[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100639028":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":35,"locations":25,"responsibleParty":41,"collaborators":25,"id":45,"slug":46,"hasResults":47,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":25,"eligibilityCriteria":51,"healthyVolunteers":52,"sex":53,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":25,"studyType":59,"phases":60,"briefSummary":62,"conditions":63,"keywords":65,"overallStatus":70,"whyStopped":25,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":25},{"fullName":5,"class":6},"National Taiwan University Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"rhythmic breathing exercise group","EXPERIMENTAL","The rhythmic breathing exercise group will perform 10 minutes of thoracic expansion exercises followed by 15 minutes of progressive diaphragmatic breathing (4-s inhalation\u002F6-s exhalation) to facilitate parasympathetic dominance.",[13],"Other: thoracic expansion exercises and slow diaphragmatic breathing",{"label":15,"type":16,"description":17,"interventionNames":18},"natural breathing exercise group","SHAM_COMPARATOR","The natural breathing exercise group performed sham thoracic expansion exercises and sham slow diaphragmatic breathing",[19],"Other: Sham Block",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"thoracic expansion exercises and slow diaphragmatic breathing","4-week supervised training program, consisting of three 30-minute sessions per week. Thoracic expansion exercises consists of chest wall stretching and mobility drills. Followed by 15 minutes of progressive slow diaphragmatic breathing (4-s inhalation\u002F6-s exhalation).",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Sham Block","During sham TEE, participants perform comfortable thoracic movements without foam rollers or specific breathing coordination. During sham SDB, they maintain a spontaneous, natural respiratory rhythm in relaxed postures. Crucially, the sham protocol lacks the rhythmic pacing (4:6s), diaphragmatic depth cues, and resistance-based progression required to trigger the neuro-cognitive \"respiratory-brain\" axis.",[15],[31],{"name":32,"affiliation":33,"role":34},"Yan Ci Liu","School and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University","PRINCIPAL_INVESTIGATOR",[36],{"name":37,"role":38,"phone":39,"phoneExt":25,"email":40},"Yun Syuan Lin","CONTACT","+886 986161796","b11408046@ntu.edu.tw",{"type":42,"investigatorFullName":43,"investigatorTitle":44,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"SPONSOR_INVESTIGATOR","National Taiwan University Clinical Trial Center","Undergraduate Student","100639028","effects-of-combined-thoracic-and-diaphragmatic-breathing-on-cognitive-and-psycho-physiological-functions-100639028",false,"NCT07620249","Effects of Combined Thoracic and Diaphragmatic Breathing on Cognitive and Psycho-Physiological Functions","The Effects of Combined Thoracic Expansion Exercises and Slow Diaphragmatic Breathing on Cognitive Function, Brain Activation, Psychological Status, and Head-Shoulder Posture in Healthy Adults","Inclusion Criteria:\n\n1. age between 18 to 30 years with at least a high school education to ensure baseline cognitive task comprehension\n2. the ability to adhere to verbal instructions\n3. no regular participation in formal breathing exercise or mindfulness training within the past six months.\n\nExclusion Criteria:\n\n1. a history of musculoskeletal, cardiovascular, or cerebrovascular diseases which may interfere this study\n2. history of respiratory disease or recent respiratory infection\n3. diabetes mellitus with neuropathy, peripheral neuropathy, or other neurological disorders\n4. major surgery within the past six months\n5. Current or past major psychiatric disorders or cognitive impairment\n6. use of medications significantly affecting cerebral hemodynamics or autonomic function (e.g., beta-blockers, vasodilators) within the past 2 weeks\n7. use of psychotropic medications or substances known to alter cerebral blood flow, neural activation, or autonomic regulation (e.g., antidepressants, antipsychotics, anxiolytics, stimulants, or sedative-hypnotics).",true,"ALL","18 Years","30 Years",{"count":57,"type":58},60,"ESTIMATED","INTERVENTIONAL",[61],"NA","This study aims to investigate the effects of a combined thoracic expansion exercise (TEE) and slow diaphragmatic breathing (SDB) program on cognitive function, brain activation, psychological status, and head-shoulder posture in healthy young adults.",[64],"Diaphragm Pacing",[66,67,68,69],"breathing exercise","autonomic regulation","cognitive function","functional near-infrared spectroscopy","NOT_YET_RECRUITING","2026-05-27",{"date":73,"type":74},"2026-06-02","ACTUAL",{"date":76,"type":58},"2026-05-25",{"date":78,"type":58},"2027-02-01",{"name":43,"class":6}]