[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100410757":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":33,"centralContacts":38,"locations":44,"responsibleParty":62,"collaborators":42,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":42,"eligibilityCriteria":72,"healthyVolunteers":68,"sex":73,"minAge":74,"maxAge":75,"enrollmentInfo":76,"targetDuration":42,"studyType":79,"phases":80,"briefSummary":82,"conditions":83,"keywords":42,"overallStatus":46,"whyStopped":42,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Attikon Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"DEX group","ACTIVE_COMPARATOR","Dexmedetomidine given at a bolus dose of 1,0 μg\u002Fkg 10min before induction of anesthesia and then after as a continuous infusion 0,4-0,8 μg\u002Fkg\u002Fh until the end of the surgery.",[13],"Drug: Dexmedetomidine",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo group","PLACEBO_COMPARATOR","Normal saline given as a bolus dose 10min before induction of anesthesia and then after as a continuous infusion until the end of the surgery.",[19],"Other: Normal Saline",[21,28],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Dexmedetomidine","Administration",[9],[27],"Dexmed",{"type":6,"name":29,"description":24,"armGroupLabels":30,"otherNames":31},"Normal Saline",[15],[32],"Saline",[34],{"name":35,"affiliation":36,"role":37},"Paraskevi Matsota, Prof","2nd Department of Anesthesiology, Attikon University Hospital","STUDY_CHAIR",[39],{"name":35,"role":40,"phone":41,"phoneExt":42,"email":43},"CONTACT","6945544563",null,"matsota@yahoo.gr",[45],{"facility":36,"status":46,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"RECRUITING","Athens","Attica","12462","Greece","GR",{"type":53,"coordinates":54},"Point",[55,56],23.72784,37.98376,{"lat":56,"lon":55},[59],{"name":60,"role":40,"phone":61,"phoneExt":42,"email":43},"Paraskevi Matsota, MD, PhD","+30210583100",{"type":63,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":42,"oldOrganization":42},"PRINCIPAL_INVESTIGATOR","Paraskevi Matsota","Prof of Anaesthesiology","100410757","effects-of-dexmedetomidine-on-intraocular-pressure-during-scheduled-spine-surgeries-100410757",false,"NCT04628663","Effects of Dexmedetomidine on Intraocular Pressure During Scheduled Spine Surgeries","Effects of Systemic Administration of Dexmedetomidine on Intraocular Pressure During Scheduled Spine Surgeries in a Prone Position. Prospective, Randomized, Double-blinded Study.","Inclusion Criteria:\n\n* Adult patients undergoing scheduled spine surgery performed in prone position under general anaesthesia\n\nExclusion Criteria:\n\n* Patients who refuse to be a part of the study\n* Patients with previous eye surgery\n* Preexisting eye disease (e.g glaucoma)\n* Allergy to the study drug or any drug which is in the trial\n* Preoperative unstable hemodynamics","ALL","18 Years","90 Years",{"count":77,"type":78},60,"ESTIMATED","INTERVENTIONAL",[81],"NA","The aim of this study is to examine the effects of intraoperative systemic use of dexmedetomidine on the intraocular pressure (IOP) in patients undergoing spine surgeries in a prone position under general anesthesia.",[84],"Intraocular Pressure","2025-09-29",{"date":87,"type":88},"2025-09-30","ACTUAL",{"date":90,"type":88},"2021-03-20",{"date":92,"type":78},"2026-05",{"name":5,"class":6},1]