[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100557008":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":39,"centralContacts":44,"locations":49,"responsibleParty":69,"collaborators":30,"id":72,"slug":73,"hasResults":74,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":30,"eligibilityCriteria":78,"healthyVolunteers":79,"sex":80,"minAge":81,"maxAge":82,"enrollmentInfo":83,"targetDuration":30,"studyType":86,"phases":87,"briefSummary":89,"conditions":90,"keywords":92,"overallStatus":51,"whyStopped":30,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":105},{"fullName":5,"class":6},"King Abdullah University Hospital","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"First group","ACTIVE_COMPARATOR","Predicat Bioactive desensitizer",[13],"Other: Predicta® Bioactive Desensitizer (PBD, PARKELL, EDGEWOOD, NY, USA)",{"label":15,"type":10,"description":16,"interventionNames":17},"Second group","Gel with 1.23% sodium fluoride",[18],"Other: Gel with 1.23% sodium fluoride (EAZIGEL, VERICOM CO., LTD. SOUTH KOREA)",{"label":20,"type":21,"description":22,"interventionNames":23},"Third group","PLACEBO_COMPARATOR","Placebo gel",[24],"Other: Placebo gel without any active ingredients.",[26,31,35],{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"Predicta® Bioactive Desensitizer (PBD, PARKELL, EDGEWOOD, NY, USA)","A bioactive desensitizer gel that applied on teeth to reduce tooth sensitivity associated with dental bleaching.",[9],null,{"type":6,"name":32,"description":33,"armGroupLabels":34,"otherNames":30},"Gel with 1.23% sodium fluoride (EAZIGEL, VERICOM CO., LTD. SOUTH KOREA)","Fluoride gel that applied on the teeth to reduce tooth sensitivity",[15],{"type":6,"name":36,"description":37,"armGroupLabels":38,"otherNames":30},"Placebo gel without any active ingredients.","Water-based glycerin gel is used as the Placebo gel without active ingredients",[20],[40],{"name":41,"affiliation":42,"role":43},"Ghada A Maghaireh","Jordan University of Science and Technology","PRINCIPAL_INVESTIGATOR",[45],{"name":41,"role":46,"phone":47,"phoneExt":30,"email":48},"CONTACT","0798809296","gmaghair@just.edu.jo",[50],{"facility":42,"status":51,"city":52,"state":30,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"RECRUITING","Irbid","P.O.Box 3030","Jordan","JO",{"type":57,"coordinates":58},"Point",[59,60],35.85,32.55556,{"lat":60,"lon":59},[63,64,67],{"name":41,"role":46,"phone":47,"phoneExt":30,"email":48},{"name":65,"role":66,"phone":30,"phoneExt":30,"email":30},"Hanan J AL-Zriqat","SUB_INVESTIGATOR",{"name":68,"role":66,"phone":30,"phoneExt":30,"email":30},"Majd Y Altarazi",{"type":43,"investigatorFullName":70,"investigatorTitle":71,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"Ghada Maghaireh","Dr.","100557008","effects-of-bio-active-desensitizer-on-reduction-of-tooth-sensitivity-caused-by-in-office-bleaching-100557008",false,"NCT06532526","Effects of Bio-active Desensitizer on Reduction of Tooth Sensitivity Caused by In-office Bleaching.","Assessment of the Effects of Bio-active Desensitizing Materials on the Bleaching Efficacy and Reduction of Tooth Sensitivity Caused by Vital In-office Bleaching: A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* At least eight maxillary anterior teeth present.\n* Age between 18 and 30 years Smokers\n* The selected teeth has a mean shade of C2 or darker (Vitapan Classical, Vita-Zahnfabrik, Sa¨ckingen, Germany)\n* Good general and oral health (no visible plaque or gingivitis)\n* No restorations or carious lesions on the buccal surfaces of the anterior teeth to be whitened\n* No history of tooth sensitivity\n* No use of a desensitizing agent or desensitizing toothpaste in the past six months\n\nExclusion Criteria:\n\n* Active caries and\u002For periodontal diseases (gingivitis and recession) or wasting diseases\n* Smokers\n* Pregnant\u002Flactating women\n* Patients who have bleached their teeth previously\n* No schedule availability",true,"ALL","18 Years","35 Years",{"count":84,"type":85},51,"ESTIMATED","INTERVENTIONAL",[88],"NA","The main aim of this randomized controlled clinical trial is to evaluate the efficacy of a bioactive glass desensitizer in reducing tooth sensitivity associated with in-office vital tooth bleaching. In addition, this study aims to compare the effectiveness of the bioactive glass desensitizer with that of a fluoride gel and a gel without desensitizing agent with regard to incidence, intensity, and duration of tooth sensitivity and, finally, to investigate how these agents affect tooth-shade following in-office bleaching. The hypothesis of the study is: There will be no difference in the effect of a bio-active glass desensitizer on tooth sensitivity associated with vital in-office tooth bleaching compared to a fluoride gel and the bio-active glass desensitizer has no effect on the bleaching efficacy.",[91],"Tooth Discoloration",[93,94,95],"Sensitivity","Bio-active desensitizer","in-office bleaching","2024-07-29",{"date":98,"type":99},"2024-08-01","ACTUAL",{"date":101,"type":99},"2024-07-01",{"date":103,"type":85},"2025-04-01",{"name":5,"class":6},1]