[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100559119":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":17,"centralContacts":28,"locations":34,"responsibleParty":50,"collaborators":17,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":17,"eligibilityCriteria":60,"healthyVolunteers":56,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":17,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":17,"overallStatus":73,"whyStopped":17,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"University of Central Lancashire","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Placebo","PLACEBO_COMPARATOR","Identical in taste and colour to the supplement juice, but with no peppermint content.",[13],"Other: Placebo",{"label":15,"type":16,"description":17,"interventionNames":18},"Brown seaweed and tart cherry blend","EXPERIMENTAL",null,[19],"Dietary Supplement: Brown seaweed and tart cherry blend",[21,25],{"type":22,"name":15,"description":23,"armGroupLabels":24,"otherNames":17},"DIETARY_SUPPLEMENT","Blend of brown seaweed and tart cherry blend taken twice daily",[15],{"type":6,"name":9,"description":26,"armGroupLabels":27,"otherNames":17},"Identical in taste and colour to the supplement, but with no brown seaweed or tart cherry.",[9],[29],{"name":30,"role":31,"phone":32,"phoneExt":17,"email":33},"Jonathan Sinclair, PhD, DSc","CONTACT","07875651533","jksinclair@uclan.ac.uk",[35],{"facility":5,"status":17,"city":36,"state":37,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"Preston","Lancashire","PR4 0PE","United Kingdom","UK",{"type":42,"coordinates":43},"Point",[44,45],-2.70452,53.76282,{"lat":45,"lon":44},[48],{"name":49,"role":31,"phone":32,"phoneExt":17,"email":33},"Jonathan Sinclair, DSc, PhD",{"type":51,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":17,"oldOrganization":17},"PRINCIPAL_INVESTIGATOR","Jonathan Sinclair","Professor","100559119","effects-of-a-brown-seaweed-tart-cherry-blend-in-mild-moderate-hypertension-100559119",false,"NCT06559982","Effects of a Brown Seaweed Tart Cherry Blend in Mild-moderate Hypertension","Effects of a Brown Seaweed Extract and Tart Cherry Blend Cardiometabolic Outcomes in Participants With Mild-moderate Hypertension an Ex-vivo Optimized Pilot Feasibility Trial","Inclusion Criteria:\n\n* Aged from 18-65 years\n* Systolic blood pressure 120 to 139 mmHg\n* Not taking prescribed medicine for blood pressure management\n* Ability to complete written questionnaires independently\n* Able to provide informed consent\n\nExclusion Criteria:\n\n* Diagnosed with diabetes mellitus and\u002F or coronary heart disease\n* Pregnant and lactating women\n* Allergy to peppermint\n* Habitual consumption of peppermint products\n* Regular consumption of antioxidant supplements\n* Body mass index larger than 40.0 kg\u002Fm2\n* Current enrolment in other clinical trials of other external therapies","ALL","18 Years","65 Years",{"count":65,"type":66},30,"ESTIMATED","INTERVENTIONAL",[69],"NA","The brown seaweed species Ascophyllum nodosum is rich in bioactive polysaccharides, proteins, peptides, lipids, pigments, and polyphenols. Similarly, Montmorency tart cherry (Prunus cerasus L.) is high in anthocyanins and polyphenols. Both substances have antioxidant, anti-inflammatory, and vasodilatory properties that target mechanisms central to hypertension and cardiometabolic diseases.\n\nDietary interventions to improve cardiovascular health are highly sought after as they possess less risk and financial burden than pharmacological drugs. Previous randomized trial has shown that both brown seaweed and tart cherry supplementation can improving systolic blood pressure and other cardiovascular\u002F blood lipids. However, to date, no research has explored a seaweed - tart cherry blend using a placebo randomized intervention in patients with hypertension.\n\nThe primary purpose of the proposed investigation is to test the ability of a seaweed - tart cherry supplementation blend to improve cardiometabolic parameters in participants with mild-moderate hypertension using a pilot\u002F feasibility study.",[72],"Hypertension","NOT_YET_RECRUITING","2024-08-18",{"date":76,"type":77},"2024-08-20","ACTUAL",{"date":79,"type":66},"2025-05-01",{"date":81,"type":66},"2026-07-01",{"name":5,"class":6},1]