[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100626191":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":38,"centralContacts":55,"locations":66,"responsibleParty":79,"collaborators":29,"id":83,"slug":84,"hasResults":85,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":29,"eligibilityCriteria":89,"healthyVolunteers":85,"sex":90,"minAge":91,"maxAge":92,"enrollmentInfo":93,"targetDuration":29,"studyType":96,"phases":97,"briefSummary":99,"conditions":100,"keywords":103,"overallStatus":69,"whyStopped":29,"lastUpdateSubmitDate":109,"lastUpdatePostDateStruct":110,"startDateStruct":113,"completionDateStruct":115,"leadSponsor":117,"locationsCount":118},{"fullName":5,"class":6},"Hacettepe University","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Aerobic exercise group","EXPERIMENTAL","Aerobic exercise training will be applied 3 days a week for 3 months and each participant will participate in a total of 36 exercise sessions individually.",[13],"Other: Aerobic exercise",{"label":15,"type":10,"description":16,"interventionNames":17},"Strengthening exercise group","Strengthening exercise training will be applied 3 days a week for 3 months and each participant will participate in a total of 36 exercise sessions individually.",[18],"Other: Strengthening exercise",{"label":20,"type":6,"description":21,"interventionNames":22},"Posture and stretching exercise group","Posture and stretching exercise training will be applied 3 days a week for 3 months and each participant will participate in a total of 36 exercise sessions individually as the control intervention.",[23],"Other: Posture and strentching exercise",[25,30,34],{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":29},"Aerobic exercise","Participants will receive a total of 36 sessions of treatment, 3 sessions per week for 12 weeks. Aerobic exercise training will be performed with a bicycle ergometer, and a 5-minute warm-up (pedaling without resistance) program will be applied before the exercise training, finished by a 5-minute cool-down program (pedaling without resistance). Details of the intervention is described below:\n\n60% of maximum heart rate, for 30 minutes (1-2nd weeks), 60% of maximum heart rate, for 45 minutes (3-4th weeks), 60% of maximum heart rate, for 60 minutes (5-6th weeks), mid-examination (at the end of the 6th week), 75% of maximum heart rate, for 30 minutes (7-8th weeks), 75% of maximum heart rate, for 45 minutes (9-10th weeks), 75% of maximum heart rate, for 60 minutes (11-12th weeks)",[9],null,{"type":6,"name":31,"description":32,"armGroupLabels":33,"otherNames":29},"Strengthening exercise","A 5-minute warm-up (neck and upper extremity range of motion exercises) will be applied before the exercise training, and finished by a 5-minute cool-down program (neck and upper extremity range of motion exercises). Details of the intervention is described below: Isometric neck exercise (MVC 80%,2x10) and Theraband resistive neck and upper body exercises 10 RM-2x10 (1-2nd weeks), Isometric neck exercise (MVC 80%,3x10) and Theraband resistive neck and upper body exercises 10 RM-3x10 (3-4th weeks), Isometric neck exercise (MVC 80%,3x15) and Theraband resistive neck and upper body exercises 10 RM-3x15 (5-6th weeks) , mid-examination (6th week), Isometric neck exercise (MVC 80%,2x10) Theraband resistive neck and upper body exercises 10 RM-2x10 (7-8th weeks), Isometric neck exercise (MVC 80%,3x10) Theraband resistive neck and upper body exercises 10 RM-3x10 (9-10th weeks), Isometric neck exercise (MVC 80%,3x15) Theraband resistive neck and upper body exercises 10 RM-3x15 (11-12th weeks)",[15],{"type":6,"name":35,"description":36,"armGroupLabels":37,"otherNames":29},"Posture and strentching exercise","Posture and stretching exercises and stretching exercises will be applied as a control treatment to volunteers with chronic neck pain included in the control group, and at the end of the study, these people will be included in the training program according to the exercise approach that is effective.",[20],[39,43,46,49,52],{"name":40,"affiliation":41,"role":42},"Ahmet Ilkay Isikay, Associate Professor","Faculty of Medicine, Department of Neurosurgery, Hacettepe University","STUDY_CHAIR",{"name":44,"affiliation":45,"role":42},"Asli Pinar, Professor","Faculty of Medicine, Department of Medical Biology, Hacettepe University",{"name":47,"affiliation":48,"role":42},"Ezgi Yetim Arsava, PhD","Faculty of Medicine, Department of Neurology, Hacettepe University",{"name":50,"affiliation":51,"role":42},"Erdem Karabulut, Professor","Faculty of Medicine, Department of Biostatistics, Hacettepe University",{"name":53,"affiliation":54,"role":42},"Rahsan Gocmen, Associate Professor","Faculty of Medicine, Department of Radiology, Hacettepe University",[56,62],{"name":57,"role":58,"phone":59,"phoneExt":60,"email":61},"Zeynep Güven, MsC","CONTACT","90+3123052525","130","fztzeynepguven@gmail.com",{"name":63,"role":58,"phone":64,"phoneExt":60,"email":65},"Songul Atasavun-Uysal, Professor","+903123052525","songula@hacettepe.edu.tr",[67],{"facility":68,"status":69,"city":70,"state":71,"zip":29,"country":72,"countryCode":29,"cosmosGeoPoint":73,"geoPoint":78,"contacts":29},"Hacettepe University Faculty of Physical Therapy and Rehabilitation","RECRUITING","Ankara","Altindag","Turkey (Türkiye)",{"type":74,"coordinates":75},"Point",[76,77],32.85427,39.91987,{"lat":77,"lon":76},{"type":80,"investigatorFullName":81,"investigatorTitle":82,"investigatorAffiliation":5,"oldNameTitle":29,"oldOrganization":29},"PRINCIPAL_INVESTIGATOR","Songül Atasavun UYSAL","Professor","100626191","effects-of-different-exercise-protocols-on-physical-and-cognitive-changes-in-people-with-chronic-neck-pain-100626191",false,"NCT07432425","Effects of Different Exercise Protocols on Physical and Cognitive Changes in People With Chronic Neck Pain","Effects of Different Exercise Protocols on Physical Status, Cognitive Functions, Brain Structure, and Blood Biomarkers in People With Chronic Neck Pain","Inclusion Criteria:\n\n* Participants aged 20-65\n* Having neck pain at least 3 months and rated as 3 or more according to the Numeric Rating Scale\n* Having a score of 10 or more according to the Neck Disability Index\n* Having a score of 24 or above according to the Mini Mental State Examination\n* Right hand dominancy according to Edinburgh Handedness Inventory\n* Having at least a primary school graduate\n\nExclusion Criteria:\n\n* Having neuropsychiatric, neurologic, metabolic, cardiovascular, and inflammatory disease(s)\n* Participating in a rehabilitation program for neck pain in the last 6 months\n* Having an exercise or sports history of 6 months or more\n* Presence of brain parenchymal lesion on MRI\n* Presence of materials in the body such as jewelry, metal, hearing aid, pacemaker, lead that cannot be removed and are not suitable for MRI\n* History of neck or shoulder surgery\n* Being pregnant or having given birth within the last year","ALL","20 Years","65 Years",{"count":94,"type":95},21,"ESTIMATED","INTERVENTIONAL",[98],"NA","This study aims to investigate the effects of different exercise approaches on physical status, cognitive functions, brain structures, and blood biomarkers in individuals with chronic neck pain.",[101,102],"Neck Pain","Chronic Neck Pain",[101,104,105,106,107,108],"Exercise","Cognition","Neuropsychological test","Neuroimaging","Enzyme-linked immunosorbent assay","2026-02-19",{"date":111,"type":112},"2026-02-25","ACTUAL",{"date":114,"type":112},"2025-05-01",{"date":116,"type":95},"2026-03-30",{"name":5,"class":6},1]