[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100612333":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":15,"locations":25,"responsibleParty":48,"collaborators":10,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":10,"eligibilityCriteria":57,"healthyVolunteers":58,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":10,"studyType":65,"phases":10,"briefSummary":66,"conditions":67,"keywords":69,"overallStatus":28,"whyStopped":10,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"University of Ljubljana","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Healthy group",null,"Healthy participants without a history of ankle sprain or self-reported ankle instability. Participants will complete the same experimental protocol as the group of chronic ankle instability, including a fatigue protocol of the ankle evertors",{"label":13,"type":10,"description":14,"interventionNames":10},"Chronic ankle instability group","Participants with chronic ankle instability, defined by a history of recurrent ankle sprains and self-reported instability. Participants will complete the same experimental protocol as the control group, including a fatigue protocol of the ankle evertors.",[16,21],{"name":17,"role":18,"phone":19,"phoneExt":10,"email":20},"Alan Kacin, PhD, PT, Prof","CONTACT","+38613001119","alan.kacin@zf.uni-lj.si",{"name":22,"role":18,"phone":23,"phoneExt":10,"email":24},"Tjaž Brezovar","+38640777919","tjaz.brezovar@zf.uni-lj.si",[26],{"facility":27,"status":28,"city":29,"state":10,"zip":30,"country":31,"countryCode":32,"cosmosGeoPoint":33,"geoPoint":38,"contacts":39},"Faculty of Health Sciences","RECRUITING","Ljubljana","1000","Slovenia","SI",{"type":34,"coordinates":35},"Point",[36,37],14.50513,46.05108,{"lat":37,"lon":36},[40,44,46],{"name":41,"role":18,"phone":42,"phoneExt":10,"email":43},"Martina Oder, PhD, Dean","+38613001112","martina.oder@zf.uni-lj.si",{"name":17,"role":45,"phone":10,"phoneExt":10,"email":10},"PRINCIPAL_INVESTIGATOR",{"name":22,"role":47,"phone":10,"phoneExt":10,"email":10},"SUB_INVESTIGATOR",{"type":45,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Alan Kacin","Head of Laboratory","100612333","effects-of-ankle-evertor-fatigue-on-force-sense-and-neuromuscular-activation-in-subjects-with-chronic-ankle-instability-100612333",false,"NCT07252219","Effects of Ankle Evertor Fatigue on Force Sense and Neuromuscular Activation in Subjects With Chronic Ankle Instability","Effects of Ankle Evertor Fatigue on Force Sense and Neuromuscular Activation During Submaximal Isometric Contractions in Individuals With and Without Chronic Ankle Instability","Inclusion criteria for the healthy control group (no CAI):\n\n* Age between 18 and 45 years,\n* No history of injuries or surgical procedures to the lower limbs,\n* No peripheral or central neurological impairments.\n\nInclusion criteria for the chronic ankle instability (CAI) group:\n\n* Age between 18 and 45 years,\n* No history of major surgical procedures on the lower limbs\n* No peripheral or central neurological impairments,\n* Diagnosed chronic ankle instability:\n\n  * First ankle sprain occurred at least one year prior to testing,\n  * At least three months since the most recent ankle sprain,\n  * Subjective feeling of ankle instability - CAIT (Cumberland Ankle Instability Tool) score \\\u003C 24.\n\nExclusion criteria for the CAI group:\n\n\\- Other pathologies of the ankle joint.",true,"ALL","18 Years","45 Years",{"count":63,"type":64},50,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to investigate whether ankle evertor muscle fatigue impairs force perception and alters neuromuscular activation patterns during submaximal isometric contractions, and whether these effects differ between individuals with chronic ankle instability (CAI) and individuals without CAI.",[68],"Chronic Ankle Instability, CAI",[70,71,72,73],"chronic ankle instability","force sense","muscle fatigue","proprioception","2026-04-28",{"date":76,"type":77},"2026-04-29","ACTUAL",{"date":79,"type":77},"2025-05-15",{"date":81,"type":64},"2026-05-04",{"name":5,"class":6},1]