-in-reducing-the-rate-of-preterm-birth-100624856",false,"NCT07415070","Effectiveness of Targeted Cervical Length Screening Guided by a Preterm Birth Risk Scoring System in Reducing the Rate of Preterm Birth","Effectiveness of Targeted Cervical Length Screening Guided by a Preterm Birth Risk Scoring System in Reducing the Rate of Preterm Birth: a Cluster Non-randomized Controlled Trial","Inclusion Criteria:\n\n* ·For community health service centers:\n\n  1. Be located in the selected districts\n  2. Provide prenatal care and be responsible for the registration and follow-up management of pregnant women\n  3. Have the chief physician (or equivalent) agree to participate and to implement study-related risk assessment, referral, follow-up, and data collection procedures, and to receive standardized training\n\n     * For pregnant women:\n\n  \u003C!-- -->\n\n  1. Registered at participating community health service centers.\n  2. Singleton pregnancy.\n  3. No history of previous cervical cerclage.\n  4. Able and willing to provide written informed consent and participate in the study.\n\nExclusion Criteria:\n\n* for pregnant women:\n\n  1. Multiple pregnancies.\n  2. History of cervical cerclage.\n  3. Medical indications requiring pregnancy termination.\n  4. Any other condition that, in the opinion of the investigator, would make the participant unsuitable for the study.",true,"FEMALE","18 Years",{"count":79,"type":80},1000,"ESTIMATED","INTERVENTIONAL",[83],"NA","This cluster non-randomized controlled trial aims to evaluate the effectiveness and feasibility of a risk score-guided targeted cervical length screening strategy for the prevention of spontaneous preterm birth in routine community-based prenatal care. Pregnant women are first assessed using a simple preterm birth risk scoring system, and those identified as high risk undergo transvaginal cervical length screening followed by guideline-based preventive interventions when clinically indicated.\n\nThe primary objective of the study is to compare this targeted screening strategy with usual prenatal care in reducing the incidence of spontaneous preterm birth occurring between 28 and 36 completed weeks of gestation. Secondary objectives include evaluating the cervical length screening rate, adherence to cervical length screening recommendations, and selected maternal and neonatal outcomes.\n\nResearchers will compare outcomes between women receiving risk score-guided targeted screening and those receiving routine prenatal care without use of the risk scoring system. All participants will be followed until delivery.",[86],"Preterm Birth",[88,89,90],"Cervical length screening","Preterm birth risk score","Maternal and neonatal outcomes","NOT_YET_RECRUITING","2026-02-14",{"date":94,"type":95},"2026-02-17","ACTUAL",{"date":97,"type":80},"2026-03",{"date":99,"type":80},"2027-12",{"name":5,"class":6},1]