[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100629045":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":24,"centralContacts":35,"locations":41,"responsibleParty":57,"collaborators":61,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":71,"acronym":72,"eligibilityCriteria":73,"healthyVolunteers":69,"sex":74,"minAge":75,"maxAge":24,"enrollmentInfo":76,"targetDuration":24,"studyType":79,"phases":80,"briefSummary":82,"conditions":83,"keywords":88,"overallStatus":44,"whyStopped":24,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"University of Franche-Comté","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental group","EXPERIMENTAL","Aerobic exercise program during 6 weeks (3 session \u002F week), with 45 minutes ergocycle exercise",[13],"Behavioral: Aerobic exercise program",{"label":15,"type":16,"description":17,"interventionNames":18},"Physical activity oriented group","ACTIVE_COMPARATOR","Therapeutic education during 6 weeks (1 phone call \u002F week), with advice and exchanges to improve physical activity",[19],"Behavioral: Therapeutic education",{"label":21,"type":22,"description":23,"interventionNames":24},"Control group","NO_INTERVENTION","No intervention group during 6 weeks, participants have to maintain their lifestyle",null,[26,31],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":24},"BEHAVIORAL","Aerobic exercise program","Aerobic exercise program during 6 weeks, with 3 sessions \u002F week. Each session includes 45 minutes of ergocycle, with 9 cycles of 4 minutes at 60% of heart rate and 1 minute at 80%.",[9],{"type":27,"name":32,"description":33,"armGroupLabels":34,"otherNames":24},"Therapeutic education","Therapeutic education for 6 weeks, with one telephone call per week. Each call includes advices and exchanges to improve physical activity level.",[15],[36],{"name":37,"role":38,"phone":39,"phoneExt":24,"email":40},"Jérôme Bouchan, PhD","CONTACT","+33363082323","jerome.bouchan@umlp.fr",[42],{"facility":43,"status":44,"city":45,"state":24,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"EPHI Platform","RECRUITING","Besançon","25000","France","FR",{"type":50,"coordinates":51},"Point",[52,53],6.01815,47.24878,{"lat":53,"lon":52},[56],{"name":37,"role":38,"phone":39,"phoneExt":24,"email":40},{"type":58,"investigatorFullName":59,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"SPONSOR_INVESTIGATOR","Jérôme Bouchan","Researcher PhD",[62,65],{"name":63,"class":64},"UMR1098, EFS BFC, BESANCON","UNKNOWN",{"name":66,"class":6},"Centre Hospitalier Universitaire de Besancon","100629045","effects-of-an-aerobic-exercise-program-on-cardiovascular-risk-in-patients-with-chronic-kidney-disease-or-rheumatoid-arthritis-100629045",false,"NCT07469540","Effects of an Aerobic Exercise Program on Cardiovascular Risk in Patients With Chronic Kidney Disease or Rheumatoid Arthritis","PARCA","Inclusion Criteria:\n\n* Diagnosis of Chronic Kidney Disease (CKD) or Rheumatoid Arthritis (RA), with no other risk factors related to the disease.\n* Having a glomerular filtration rate between 45 and 20 ml\u002Fmin\u002F1.73 m², corresponding to stages III and IV not on dialysis for patients with CKD ; or have a DAS 28 score ≥ 2.6 points for patients with RA.\n* Have a medical certificate stating that there are no adverse reactions to physical activity.\n* Affiliation with a French social security scheme or beneficiary of such a scheme.\n\nExclusion Criteria:\n\n* Unstabilised corticosteroid therapy and\u002For \\>10mg prednisone\u002Fday\n* Uncontrolled high blood pressure\n* Pregnant women\n* Impaired higher functions making it impossible to understand and adhere to an aerobic exercise program\n* Inability to perform physical exercise, regardless of the cause (neurological, central or peripheral, cardiovascular or respiratory, or musculoskeletal)\n* Legal incapacity or limited legal capacity\n* Subject unlikely to cooperate with the study and\u002For low cooperation anticipated by the investigator\n* Subject without health insurance\n* Subject is in the exclusion period of another study involving human subjects that may interfere with the results of this study, particularly by affecting inflammatory status and the cardiovascular system.","ALL","50 Years",{"count":77,"type":78},90,"ESTIMATED","INTERVENTIONAL",[81],"NA","The goal of this clinical trial is to determine whether an aerobic exercise program can reduce cardiovascular risk in patients with systemic inflammation, such as those with rheumatoid arthritis and chronic kidney disease.\n\nThe main questions this study aims to address are:\n\n* Does an individualized aerobic exercise program reduce cardiovascular risk, as assessed arterial stiffness and endothelial function ?\n* What are the effects of this exercise program on inflammation and immunosenescence?\n\nResearchers will compare an individualized aerobic exercise program with a therapeutic education program (consisting of educational phone calls only) and a control group with no intervention.\n\nParticipants will:\n\n* Perform three physical activity sessions per week for six weeks (45-minute sessions at 60-80% of heart rate reserve);\n* Attend clinic visits at baseline, after the 6-week intervention, and at a 6-week follow-up after the intervention;\n* Undergo assessments including pulse wave velocity, hyperemic reactivity, and blood analyses.",[84,85,86,87],"Aerobic Exercise","Rhumatoid Arthisis","Chronic Kidney Disease","Cardiovascular (CV) Risk",[89,90,91,92],"Systemic Inflammation","Arterial Stiffness","Hyperemic reactivity","Blood analyses","2026-03-10",{"date":95,"type":96},"2026-03-13","ACTUAL",{"date":98,"type":78},"2026-03-16",{"date":100,"type":78},"2026-12-31",{"name":59,"class":6},1]