[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100511678":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":41,"responsibleParty":55,"collaborators":57,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":26,"eligibilityCriteria":66,"healthyVolunteers":62,"sex":67,"minAge":68,"maxAge":26,"enrollmentInfo":69,"targetDuration":26,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":81,"overallStatus":89,"whyStopped":26,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"The Nethersole School of Nursing","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Cognitive behavioural therapy-based(CBT-based) intervention group","EXPERIMENTAL","A specifically designed CBT-based intervention consisting of 8 weekly sessions will be conducted in a group format.",[13],"Behavioral: Cognitive behavioural therapy-based intervention",{"label":15,"type":16,"description":17,"interventionNames":18},"Control group","ACTIVE_COMPARATOR","Participants will receive eight health education sessions simultaneously with the CBT-based intervention group.",[19],"Behavioral: Educational group",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Cognitive behavioural therapy-based intervention","A specifically designed CBT-based intervention consisting of 8 weekly sessions with group format.\n\nEach group will be comprised of 4-10 participants, and each session will last 1.5 hours.\n\nThe content of the weekly sessions will be based on Beck's cognitive theory and the cognitive therapy in groups guidelines.\n\nThe framework of every session will follow a pre-determined structure.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Educational group","The educational sessions are consisting of 8 weekly sessions with a group format. These sessions will focus on cancer-related information and care knowledge which will be delivered in daily routine care.",[15],[32],{"name":33,"affiliation":34,"role":35},"Hua Yin","Chinese University of Hong Kong","PRINCIPAL_INVESTIGATOR",[37],{"name":33,"role":38,"phone":39,"phoneExt":26,"email":40},"CONTACT","+8613823013393","huayin0408@163.com",[42],{"facility":43,"status":26,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":26},"Zhuhai People's Hospital","Zhuhai","Guangdong","519000","China","CN",{"type":50,"coordinates":51},"Point",[52,53],113.56778,22.27694,{"lat":53,"lon":52},{"type":35,"investigatorFullName":33,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Principal Investigator",[58],{"name":59,"class":6},"ZhuHai Hospital","100511678","effects-of-cbt-based-intervention-among-patients-with-liver-cancer-100511678",false,"NCT05942560","Effects of CBT-Based Intervention Among Patients With Liver Cancer","Effects of Cognitive Behavioral Therapy-Based Intervention on Depression, Anxiety, Quality of Life, Immune Indicators, and Survival Among Patients With Liver Cancer","Inclusion Criteria:\n\n1. Adults (aged ≥18);\n2. Diagnosed with liver cancer based on pathological findings or imaging findings in the medical record;\n3. The severity level of depression and anxiety: Depression \\> 7 using HAD-D, or Anxiety \\> 7 using HAD-A (Hospital Anxiety and Depression Scale, HADS; HAD-D, Hospital Depression Scale; HAD-A, Hospital Anxiety Scale).\n\nExclusion Criteria:\n\n1. Patients who are taking part in another psychological intervention clinical trial or consented to receive another psychotherapy, suffered from aphasia and other communication difficulties will be excluded from the study\n2. Patients with active immunological diseases, such as autoimmune diseases, and inflammatory diseases.\n3. Patients accepting hormone therapy or taking long-term antibiotic drugs.\n4. Patients who lack the basic ability of understanding and expression and are incompetent in giving consent.","ALL","18 Years",{"count":70,"type":71},160,"ESTIMATED","INTERVENTIONAL",[74],"NA","This study investigates the effects of a CBT- based intervention on depression, anxiety, immune function, quality of life, and overall survival. It also explores if the effects of the intervention on immune function and quality of life are mediated through the improvements in depression and anxiety among patients with liver cancer.",[77,78,79,80],"Depression","Anxiety","Liver Cancer","CBT",[82,83,84,85,86,87,88],"cognitive behavioural therapy","depression","anxiety","immune","quality of life","survival","liver cancer","NOT_YET_RECRUITING","2023-11-21",{"date":92,"type":93},"2023-11-22","ACTUAL",{"date":95,"type":71},"2023-12-30",{"date":97,"type":71},"2029-06-30",{"name":5,"class":6},1]