[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100429209":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":45,"responsibleParty":62,"collaborators":26,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":71,"eligibilityCriteria":72,"healthyVolunteers":73,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":26,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":26,"overallStatus":47,"whyStopped":26,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"University of Adelaide","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Whey protein preload condition","EXPERIMENTAL","Participants will consume 30 g whey protein isolate powder (dissolved in water) 1-1.5 hr prior to their main evening meal every day for 12 days.",[13],"Dietary Supplement: whey protein",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo condition","PLACEBO_COMPARATOR","Participants will consume an energy-matched mixed-nutrient placebo drink 1-1.5 hr prior to their main evening meal every day for 12 days,",[19],"Dietary Supplement: Placebo",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DIETARY_SUPPLEMENT","whey protein","Protein drink containing 30g whey protein isolate powder (dissolved in water) consumed 1-1.5 hr prior to their main evening meal every day for 12 days, No other advice will be given.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Placebo","Energy-matched mixed-nutrient placebo drink consumed 1-1.5 hr prior to their main evening meal every day for 12 days. No other advice will be given.",[15],[32],{"name":33,"affiliation":5,"role":34},"Amy T Hutchison, PhD","PRINCIPAL_INVESTIGATOR",[36,41],{"name":37,"role":38,"phone":39,"phoneExt":26,"email":40},"Amy Hutchison, PhD","CONTACT","8128 4862","amy.hutchison@adelaide.edu.au",{"name":42,"role":38,"phone":43,"phoneExt":26,"email":44},"Leonie Heilbronn, PhD","8128 4838","leonie.heilbronn@adelaide.edu.au",[46],{"facility":5,"status":47,"city":48,"state":49,"zip":26,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"RECRUITING","Adelaide","South Australia","Australia","AU",{"type":53,"coordinates":54},"Point",[55,56],138.59863,-34.92866,{"lat":56,"lon":55},[59,61],{"name":33,"role":38,"phone":60,"phoneExt":26,"email":40},"+61 8128 4862",{"name":33,"role":38,"phone":26,"phoneExt":26,"email":26},{"type":34,"investigatorFullName":63,"investigatorTitle":64,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"A\u002FProf Leonie Heilbronn","A\u002FProf","100429209","effects-of-an-evening-protein-preload-on-metabolic-health-in-night-shift-workers-propensity-100429209",false,"NCT04869098","Effects of an Evening PROtein PrEload on Metabolic Health in Night ShIfT Workers (PROPENSITy)","Effects of an Evening PROtein PrEload on Blood Glucose, Metabolic Health, and Gut Hormone Release in Night ShIfT Workers (PROPENSITy)","PROPENSITy","Inclusion Criteria:\n\n* Female\n* Night shift workers (with a minimum of 6 months in their current shift work schedule)\n* 35-65 years\n* BMI 28.0-35.0 kg\u002Fm2; waist circumference \\> 80cm\n* Weight stable in the past 6 months\n\nExclusion Criteria:\n\n* Those working standard day time hours only, or those who work less than three to four night shifts per fortnight on average\n* Personal history and\u002For diagnosis of: diabetes, cancer, major psychiatric disorders, liver disease, gastro-intestinal surgery or disease (including malabsorption), eating disorders, anaemia, insomnia or cardiovascular disease, and\u002For any other condition deemed unstable by the study physician\n* Taking medications known to alter body composition or metabolism, including (but not limited to): any medication used to lower blood glucose or antidiabetic medications (metformin, sulfonylureas, Glucagon-like peptide-1 (GLP-1) analogues \\[i.e. exenatide\\], thiazolidinediones or DPP-IV inhibitors \\[i.e. 'gliptins'\\]), medications affecting weight, appetite or gut motility (i.e. diuretics, domperidone, cisapride, orlistat, phentermine, topiramate)\n* Participants who are taking stable doses (i.e. \\> 12 months) of androgenic medications (i.e. testosterone) or SSRI's will not be excluded. Personal history\u002Fdiagnosis (self-reported) of diabetes (type 1 or 2), major psychiatric disorders (schizophrenia, major depressive disorder, bipolar disorder, eating disorders), gastrointestinal disorders, haematological disorders (i.e. thalassemia, iron-deficiency anaemia) insomnia, or any other medical condition, deemed unstable by the study physician\n* Pregnant, planning a pregnancy or breastfeeding\n* Those who have lost or gained \\>5% of body weight in the last 6 months\n* Those who consume four or more standard drinks on a single occasion at a 'daily or almost daily' occurrence\n* current smokers of cigarettes\u002Fmarijuana\u002Fe-cigarettes\u002Fvaporisers\n* unable to comprehend the study protocol (i.e. due to English language or cognitive difficulties)",true,"FEMALE","35 Years","65 Years",{"count":78,"type":79},30,"ESTIMATED","INTERVENTIONAL",[82],"NA","This study will compare the effects of a whey protein supplement or a placebo consumed before the evening meal on health outcomes in night shift workers.",[85,86],"Type 2 Diabetes","Shift-work Disorder","2024-12-18",{"date":89,"type":90},"2024-12-24","ACTUAL",{"date":92,"type":90},"2021-04-27",{"date":94,"type":79},"2026-07-31",{"name":5,"class":6},1]