[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100590979":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":60,"collaborators":26,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":26,"eligibilityCriteria":68,"healthyVolunteers":64,"sex":69,"minAge":70,"maxAge":26,"enrollmentInfo":71,"targetDuration":26,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":26,"overallStatus":81,"whyStopped":26,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"The Hong Kong Polytechnic University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"BFR Walking Group","EXPERIMENTAL","Participants in this group will receive blood flow restriction (BFR) walking training. The pressure cuffs will be applied to the proximal thighs. Walking sessions will be conducted on a treadmill at 60% of the participant's maximum walking speed, 3 times per week for 6 weeks. The cuff pressure will begin at 50% of each participant's arterial occlusion pressure (AOP), determined via Doppler ultrasound, and progressively increased every two weeks to a maximum of 200 mmHg.",[13],"Procedure: Blood Flow Restriction (BFR) Walking",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham-BFR Walking Group","SHAM_COMPARATOR","Participants in this group will receive sham blood flow restriction walking training. Pressure cuffs will be applied to the proximal thighs but only inflated to 20 mmHg, which does not restrict blood flow. Walking sessions will be performed under the same treadmill conditions as the BFR group (60% of maximum walking speed, 3 sessions per week for 6 weeks).",[19],"Procedure: Sham Blood Flow Restriction (Sham-BFR) Walking",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Blood Flow Restriction (BFR) Walking","Participants in this group will undergo a supervised treadmill walking program with blood flow restriction (BFR) applied using BFR pressure cuffs. The cuffs are applied to the proximal thighs, and the training pressure starts at 50% of the participant's arterial occlusion pressure (AOP), increasing every two weeks up to 200 mmHg. Walking is performed at 60% of the maximum walking speed, 20 minutes per session, 3 sessions per week for 6 weeks.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Sham Blood Flow Restriction (Sham-BFR) Walking","Participants in this group will follow the same supervised treadmill walking protocol as the BFR group but with minimal cuff pressure (20 mmHg), which does not restrict blood flow. This simulates the sensation of BFR without physiological impact. The purpose is to serve as a placebo comparator. Walking is performed at 60% of maximum walking speed, 20 minutes per session, 3 sessions per week for 6 weeks.",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Yingxiu Diao, Master","CONTACT","+8614796733917","24039355r@connect.polyu.hk",[38],{"facility":39,"status":26,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Hong Kong Polytechnic University","Hung Hom","Kowloon","999077","Hong Kong","HK",{"type":46,"coordinates":47},"Point",[48,49],114.18532,22.30715,{"lat":49,"lon":48},[52,54,58],{"name":33,"role":34,"phone":53,"phoneExt":26,"email":36},"8614796733917",{"name":55,"role":34,"phone":56,"phoneExt":26,"email":57},"Yarou Yuan, Master","90495235","sabrina.yuan@connect.polyu.hk",{"name":33,"role":59,"phone":26,"phoneExt":26,"email":26},"SUB_INVESTIGATOR",{"type":61,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100590979","effects-of-blood-flow-restriction-training-on-muscle-strength-and-physical-function-for-stroke-related-sarcopenia-100590979",false,"NCT06974461","Effects of Blood Flow Restriction Training on Muscle Strength and Physical Function for Stroke-Related Sarcopenia","Effects of Blood Flow Restriction Training on Muscle Strength and Physical Function in Individuals With Stroke-Related Sarcopenia: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Diagnosed with chronic stroke (≥6 months post-stroke)\n* Diagnosed with sarcopenia, based on AWGS 2019 criteria\n\nExclusion Criteria:\n\n* Stroke occurred within the past 6 months\n* Resting systolic blood pressure \\> 200 mmHg\n* Resting diastolic blood pressure \\> 100 mmHg\n* Presence of implanted electronic or metallic devices that interfere with blood flow restriction cuffs\n* Contraindication to bioelectrical impedance analysis (e.g., pacemaker, ICD)","ALL","50 Years",{"count":72,"type":73},64,"ESTIMATED","INTERVENTIONAL",[76],"NA","Effects of Blood Flow Restriction Walking on Muscle Strength and Physical Function in Chronic Stroke Patients with Sarcopenia: A Randomized, Sham-Controlled Trial Primary Objective: To evaluate the effects of BFR walking on muscle strength and physical function in chronic stroke patients with sarcopenia, compared to sham-BFR walking.\n\nSecondary Objective: (1) To explore the potential impact of BFR walking on muscle mass and vascular function in chronic stroke patients with sarcopenia. (2) To assess the influence of BFR walking on quality of life in chronic stroke patients with sarcopenia.",[79,80],"Sarcopenia","Chronic Stroke Patients","NOT_YET_RECRUITING","2025-05-07",{"date":84,"type":85},"2025-05-16","ACTUAL",{"date":87,"type":73},"2025-05-15",{"date":89,"type":73},"2027-12-28",{"name":5,"class":6},1]