[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100499913":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":35,"locations":40,"responsibleParty":58,"collaborators":61,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":69,"acronym":70,"eligibilityCriteria":71,"healthyVolunteers":67,"sex":72,"minAge":73,"maxAge":25,"enrollmentInfo":74,"targetDuration":25,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":25,"overallStatus":42,"whyStopped":25,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"AdventHealth Translational Research Institute","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Attention control","SHAM_COMPARATOR","Static stretching",[13],"Behavioral: Progressive stretching",{"label":15,"type":16,"description":17,"interventionNames":18},"Aerobic exercise","EXPERIMENTAL","Aerobic exercise at a dose of 225 minutes per week",[19],"Behavioral: Aerobic exercise",[21,26],{"type":22,"name":15,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","Moderate- to vigorous-intensity aerobic exercise",[15],null,{"type":22,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Progressive stretching","Statistic stretching of eight major muscle groups",[9],[31],{"name":32,"affiliation":33,"role":34},"Justin C. Brown, Ph.D.","AdventHealth","PRINCIPAL_INVESTIGATOR",[36],{"name":32,"role":37,"phone":38,"phoneExt":25,"email":39},"CONTACT","407-303-5600","Justin.Brown4@AdventHealth.com",[41],{"facility":33,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"RECRUITING","Orlando","Florida","32804","United States","US",{"type":49,"coordinates":50},"Point",[51,52],-81.37924,28.53834,{"lat":52,"lon":51},[55],{"name":56,"role":37,"phone":57,"phoneExt":25,"email":39},"Justin C Brown, Ph.D.","4073035600",{"type":34,"investigatorFullName":59,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Justin Brown","Director, Exercise & Cancer Biology Research Program",[62],{"name":63,"class":64},"National Cancer Institute (NCI)","NIH","100499913","effects-of-aerobic-exercise-on-skeletal-muscle-remodeling-in-colorectal-cancer-100499913",false,"NCT05789433","Effects of Aerobic Exercise on Skeletal Muscle Remodeling in Colorectal Cancer","RESTORE","Inclusion Criteria:\n\n* Age ≥18 years\n* Histologically confirmed stage I, II, or III colon or rectal cancer\n* Completed surgical resection with curative intent\n* Completed other cancer-directed treatments\n* Engage in \\\u003C150 minutes per week of moderate- to vigorous-intensity structured endurance exercise\n* No planned major surgery during the study period\n* Readiness to exercise, as determined by a modified version of the Physical Activity Readiness Questionnaire\n* Ability to provide written informed consent\n* Provide written approval by a qualified healthcare professional\n* Willing to be randomized\n\nExclusion Criteria:\n\n* Evidence of metastatic or recurrent colorectal cancer\n* Concurrently actively treated other (non-colorectal) cancer\n* Scheduled to receive other postoperative cancer-directed treatment(s)\n* Currently pregnant, breastfeeding, or planning to become pregnant within the next 24 weeks\n* Currently participating in another study with competing outcomes\n* Contraindications to magnetic resonance imaging\n* Any dietary condition or restriction that would limit tolerance of a mixed meal challenge\n* Any other cardiovascular, pulmonary, orthopedic, neurologic, psychiatric, or other condition that, in the investigator's opinion, would preclude participation or successful compliance with the protocol\n* Any other situation that, in the opinion of the investigator, would negatively impact subject safety or successful compliance with the protocol","ALL","18 Years",{"count":75,"type":76},70,"ESTIMATED","INTERVENTIONAL",[79],"NA","The goal of this clinical trial is to quantify the effects of aerobic exercise training compared to attention control on intermuscular adipose tissue in colorectal cancer survivors.",[82,83],"Colonic Neoplasms","Rectal Neoplasms","2025-07-01",{"date":86,"type":87},"2025-07-03","ACTUAL",{"date":89,"type":87},"2023-05-01",{"date":91,"type":76},"2027-03-01",{"name":5,"class":6},1]