[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100558033":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":29,"centralContacts":34,"locations":39,"responsibleParty":59,"collaborators":24,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":24,"eligibilityCriteria":68,"healthyVolunteers":64,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":24,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":24,"overallStatus":42,"whyStopped":24,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Schön Klinik Berchtesgadener Land","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Excercise Training Order A and B","EXPERIMENTAL","The first series of five exercise trainings (A) involves supplemental oxygen therapy, with automatically titrated oxygen flow rates to maintain an oxygen saturation of 90-94% (A). The second series of five exercise trainings employs supplemental oxygen therapy with constant flow rates (B), as prescribed.",[13,14],"Other: Oxygen therapy - constant oxygen flow","Other: Oxygen therapy - automatic titrating oxygen flow",{"label":16,"type":10,"description":17,"interventionNames":18},"Excercise Training Order B and A","The first series of five exercise trainings employs supplemental oxygen therapy with constant flow rates (B), as prescribed.The second five series of five exercise trainings involves supplemental oxygen therapy, with automatically titrated oxygen flow rates to maintain an oxygen saturation of 90-94% (A).",[13,14],[20,25],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"Oxygen therapy - constant oxygen flow","During five exercise training sessions, oxygen therapy is delivered via prescribed constant oxygen flow",[9,16],null,{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":24},"Oxygen therapy - automatic titrating oxygen flow","During five exercise sessions, oxygen therapy is delivered via an automatically titrated oxygen flow rate to maintain an SpO2 target of 90-94%.",[9,16],[30],{"name":31,"affiliation":32,"role":33},"Andreas Rembert Koczulla, Prof. Dr.","Philipps University Marburg","PRINCIPAL_INVESTIGATOR",[35],{"name":31,"role":36,"phone":37,"phoneExt":24,"email":38},"CONTACT","0049-8652-932730","rkoczulla@schoen-klinik.de",[40],{"facility":41,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Klinikum Berchtesgadener Land, Schön Kliniken","RECRUITING","Schönau am Königssee","Bavaria","83471","Germany","DE",{"type":49,"coordinates":50},"Point",[51,52],12.98704,47.60055,{"lat":52,"lon":51},[55],{"name":56,"role":36,"phone":57,"phoneExt":24,"email":58},"Tessa Schneeberger, PhD","0049 - 8652 - 932730","tschneeberger@schoen-klinik.de",{"type":33,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"Prof. Dr. Andreas Rembert Koczulla","Principal Investigator","100558033","effects-of-an-automatic-oxygen-titration-system-in-people-with-hypoxemia-during-exercise-training-100558033",false,"NCT06545851","Effects of an Automatic Oxygen Titration System in People With Hypoxemia During Exercise Training","Automatic Oxygen Titration Versus Constant Oxygen Flow Rates During Exercise Training in Hypoxemic People With Chronic Lung Disease - a Randomized, Double-blind, Controlled Cross-over Pilot Study","Inclusion Criteria:\n\n* Chronic lung disease\n* Hypoxemia (pO2\\\u003C 55mmHg) under room air conditions (rest or during exercise) or SpO2\\\u003C88% during exercise\n* established Long-term oxygen therapy or given indication for a Long-term oxygen therapy\u002F supplemental oxygen therapy for exercise\n* Age: 18 to 80 years\n* Participation in an inpatient pulmonary rehabilitation program (Schoen Klinik BGL, Germany)\n* Written informed consent\n\nExclusion Criteria:\n\n\\- Acute exacerbation of underlying pulmonary disease requiring cessation of exercise training.","ALL","18 Years","80 Years",{"count":73,"type":74},15,"ESTIMATED","INTERVENTIONAL",[77],"NA","Long-term oxygen therapy is a fundamental treatment modality for patients with chronic hypoxaemic lung disease. Typically, oxygen is administered at a constant flow rate. However, due to fluctuating activity levels, patients' oxygenation status can vary, potentially leading to oxygen desaturation and increased dyspnoea.\n\nEmerging evidence suggests that automatic oxygen titration - a method of adjusting oxygen flow in response to current oxygen saturation - may have acute advantages over constant oxygen flow.\n\nThe primary objective of this study is to investigate the effect of automatic oxygen titration compared to prescribed constant oxygen flow rates on patients' perceived dyspnoea during exercise endurance training.",[80,81],"Hypoxaemia","Chronic Lung Disease","2024-08-12",{"date":84,"type":85},"2024-08-13","ACTUAL",{"date":87,"type":85},"2023-08-14",{"date":89,"type":74},"2024-11-30",{"name":5,"class":6},1]