[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100638489":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":32,"centralContacts":36,"locations":31,"responsibleParty":41,"collaborators":31,"id":43,"slug":44,"hasResults":45,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":31,"eligibilityCriteria":49,"healthyVolunteers":45,"sex":50,"minAge":51,"maxAge":52,"enrollmentInfo":53,"targetDuration":31,"studyType":56,"phases":57,"briefSummary":59,"conditions":60,"keywords":62,"overallStatus":64,"whyStopped":31,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":31},{"fullName":5,"class":6},"Riphah International University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"NMES + Standard Cardiac Rehabilitation","EXPERIMENTAL","Participants in this group will receive combined diaphragmatic and abdominal neuromuscular electrical stimulation (NMES) in addition to standard cardiac rehabilitation. NMES will be applied using surface electrodes placed over the lower thoracic region (for diaphragmatic stimulation) and abdominal muscles (rectus abdominis and external obliques). The intervention will be delivered for 30 minutes per session, five days per week, for two weeks, along with routine cardiac rehabilitation including aerobic exercise, breathing exercises, and education.",[13],"Device: Neuromuscular Electrical Stimulation (NMES)",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard Cardiac Rehabilitation","ACTIVE_COMPARATOR","Participants in this group will receive standard cardiac rehabilitation only, including aerobic exercise, breathing exercises, and patient education as per institutional protocol, without the use of neuromuscular electrical stimulation (NMES).",[19],"Other: Standard Cardiac Rehabilitation",[21,28],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Neuromuscular Electrical Stimulation (NMES)","A dual-channel electrical stimulation device will be used to deliver stimulation to respiratory muscles. Surface electrodes will be placed over the lower thoracic region for diaphragmatic stimulation and over the abdominal muscles for expiratory muscle stimulation. Stimulation parameters will include a frequency of 30-50 Hz, pulse width of 300 µs, and a duty cycle of 5 seconds on and 5 seconds off. Intensity will be adjusted to achieve visible muscle contraction without discomfort. Sessions will last 30 minutes, five days per week, for two weeks.",[9],[27],"Diaphragmatic NMES; Abdominal NMES",{"type":6,"name":15,"description":29,"armGroupLabels":30,"otherNames":31},"A structured cardiac rehabilitation program including aerobic exercise, breathing exercises, and patient education delivered according to institutional protocols, without the use of neuromuscular electrical stimulation.",[15],null,[33],{"name":34,"affiliation":5,"role":35},"Arjumand Bano, MS","PRINCIPAL_INVESTIGATOR",[37],{"name":34,"role":38,"phone":39,"phoneExt":31,"email":40},"CONTACT","+92 305 9551883","arjumand.bano@riphah.edu.pk",{"type":42,"investigatorFullName":31,"investigatorTitle":31,"investigatorAffiliation":31,"oldNameTitle":31,"oldOrganization":31},"SPONSOR","100638489","effects-of-diaphragmatic-and-abdominal-neuromuscular-electrical-stimulation-in-post-pci-patients-100638489",false,"NCT07629037","Effects of Diaphragmatic and Abdominal Neuromuscular Electrical Stimulation in Post-PCI Patients","Effects of Diaphragmatic and Abdominal Neuromuscular Electrical Stimulation on Arterial Blood Gases, Pulmonary Function, Ejection Fraction and Functional Capacity in Post-PCI Patients","Inclusion Criteria:\n\n* Patients aged 40-75 years\n* Patients who have undergone successful percutaneous coronary intervention (PCI) for stable or acute coronary syndrome\n* Hemodynamically stable (no inotropic support, no active arrhythmias)\n* Left ventricular ejection fraction (LVEF) ≥ 35%\n* Able to perform spirometry and 6-minute walk test (6MWT)\n* Willing to participate and provide informed consent\n\nExclusion Criteria:\n\n* Significant arrhythmias or pacemaker\u002Fimplantable defibrillator not cleared for NMES\n* Severe pulmonary disease (e.g., advanced COPD, pulmonary fibrosis) affecting lung function independently\n* Neuromuscular disorders interfering with NMES application\n* Recent stroke or severe cognitive impairment limiting participation\n* Active infection, sepsis, or systemic inflammatory disease","ALL","40 Years","75 Years",{"count":54,"type":55},42,"ESTIMATED","INTERVENTIONAL",[58],"NA","This study is a randomized controlled trial designed to evaluate the effects of combined diaphragmatic and abdominal neuromuscular electrical stimulation (NMES) on arterial blood gases, pulmonary function, left ventricular ejection fraction, and functional capacity in patients following percutaneous coronary intervention (PCI). A total of 42 participants will be randomly allocated into two groups: an intervention group receiving NMES along with standard cardiac rehabilitation, and a control group receiving standard rehabilitation alone. The intervention will be administered for 30 minutes per session, five days per week, over a period of two weeks. Outcome measures will include arterial blood gas parameters (PaO₂, PaCO₂, SaO₂), spirometry indices (FVC, FEV₁, PEFR), ejection fraction assessed by echocardiography, and functional capacity measured using the 6-minute walk test. Assessments will be conducted at baseline and post-intervention. The study aims to determine whether NMES can serve as an effective adjunct to conventional cardiac rehabilitation in improving respiratory and functional outcomes in post-PCI patients.",[61],"Percutaneous Coronary Intervention",[63],"Cardiac Rehab Coronary Stent","NOT_YET_RECRUITING","2026-06-01",{"date":67,"type":68},"2026-06-05","ACTUAL",{"date":70,"type":55},"2026-05-28",{"date":72,"type":55},"2026-06-29",{"name":5,"class":6}]