[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100605325":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":37,"centralContacts":42,"locations":52,"responsibleParty":69,"collaborators":72,"id":78,"slug":79,"hasResults":80,"nctId":81,"briefTitle":82,"officialTitle":82,"acronym":32,"eligibilityCriteria":83,"healthyVolunteers":80,"sex":84,"minAge":85,"maxAge":32,"enrollmentInfo":86,"targetDuration":32,"studyType":89,"phases":90,"briefSummary":92,"conditions":93,"keywords":96,"overallStatus":54,"whyStopped":32,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":108},{"fullName":5,"class":6},"Virginia Polytechnic Institute and State University","OTHER",[8,16],{"label":9,"type":10,"description":11,"interventionNames":12},"Exclusive cigarette smokers","EXPERIMENTAL","Exclusive cigarette smokers will be recruited and will be exposed to all of the conditions described in the intervention section.",[13,14,15],"Behavioral: Nicotine Content","Behavioral: Illegal cigarette price","Behavioral: E-cigarette price",{"label":17,"type":10,"description":18,"interventionNames":19},"Dual cigarette\u002F nicotine vaping product users","Dual cigarette and nicotine vaping product users will be recruited and will be exposed to all of the conditions described in the intervention section",[13,14,15],[21,28,33],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Nicotine Content","In the full nicotine conditions, participants' preferred cigarettes and NVP products will be available in the LETM and preferred cigarettes will be available in the iETM. In the low nicotine conditions, a ban will permit only VLNCs in the LETM and preferred cigarettes will be available in the iETM.",[17,9],[27],"very-low nicotine standard",{"type":22,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"Illegal cigarette price","At each level of nicotine content, we will manipulate the price of illegal cigarettes (1xMP, 1.5x MP, 2x MP). MP is market price.",[17,9],null,{"type":22,"name":34,"description":35,"armGroupLabels":36,"otherNames":32},"E-cigarette price","At each level of nicotine content and illegal cigarette price, we will manipulate the price of e-cigarettes (1xMP, 1.5x MP, 2x MP). MP is the market price.",[17,9],[38],{"name":39,"affiliation":40,"role":41},"Roberta Freitas-Lemos, PhD","Fralin Biomedical Research Institute at Virginia Tech Carilion","PRINCIPAL_INVESTIGATOR",[43,48],{"name":44,"role":45,"phone":46,"phoneExt":32,"email":47},"Kirstin Gatchalian","CONTACT","540-526-2071","kmgatch@vtc.vt.edu",{"name":49,"role":45,"phone":50,"phoneExt":32,"email":51},"Madeleine Mason, PhD","540-526-2114","mgmason@vtc.vt.edu",[53],{"facility":40,"status":54,"city":55,"state":56,"zip":57,"country":58,"countryCode":59,"cosmosGeoPoint":60,"geoPoint":65,"contacts":66},"RECRUITING","Roanoke","Virginia","24016","United States","US",{"type":61,"coordinates":62},"Point",[63,64],-79.94143,37.27097,{"lat":64,"lon":63},[67,68],{"name":44,"role":45,"phone":46,"phoneExt":32,"email":47},{"name":39,"role":41,"phone":32,"phoneExt":32,"email":32},{"type":41,"investigatorFullName":70,"investigatorTitle":71,"investigatorAffiliation":5,"oldNameTitle":32,"oldOrganization":32},"Roberta Freitas-Lemos","Assistant Professor",[73,76],{"name":74,"class":75},"National Cancer Institute (NCI)","NIH",{"name":77,"class":6},"Medical University of South Carolina","100605325","effects-of-a-low-nicotine-standard-and-tobacco-prices-on-illegal-cigarette-purchasing-100605325",false,"NCT07161050","Effects of a Low Nicotine Standard and Tobacco Prices on Illegal Cigarette Purchasing","Inclusion Criteria:\n\n* Provide informed consent Be at least 21 years of age or older Provide a breath sample for measuring carbon monoxide (CO ≥ 8 ppm) Stable tobacco use patterns for at least two months\n\nExclusion Criteria:\n\nFor exclusive cigarette smokers:\n\nSmoke at least 10 cigarettes daily and do not use NVPs regularly (no more than 9 times in the last month).\n\nFor dual cigarette\u002FNVP users:\n\nSmoke at least 10 cigarettes daily and use NVPs at least 3 times in a week (report use of closed nicotine salt system)\n\nFor both groups:\n\nHave plans to move out of the area Have a serious or unstable physical or mental health condition Taking a tobacco cessation medication or medication that interferes with nicotine metabolism, motivation or reinforcement Report concrete, immediate plans to alter\u002Fquit using their usual nicotine products at the beginning of the study Being pregnant or lactating","ALL","21 Years",{"count":87,"type":88},70,"ESTIMATED","INTERVENTIONAL",[91],"NA","This study will investigate the effects of a very-low-nicotine cigarette (VLNC) standard, e-cigarette price, and illegal cigarette price on illegal product purchasing and alternative product use in a virtual marketplace.",[94,95],"Cigarette Smoking","E-cigarette Use",[97,98],"Experimental Tobacco Marketplace","Illegal cigarette","2026-01-14",{"date":101,"type":102},"2026-01-16","ACTUAL",{"date":104,"type":102},"2025-12-01",{"date":106,"type":88},"2026-10-07",{"name":5,"class":6},1]