[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100631909":3},{"organization":4,"armGroups":7,"interventions":27,"overallOfficials":33,"centralContacts":37,"locations":42,"responsibleParty":61,"collaborators":64,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":12,"eligibilityCriteria":74,"healthyVolunteers":70,"sex":75,"minAge":76,"maxAge":77,"enrollmentInfo":78,"targetDuration":12,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":87,"overallStatus":92,"whyStopped":12,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"Xinhua Hospital, Shanghai Jiao Tong University School of Medicine","OTHER",[8,13,19,23],{"label":9,"type":10,"description":11,"interventionNames":12},"control group","NO_INTERVENTION","Control group will receive no music therapy intervention outside of routine daily care.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Music therapy group I","EXPERIMENTAL","Music therapy group I will receive music at a speed of 40-50 beats\u002Fmin. Each music therapy group will receive therapy in the form of the same set of four music suites in the same melodic style and rhythm.",[18],"Behavioral: Music Therapy",{"label":20,"type":15,"description":21,"interventionNames":22},"Music Therapy Group II","Music therapy group II will receive music at 60-100 beat\u002Fmin. Each music therapy group will receive therapy in the form of the same set of four music suites in the same melodic style and rhythm.",[18],{"label":24,"type":15,"description":25,"interventionNames":26},"Music Therapy Group III","Music therapy group III will receive music at 110-160 beats\u002Fmin. Each music therapy group will receive therapy in the form of the same set of four music suites in the same melodic style and rhythm.",[18],[28],{"type":29,"name":30,"description":31,"armGroupLabels":32,"otherNames":12},"BEHAVIORAL","Music Therapy","The intervention will be conducted while the infants are hospitalized, 30 minutes before morning and afternoon feeds. The intervention sessions will last for 20 minutes per session. During the treatment, the same therapist, in the same order, and with the same instrument, will in turn play the four repertoires to each of the three intervention groups.",[20,24,14],[34],{"name":35,"affiliation":5,"role":36},"Yongjun Zhang, Dr","PRINCIPAL_INVESTIGATOR",[38],{"name":35,"role":39,"phone":40,"phoneExt":12,"email":41},"CONTACT","8625078999","zhangyongjun@xinhuamed.com.cn",[43],{"facility":44,"status":12,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine","Shanghai","Shanghai Municipality","200000","China","CN",{"type":51,"coordinates":52},"Point",[53,54],121.45806,31.22222,{"lat":54,"lon":53},[57],{"name":58,"role":39,"phone":59,"phoneExt":12,"email":60},"Jingwen Lyu, Doctor","+86-021-25078335","jingwen_lv@163.com",{"type":36,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"Yongjun Zhang","Professor",[65],{"name":66,"class":67},"Shanghai Conservatory of Music","UNKNOWN","100631909","effects-of-different-music-tempos-on-feeding-outcomes-in-preterm-infants-100631909",false,"NCT07506811","Effects of Different Music Tempos on Feeding Outcomes in Preterm Infants","Effects of Different Music Tempos on Feeding Outcomes in Preterm Infants: a Randomized Open-label Parallel-controlled Trial Protocol","Inclusion Criteria:\n\n* Preterm infants of gestational age ≥32 weeks or corrected gestational age ≥32 weeks\n* Admitted to hospital within 24 hours after birth\n* Apgar score ≥8 points\n* Normal auditory function according to examination of brainstem auditory evoked potential\n\nExclusion Criteria:\n\n* Congenital system defects including congenital heart disease, nervous system malformations, diaphragmatic hernias, gastrointestinal malformations\n* Serious complications, such as intracranial hemorrhage, respiratory failure, or serious infection, and those requiring mechanical ventilation","ALL","32 Weeks","37 Weeks",{"count":79,"type":80},284,"ESTIMATED","INTERVENTIONAL",[83],"NA","Background Newborns perceive the world through sound, and music therapy in the neonatal intensive care unit has been shown to have significant benefits in terms of heart rate, oxygen saturation, sucking\u002Ffeeding capacity, and length of hospital stay. However, it is still unclear what kind of music therapy can better promote early extrauterine growth in preterm infants, and further exploration and practice are needed. Music therapy is an emerging interdisciplinary discipline that integrates musicology, medicine, and psychology. In the uterine environment, the most important rhythmic sounds that the fetus can hear is the mother's heartbeat, as well as the fetus's own heartbeat. The maternal heart rate ranges from 60 to 100 beats\u002Fmin, and the corresponding speed of 60-100 beats\u002Fmin in music is medium speed. The fetal heart rate is 110-160 beats\u002Fmin, and the corresponding speed of 110-160 beats\u002Fmin in music is considered fast. Music slower than 40-50 beats\u002Fmin is slow. The primary objective of this study is to investigate the effect of music therapy at different music speeds in preterm infants, at the time to full enteral feeding.\n\nMethods This is a single-center, randomized, open-label, parallel-controlled trial including 284 preterm newborns with gestational age or corrected gestational age ≥32 weeks admitted into the neonatal intensive care unit. The infants will be randomly allocated to receive music I, II, III or control therapy. The music therapy is provided with the same music in three different tempos: 40-50 beats\u002Fmin, 60-100 beats\u002Fmin, and 110-160 beats\u002Fmin, by two professional licensed music therapists using the same instrument and singing, before morning and afternoon feeding time every day during hospitalization. The primary outcome is the time to achieving full enteral feeding. The secondary outcomes include sucking\u002Ffeeding capacity, physical growth rate, complications, length of hospital stay, behavior state (Test of Infant Motor Performance (TIMP), Bayley III Infant Development Scale), and brain imaging (resting functional magnetic resonance imaging).\n\nHypothesis:\n\nThe investigator expect that either music therapy applied at 40-50 beats\u002Fmin or 110-160 beats\u002Fmin will result in early full enteral feeding, and reductions in length of hospital stay and complications in preterm infants.",[86],"Music",[88,89,90,91],"preterm infant","feeding","Music therapy","music speed","NOT_YET_RECRUITING","2026-03-28",{"date":95,"type":96},"2026-04-02","ACTUAL",{"date":98,"type":80},"2026-09-20",{"date":100,"type":80},"2029-07-31",{"name":5,"class":6},1]