[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100385533":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":40,"responsibleParty":66,"collaborators":26,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":26,"eligibilityCriteria":76,"healthyVolunteers":72,"sex":77,"minAge":78,"maxAge":26,"enrollmentInfo":79,"targetDuration":26,"studyType":82,"phases":83,"briefSummary":85,"conditions":86,"keywords":88,"overallStatus":43,"whyStopped":26,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"University of British Columbia","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Dietary nitrate supplementation","EXPERIMENTAL","The dietary nitrate supplement will be a concentrated, nitrate-rich beetroot juice (70 ml providing ∼400mg nitrate per serving)",[13],"Dietary Supplement: concentrated beetroot juice (400mg of nitrate per serving)",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo","PLACEBO_COMPARATOR","The placebo will be a concentrated, nitrate-depleted beetroot juice (70 ml with trace amounts of nitrate)",[19],"Dietary Supplement: concentrated beetroot juice (trace amounts of nitrate per serving)",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DIETARY_SUPPLEMENT","concentrated beetroot juice (400mg of nitrate per serving)","Dietary nitrate supplementation includes consumption of two beverages daily for 7 consecutive days.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"concentrated beetroot juice (trace amounts of nitrate per serving)","Dietary placebo supplementation includes consumption of two beverages daily for 7 consecutive days.",[15],[32,37],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Olivia Ferguson, MSc","CONTACT","604-806-8835","Olivia.Ferguson@hli.ubc.ca",{"name":38,"role":34,"phone":35,"phoneExt":26,"email":39},"Dhillon Satvir, MSc","satvir.dhillon@hli.ubc.ca",[41,60],{"facility":42,"status":43,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"Providence Health Care - St. Paul's Hosptial","RECRUITING","Vancouver","British Columbia","V6Z 1Y6","Canada","CA",{"type":50,"coordinates":51},"Point",[52,53],-123.11934,49.24966,{"lat":53,"lon":52},[56],{"name":57,"role":34,"phone":58,"phoneExt":26,"email":59},"Jordan Guenette, Ph.D","604-682-2344","jordan.guenette@hli.ubc.ca",{"facility":61,"status":43,"city":44,"state":26,"zip":62,"country":47,"countryCode":48,"cosmosGeoPoint":63,"geoPoint":65,"contacts":26},"Vancouver Coastal Health","V5Z 1M9",{"type":50,"coordinates":64},[52,53],{"lat":53,"lon":52},{"type":67,"investigatorFullName":68,"investigatorTitle":69,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Jordan Guenette","Director of Cardiopulmonary Exercise Physiology Laboratory","100385533","effects-of-drinking-beetroot-juice-on-exercise-performance-in-patients-with-fibrotic-interstitial-lung-disease-100385533",false,"NCT04299945","Effects of Drinking Beetroot Juice on Exercise Performance in Patients With Fibrotic Interstitial Lung Disease","The Effects of Dietary Nitrate Supplementation on Exercise Tolerance in Patients With Fibrotic Interstitial Lung Disease","Inclusion Criteria:\n\n* A multidisciplinary diagnosis of idiopathic pulmonary fibrosis (IPF), idiopathic fibrotic nonspecific interstitial pneumonia (NSIP), chronic hypersensitivity pneumonitis (HP), or unclassifiable ILD with a differential diagnosis that consists of the above diagnoses\n* Fibrosis on high resolution computed tomography (HRCT): honeycombing, reticulation, or traction bronchiectasis\n* Oxygen saturation ≥92% by pulse oximetry at rest while breathing room air\n* Clinically stable for the preceding 6 weeks\n* Can fluently read and write in English\n\nExclusion Criteria:\n\n* Contraindication to exercise testing (e.g. significant cardiovascular, musculoskeletal, neurological disease) (see Table 4 from ERS\u002FATS consensus statement)\n* Other significant pulmonary or extra-pulmonary disease that, based on clinical assessment, could impair exercise capacity and\u002For oxygenation\n* FVC \\\u003C50% or DLCO \\\u003C25%\n* Use of prednisone \\>10 mg\u002Fday for \\>2 weeks within 3 months of the first study visit\n* Cardiac pacemaker or any metal or electronics inside of the body","ALL","19 Years",{"count":80,"type":81},15,"ESTIMATED","INTERVENTIONAL",[84],"NA","Exercise training as part of a structured pulmonary rehabilitation program is a key factor in improving quality of life and symptoms in people with interstitial lung disease (ILD). Optimal methods of exercise training are yet to be explored in ILD. Drinking beetroot juice, which is rich in nitrate, has been shown to improve exercise performance in a variety of groups, but its effects in ILD have not been tested. The purpose of this study is to determine if drinking nitrate-rich beetroot juice can improve exercise performance compared to drinking nitrate-free beetroot juice in people with ILD.",[87],"Interstitial Lung Disease",[89,90,91,92],"ILD","Nitrates","exercise","interstitial lung disease","2026-05-13",{"date":95,"type":96},"2026-05-18","ACTUAL",{"date":98,"type":96},"2024-08-07",{"date":100,"type":81},"2026-12-31",{"name":5,"class":6},2]