[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100536176":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":40,"responsibleParty":122,"collaborators":126,"id":148,"slug":149,"hasResults":150,"nctId":151,"briefTitle":152,"officialTitle":153,"acronym":12,"eligibilityCriteria":154,"healthyVolunteers":150,"sex":155,"minAge":156,"maxAge":12,"enrollmentInfo":157,"targetDuration":12,"studyType":160,"phases":161,"briefSummary":163,"conditions":164,"keywords":12,"overallStatus":78,"whyStopped":12,"lastUpdateSubmitDate":167,"lastUpdatePostDateStruct":168,"startDateStruct":171,"completionDateStruct":173,"leadSponsor":175,"locationsCount":176},{"fullName":5,"class":6},"Laval University","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Control group","NO_INTERVENTION","The control group will receive their usual care and will be asked to continue their usual activities and exercises for the whole project duration. Only one clinical guide exists for ataxia interventions and no specific guidelines for physiotherapy and occupational therapy interventions are specified in this guide in terms of frequency, duration and type of interventions that are effective with this population. Patients generally have an annual follow-up with a doctor or a clinical nurse at a Neuromuscular Diseases Clinic. Patients are then referred if needed for follow-up with the physiotherapist and occupational therapist. Typically, patients are referred to physiotherapy for mobility-related needs such as the introduction of a walking aid, orthotic and sometimes teaching an exercise program. In occupational therapy, patients are referred for needs such as the introduction of technical aids, home adaptation or the introduction of a wheelchair.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Intervention group","EXPERIMENTAL","The intervention group will follow a 12-week rehabilitation program, 3 times a week (two sessions in a therapy room and one session of aquatherapy).",[18],"Procedure: IMPACT - rehabIlitation prograM for sPAstiC aTaxias",[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":12},"PROCEDURE","IMPACT - rehabIlitation prograM for sPAstiC aTaxias","The rehabilitation program will last 12 weeks and consists of three training sessions of 60 minutes per week (2 sessions in a therapy room and 1 session in an adapted pool with multiple levels of water) for a total of 36 sessions. Participants will be divided into 7 subgroups of 6 participants and each sub-group will be supervised by one physiotherapist (PT) and one physiotherapy technologist for safety considerations. It will focus on these three domains: 1) postural control; balance, trunk-limbs and multi-joints control and coordination and 3) functional mobility. Each domain contains a standardized list of exercises with different difficulty levels and specific times allocation. All exercises will be executed by the participants at each session at the appropriate difficulty level. The initial level of difficulty for each exercise will be determined by the PT based on individual results of the pre-intervention assessment and on individual performance, fatigue level and safety.",[14],[26],{"name":27,"affiliation":28,"role":29},"Elise Duchesne, Ph D.","Université du Québec à Chicoutimi","STUDY_DIRECTOR",[31,35],{"name":27,"role":32,"phone":33,"phoneExt":12,"email":34},"CONTACT","418-590-3552","educhesn@uqac.ca",{"name":36,"role":32,"phone":37,"phoneExt":38,"email":39},"Andrée Hardy","418 541-1234","2369","guichetunique.slsj@ssss.gouv.qc.ca",[41,64,76,92,105],{"facility":42,"status":43,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"CIUSSS de la Capitale-Nationale, Hôpital de Baie-Saint-Paul","NOT_YET_RECRUITING","Baie-Saint-Paul","Quebec","G3Z 0K3","Canada","CA",{"type":50,"coordinates":51},"Point",[52,53],-70.49858,47.44109,{"lat":53,"lon":52},[56,58,61],{"name":57,"role":32,"phone":12,"phoneExt":12,"email":34},"Élise Duchesne, Ph. D.",{"name":59,"role":32,"phone":12,"phoneExt":12,"email":60},"Jacques Beaulieu, commissaire local aux plaintes","commissaire.plainte.ciussscn@ssss.gouv.qc.ca",{"name":62,"role":63,"phone":12,"phoneExt":12,"email":12},"Xavier Rodrigue, M.D.","SUB_INVESTIGATOR",{"facility":65,"status":43,"city":66,"state":45,"zip":67,"country":47,"countryCode":48,"cosmosGeoPoint":68,"geoPoint":72,"contacts":73},"CIUSSS de la Capitale-Nationale, Hôpital de La Malbaie","La Malbaie","G5A 1T1",{"type":50,"coordinates":69},[70,71],-70.15268,47.654,{"lat":71,"lon":70},[74,75],{"name":57,"role":32,"phone":12,"phoneExt":12,"email":34},{"name":59,"role":32,"phone":12,"phoneExt":12,"email":60},{"facility":77,"status":78,"city":79,"state":45,"zip":80,"country":47,"countryCode":48,"cosmosGeoPoint":81,"geoPoint":85,"contacts":86},"CIUSSS du Centre-Sud-de-l'Île-de-Montréal, installation Centre de réadaptation Lucie-Bruneau","RECRUITING","Montreal","H2H 2N8",{"type":50,"coordinates":82},[83,84],-73.58781,45.50884,{"lat":84,"lon":83},[87,88],{"name":57,"role":32,"phone":12,"phoneExt":12,"email":34},{"name":89,"role":32,"phone":90,"phoneExt":12,"email":91},"Céline Roy, commissaire local aux plaintes","514-593-3600","commissaireauxplaintes.ccsmtl@ssss.gouv.qc.ca",{"facility":93,"status":78,"city":94,"state":45,"zip":95,"country":47,"countryCode":48,"cosmosGeoPoint":96,"geoPoint":100,"contacts":101},"CIUSSS de la Capitale-Nationale, installation IRDPQ","Québec","G1M 2S8",{"type":50,"coordinates":97},[98,99],-71.21454,46.81228,{"lat":99,"lon":98},[102,103,104],{"name":57,"role":32,"phone":33,"phoneExt":12,"email":12},{"name":59,"role":32,"phone":12,"phoneExt":12,"email":60},{"name":62,"role":63,"phone":12,"phoneExt":12,"email":12},{"facility":106,"status":78,"city":107,"state":45,"zip":108,"country":47,"countryCode":48,"cosmosGeoPoint":109,"geoPoint":113,"contacts":114},"Clinique des maladies neuromusculaires du Centre intégré universitaire de santé et de services sociaux (CIUSSS) du Saguenay-Lac-Saint-Jean, installation Hôpital Jonquière","Saguenay","G7X 7X2",{"type":50,"coordinates":110},[111,112],-71.06573,48.41675,{"lat":112,"lon":111},[115,117,120],{"name":116,"role":32,"phone":33,"phoneExt":12,"email":34},"Élise Duchesne",{"name":118,"role":32,"phone":119,"phoneExt":12,"email":39},"Julie Bouchard, commissaire local aux plaintes","1 877 662-3963",{"name":121,"role":63,"phone":12,"phoneExt":12,"email":12},"Jean-Denis Brisson, M.D.",{"type":123,"investigatorFullName":124,"investigatorTitle":125,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"PRINCIPAL_INVESTIGATOR","Elise Duchesne","Full Professor",[127,129,131,133,135,138,140,142,144,146],{"name":128,"class":6},"McGill University",{"name":130,"class":6},"Université de Sherbrooke",{"name":132,"class":6},"Université du Québec a Montréal",{"name":134,"class":6},"University of Calgary",{"name":136,"class":137},"Corporation de recherche et d'action sur les maladies héréditaires (CORAMH)","UNKNOWN",{"name":139,"class":137},"Cégep de Jonquière",{"name":141,"class":137},"Centre intégré universitaire de santé et de services sociaux du Saguenay-Lac-St-Jean",{"name":143,"class":6},"Muscular Dystrophy Canada",{"name":145,"class":6},"University of Alberta",{"name":147,"class":6},"Integrated University Health and Social Services Center of the Capitale-Nationale","100536176","effects-of-a-supervised-rehabilitation-program-on-disease-severity-in-spastic-ataxias-100536176",false,"NCT06261424","Effects of a Supervised Rehabilitation Program on Disease Severity in Spastic Ataxias","IMPACT, a Supervised Rehabilitation Program for Spastic Ataxias: A Rater-blinded, Randomized Controlled Trial","Inclusion Criteria:\n\n* have a confirmed genetic diagnosis of ARSACS or SPG7\n* be able to maintain standing position and to transfert\n* be authorized by their treating neurologist\n* speak French or English\n* be able to give informed consent.\n\nExclusion Criteria:\n\n* have active participation in a rehabilitation program (self-reported information)\n* have another condition causing physical limitations\n* be uncomfortable in a swimming pool\n* be pregnant.","ALL","16 Years",{"count":158,"type":159},84,"ESTIMATED","INTERVENTIONAL",[162],"NA","Spastic ataxias are a group of diseases causing symptoms such as walking difficulties and balance impairments that lead to a high risk of falls. No pharmacological treatments exist to treat these diseases. Unfortunately, little effort is made to develop non-pharmacological treatments specific to spastic ataxias despite the detrimental impact of the disease on several aspects of an individual's life and the high cost of falls for society each year. The three objectives of this project are: 1) to determine the effect of a 12-week rehabilitation program on disease severity as compared with usual care for individuals with spastic ataxias; 2) to identify which factors can help (or not) the implementation of the program in the clinical settings (\"reel world\"); and 3) to explore the cost-benefits of IMPACT \\[rehabIlitation prograM for sPAstiC aTaxias\\]. The team has developed the program to specifically target symptoms present in these patients and was previously pilot-tested. Based on the results obtained in this pilot project, positive effects are expected concerning the disease severity of participants. The investigators want, with this project, provide to health care professionals an option to offer better-suited services to people living with spastic ataxia worldwide.",[165,166],"Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay","Spastic Paraplegia 7","2026-02-13",{"date":169,"type":170},"2026-02-18","ACTUAL",{"date":172,"type":170},"2024-02-01",{"date":174,"type":159},"2027-03",{"name":5,"class":6},5]