[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100637233":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":29,"locations":35,"responsibleParty":52,"collaborators":25,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":25,"eligibilityCriteria":61,"healthyVolunteers":57,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":25,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":75,"overallStatus":38,"whyStopped":25,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Sun Yat-sen University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"cancer patients who undergo PICC placement using two-needle tunnel technique","ACTIVE_COMPARATOR","Two-needle tunnel PICC procedure:\n\n1. Local anesthesia at puncture and catheter exit sites;\n2. Ultrasound-guided vascular puncture at puncture site, guide wire inserted via puncture needle;\n3. Skin dilation at both puncture and exit sites;\n4. 4cm saline tunnel created with 0.9% NaCl: 10mL syringe advanced along tunnel path while injecting solution;\n5. Subcutaneous tunnel formed from exit site to puncture site with tunneling tool, catheter pulled through tunnel to puncture site;\n6. Vascular sheath inserted over guide wire, catheter trimmed to length, advanced through sheath after guide wire removal;\n7. Vascular sheath peeled off, catheter adjusted to proper position;\n8. Catheter tip position confirmed;\n9. Puncture site closed with suture-free tape, both sites covered with sterile dressings, catheter secured.",[13],"Other: two-needle tunnel technique",{"label":15,"type":16,"description":17,"interventionNames":18},"cancer patients who undergo PICC placement using one-needle tunnel technique","EXPERIMENTAL","Ultrasound guidance is used for vascular puncture and assisted subcutaneous tunnel creation:\n\n1. Local anesthesia is administered at the puncture site，the puncture needle travels 4 cm through the subcutaneous tissue before entering the blood vessel;\n2. The guide wire is inserted along the puncture needle;\n3. skin dilation;\n4. The vascular sheath is advanced into the blood vessel via the guide wire, and the catheter is inserted through the vascular sheath;\n5. The catheter tip position is confirmed, and the catheter is secured.",[19],"Other: One-needle tunnel technique",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"One-needle tunnel technique","1. Local anesthesia is administered at the puncture site，Ultrasound guidance is used for vascular puncture and assisted subcutaneous tunnel creation，the puncture needle travels 4 cm through the subcutaneous tissue before entering the blood vessel;\n2. The guide wire is inserted along the puncture needle;\n3. skin dilation;\n4. The vascular sheath is advanced into the blood vessel via the guide wire, and the catheter is inserted through the vascular sheath;\n5. The catheter tip position is confirmed, and the catheter is secured.",[15],null,{"type":6,"name":27,"description":11,"armGroupLabels":28,"otherNames":25},"two-needle tunnel technique",[9],[30],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},"Zeyin Hu","CONTACT","15899954190","huzy@sysucc.org.cn",[36],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Sun Yat-sen University Cancer Center","RECRUITING","Guangzhou","Guangdong","510000","China","CN",{"type":45,"coordinates":46},"Point",[47,48],113.25,23.11667,{"lat":48,"lon":47},[51],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},{"type":53,"investigatorFullName":31,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Specialist Nurse","100637233","effects-of-different-tunnel-methods-in-picc-catheterization-100637233",false,"NCT07594704","Effects of Different Tunnel Methods in PICC Catheterization","Effects of Different Tunnel Methods in PICC Catheterization: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Aged between 18 and 75 years old;\n* Educational level of primary school or above, with basic listening, speaking, reading and writing abilities, and capable of completing the questionnaire independently;\n* Receiving tunneled PICC catheterization for the first time, with 4Fr single-lumen solo PICC catheter indwelling;\n* Able to attend regular PICC maintenance at our hospital as scheduled after catheterization;\n* Voluntarily participate in this study and sign the informed consent form for this study as well as the informed consent form for PICC catheterization.\n\nExclusion Criteria:\n\n* Patients with coagulation dysfunction (INR \\> 1.5 \u002F PLT \\\u003C 50×10⁹\u002FL);\n* Pregnant or lactating women;\n* Patients with BMI \\\u003C 18.5 kg\u002Fm²;\n* Patients receiving PICC catheterization via lower extremity veins;\n* Patients with known or suspected allergy to components of PICC catheters.","ALL","18 Years","75 Years",{"count":66,"type":67},284,"ESTIMATED","INTERVENTIONAL",[70],"NA","This prospective randomized controlled trial compares the effectiveness and safety of one-needle and two-needle tunneling techniques for peripherally inserted central catheter (PICC) placement, aiming to identify the optimal tunneling method to reduce catheter-related complications.",[73,74],"PICC Line Placement","PICC-associated Thrombosis",[76,77,78,79,80,81],"tunnel","PICC","complications","thrombosis","infection","bleeding","2026-05-18",{"date":84,"type":85},"2026-05-22","ACTUAL",{"date":87,"type":85},"2026-04-01",{"date":89,"type":67},"2026-07-30",{"name":5,"class":6},1]