[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100638866":3},{"organization":4,"armGroups":7,"interventions":29,"overallOfficials":34,"centralContacts":43,"locations":49,"responsibleParty":88,"collaborators":90,"id":100,"slug":101,"hasResults":102,"nctId":103,"briefTitle":104,"officialTitle":105,"acronym":34,"eligibilityCriteria":106,"healthyVolunteers":102,"sex":107,"minAge":108,"maxAge":109,"enrollmentInfo":110,"targetDuration":34,"studyType":113,"phases":114,"briefSummary":116,"conditions":117,"keywords":122,"overallStatus":52,"whyStopped":34,"lastUpdateSubmitDate":130,"lastUpdatePostDateStruct":131,"startDateStruct":134,"completionDateStruct":136,"leadSponsor":138,"locationsCount":139},{"fullName":5,"class":6},"Maharishi International University","OTHER",[8,14,20,25],{"label":9,"type":10,"description":11,"interventionNames":12},"B0S0","SHAM_COMPARATOR","Music playlist (control)",[13],"Other: Personalized Music Listening (PML)",{"label":15,"type":16,"description":17,"interventionNames":18},"B1S0","ACTIVE_COMPARATOR","Binaural Beat Music, Music Playlist",[13,19],"Other: Binaural Beat Music (BBM)",{"label":21,"type":16,"description":22,"interventionNames":23},"B0S1","Spatialized Music, Music Playlist",[13,24],"Other: Spatialized Music (SM)",{"label":26,"type":16,"description":27,"interventionNames":28},"B1S1","Binaural Beat Music, Spatialized Music, Music Playlist",[13,19,24],[30,35,39],{"type":6,"name":31,"description":32,"armGroupLabels":33,"otherNames":34},"Personalized Music Listening (PML)","A personlized music playlist is generated by an audio workstation based on text prompts describing prominent musical features for a chosen favourite genre and style. For each entry in the music playlist, acoustic features are extracted from the audio waveforms and higher-level perceptual features are derived that correlate with human emotional and physiological responses to music. A music playlist with a total duration of ±20 minutes is generated for each individual session based on the derived higher-level perceptual features. The selection and slope of a music playlist is adjusted for the time of day by considering the progression of extracted audio features, i.e., an upward slope to increase arousal for morning sessions (AM) and a downward slope to induce a calming effect for afternoon sessions (PM). PML sessions are administered using wireless noise-cancelling headphones and take place in a quiet room with comfortable seating for groups of up to 10 subjects at a time.",[9,21,15,26],null,{"type":6,"name":36,"description":37,"armGroupLabels":38,"otherNames":34},"Binaural Beat Music (BBM)","BBM is the combination of pure tones with a variable carrier frequency embedded in the music playlist recordings. The carrier frequency is adaptive to the music it is combined with. A fixed 10 Hz difference between the carrier frequencies of the left and right headphone channels produces a perceived binaural beat frequency corresponding to an alpha brain-wave pattern associated with relaxation.",[15,26],{"type":6,"name":40,"description":41,"armGroupLabels":42,"otherNames":34},"Spatialized Music (SM)","SM is the presentation of the music playlist such that vocal and instrumental stems are perceived as reverberating within a virtual space from different angles and positions relative to the subject. The music recordings are modified and rendered as a spatialized version using acoustic simulation software.",[21,26],[44],{"name":45,"role":46,"phone":47,"phoneExt":34,"email":48},"Paul Oomen, MMus","CONTACT","+36203980356","poomen@nemolabs.info",[50,72],{"facility":51,"status":52,"city":53,"state":54,"zip":55,"country":56,"countryCode":57,"cosmosGeoPoint":58,"geoPoint":63,"contacts":64},"Woodland Estates Senior Living","RECRUITING","Denver","Colorado","80231","United States","US",{"type":59,"coordinates":60},"Point",[61,62],-104.9847,39.73915,{"lat":62,"lon":61},[65,69],{"name":66,"role":46,"phone":67,"phoneExt":34,"email":68},"Anthony Geiser","303-671-2500","admin@woodlandsl.com",{"name":70,"role":71,"phone":34,"phoneExt":34,"email":34},"Hollie Kemp","PRINCIPAL_INVESTIGATOR",{"facility":73,"status":52,"city":74,"state":54,"zip":75,"country":56,"countryCode":57,"cosmosGeoPoint":76,"geoPoint":80,"contacts":81},"Woodlake Legacy Senior Living","Lakewood","80228",{"type":59,"coordinates":77},[78,79],-105.08137,39.70471,{"lat":79,"lon":78},[82,87],{"name":83,"role":46,"phone":84,"phoneExt":85,"email":86},"Matthew Wistreich","303-237-5700","224","admin@woodlakesl.com",{"name":70,"role":71,"phone":34,"phoneExt":34,"email":34},{"type":89,"investigatorFullName":34,"investigatorTitle":34,"investigatorAffiliation":34,"oldNameTitle":34,"oldOrganization":34},"SPONSOR",[91,94,96,98],{"name":92,"class":93},"Music in the Space Between LLC","UNKNOWN",{"name":95,"class":93},"CoroHealth LLC",{"name":97,"class":93},"Hollie Kemp Consulting LLC",{"name":99,"class":93},"Oxford Health Group LLC","100638866","effects-of-binaural-beats-and-spatialized-music-on-behavioural-and-psychological-symptoms-of-dementia-in-assisted-living-facility-residents-100638866",false,"NCT07626944","Effects of Binaural Beats and Spatialized Music on Behavioural and Psychological Symptoms of Dementia in Assisted Living Facility Residents","Effects of Binaural Beats and Spatialized Music on Behavioural and Psychological Symptoms of Dementia in Assisted Living Facility Residents: A Randomized Controlled Pilot Protocol","Inclusion Criteria:\n\n* (1) age 55-95 years; (2) the subject and\u002For his\u002Fher legal guardian have signed written informed consent; (3) the subject is able to complete the entire trial period; and (4) a minimum of fifty percent of the subjects will have a diagnosis of a dementia condition with a moderate to severe progression.\n\nExclusion Criteria:\n\n* (1) profound hearing loss or impairment; (2) history of seizures, epilepsy (especially sound-induced epilepsy), claustrophobia, or other conditions that put the subject at risk during the trial; (3) physical or mental conditions that may result in inability to complete and\u002For affect the efficacy of assessment.","ALL","55 Years","95 Years",{"count":111,"type":112},120,"ESTIMATED","INTERVENTIONAL",[115],"NA","The purpose of this study is to investigate the effects of Binaural Beat Music (BBM; personalized music playlist with binaural beats), Spatialized Music (SM; personalized and spatialized music playlist), their combination, and possible interaction on older adults in an assisted living community who are either living with a dementia diagnosis or are experiencing typical age-related changes. The control condition is a personalized music playlist without binaural beats and spatialization. It is hypothesized that BBM, SM, and their combination each improve aspects of BPSD compared to controls over a two-week intervention period.\n\nThe Specific Aims of the study are (1) to evaluate whether BBM, SM, and\u002For their combination is superior to control in reducing BPSD severity (primary outcome); (2) to evaluate whether BBM, SM, and\u002For their combination is superior to control in reducing caregiver distress (secondary outcomes); and (3) to evaluate the effects of BBM, SM, and\u002For their combination on improving overall well-being and mood (secondary outcomes).",[118,119,120,121],"BPSD","Caregiver Distress","Well-being","Mood",[123,120,121,119,124,125,126,127,128,129],"Dementia","Personalized Music Listening","Binaural Beat Stimulation","Spatial Audio","Artificial Intelligence","Randomized Controlled Trial","Assisted Living Residences","2026-05-29",{"date":132,"type":133},"2026-06-04","ACTUAL",{"date":135,"type":133},"2026-05-04",{"date":137,"type":112},"2026-06-27",{"name":5,"class":6},2]