[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100452558":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":30,"locations":36,"responsibleParty":54,"collaborators":25,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":25,"eligibilityCriteria":62,"healthyVolunteers":58,"sex":63,"minAge":64,"maxAge":25,"enrollmentInfo":65,"targetDuration":25,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":75,"overallStatus":77,"whyStopped":25,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"The University of Hong Kong","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"The AI-powered Technological Surrogate Physiotherapist","EXPERIMENTAL","Participants will be required to perform three 30-minute exercise sessions per week for 12 weeks, with six exercises at any one time. During the exercise sessions, participants will receiveTechnological Surrogate Physiotherapist (TSP) support which will in particular leverage AI to offer innovative features and modules dedicated to enhancing exercise monitoring and supervision, real-time performance feedback, and self-assessment.",[13],"Device: The AI-powered Technological Surrogate Physiotherapist",{"label":15,"type":16,"description":17,"interventionNames":18},"Face-to-face physiotherapist-supervised exercise program","ACTIVE_COMPARATOR","Participants will be required to visit a physiotherapist for usual face-to-face exercise therapy. Also, they will be required to perform three 30-minute home exercise sessions per week for 12 weeks. However, TSP will not be involved in this group.",[19],"Behavioral: Face-to-face physiotherapist-supervised exercise program",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","The AI-powered Technological Surrogate Physiotherapist will have three key features:\n\n1. Evidence-based exercise videos instructed by physical therapists\n2. Real-time movement feedback and performance score\n3. Exercise records.",[9],null,{"type":27,"name":15,"description":28,"armGroupLabels":29,"otherNames":25},"BEHAVIORAL","Physiotherapists will give usual face-to-face therapy. The assessment of participants' exercise movements will only be achieved in the traditional manner during face-to-face exercise sessions - by physiotherapists' visual inspection of and professional judgement on postural alignment and effectiveness, with verbal instructions for posture correction. The features of real-time movement feedback and tracking of exercise progress will not be provided.",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Calvin Kalun Or, PhD","CONTACT","(852) 3917-2587","klor@hku.hk",[37],{"facility":38,"status":25,"city":39,"state":25,"zip":40,"country":39,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"826, Haking Wong Building, Pokfulam, The University of Hong Kong, Hong Kong","Hong Kong","000","HK",{"type":43,"coordinates":44},"Point",[45,46],114.17469,22.27832,{"lat":46,"lon":45},[49,51],{"name":50,"role":33,"phone":34,"phoneExt":25,"email":35},"Kalun Or, Doctoral degree",{"name":52,"role":53,"phone":25,"phoneExt":25,"email":25},"Letong Li, Master degree","SUB_INVESTIGATOR",{"type":55,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100452558","effects-of-a-machine-learning-based-lower-limb-exercise-training-system-for-knee-pain-100452558",false,"NCT05173064","Effects of a Machine Learning-based Lower Limb Exercise Training System for Knee Pain","Development and Randomized Controlled Trial of an AI-powered Technological Surrogate Physiotherapist (TSP) Dedicated to Quality Enhancement and Cost Reduction in Knee Osteoarthritis Exercise Rehabilitation","Inclusion criteria:\n\n1. At least 50 years of age;\n2. Report having knee pain most days of the week;\n3. Has radiographic evidence of grade 2, 3, or 4 knee OA on the K-L scale in the posteroanterior and\u002For skyline view in at least 1 knee;\n4. Willing and able, both physically and cognitively, to perform the exercises required in the study protocol;\n5. Has normal or corrected-to-normal vision;\n6. Able to speak Cantonese and read Chinese, AND\n7. Able to provide written informed consent.\n\nExclusion criteria:\n\n1. Having a history of knee or hip replacement surgery;\n2. Being nonambulatory;\n3. Having systemic inflammatory arthritis (e.g., gout);\n4. Having a history of trauma (e.g., fractures around the knee, dislocation, sprains or tears of soft tissues like ligaments) or surgical arthroscopy of either knee within the past 6 months;\n5. Having intra-articular injection to the knee within the past 6 months;\n6. Having cognitive impairment;\n7. Involvement in a similar study (i.e., involving physical exercise or physical therapies for knee pain) within the past 6 months;\n8. Undergoing recent or imminent surgery (within 3 months) , OR\n9. Having medical co-morbidities that preclude participation in exercise.","ALL","50 Years",{"count":66,"type":67},176,"ESTIMATED","INTERVENTIONAL",[70],"NA","The goal of the study is to confirm the idea of AI-powered Technological Surrogate Physiotherapist (TSP), by demonstrating its effectiveness and value as a new technology-based contribution to OA healthcare. Participants will be randomized to one of two groups: (1) the conventional PT group receiving the exercise program delivered through in-person sessions; or (2) the AI-guided group following the program through the TSP after an initial PT session. All individuals will take part in the study for 12 weeks, and data will be collected at baseline and 12 weeks after randomization.",[73,74],"Pain","Knee Osteoarthritis",[76],"knee pain, physical therapy, exercise","NOT_YET_RECRUITING","2026-06-02",{"date":80,"type":81},"2026-06-04","ACTUAL",{"date":83,"type":67},"2026-05-20",{"date":85,"type":67},"2027-09-01",{"name":5,"class":6},1]