[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100571111":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":26,"locations":33,"responsibleParty":51,"collaborators":53,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":25,"eligibilityCriteria":63,"healthyVolunteers":64,"sex":65,"minAge":66,"maxAge":25,"enrollmentInfo":67,"targetDuration":25,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":78,"overallStatus":36,"whyStopped":25,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Chang Gung Memorial Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"endogenous gamma light","ACTIVE_COMPARATOR","This device is an LED light source table lamp with a vertical surface measuring 16 cm by 22 cm. It will be positioned within arm's reach, approximately 50 cm from the participant, to ensure continuous exposure to the light stimulation. The active device delivers endogenous gamma light stimulation.",[13],"Device: Gamma Wave Stimulation Table Lamp (Aleddra, Inc., USA)",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham (70Hz) gamma light","SHAM_COMPARATOR","The sham device is identical in appearance to the active device. It will be positioned within arm's reach, approximately 50 cm from the participant, to ensure continuous exposure to the light stimulation. The sham device delivers 70 Hz light stimulation.",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","Gamma Wave Stimulation Table Lamp (Aleddra, Inc., USA)","Participants will receive light stimulation using the Gamma Wave Stimulation Table Lamp (Aleddra, Inc., USA) for 1 hour per day, 7 days a week, over 4 weeks, for a total of 28 hours.",[15,9],null,[27],{"name":28,"role":29,"phone":30,"phoneExt":31,"email":32},"Chia-Hsiung Cheng, Ph.D.","CONTACT","+886-3-211800","3854","ch.cheng@mail.cgu.edu.tw",[34],{"facility":35,"status":36,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Chang Gung University","RECRUITING","Taoyuan","Guishan","33302","Taiwan","TW",{"type":43,"coordinates":44},"Point",[45,46],121.29696,24.99368,{"lat":46,"lon":45},[49,50],{"name":28,"role":29,"phone":30,"phoneExt":31,"email":32},{"name":28,"role":29,"phone":25,"phoneExt":25,"email":25},{"type":52,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[54],{"name":55,"class":56},"Aleddra, Inc.","INDUSTRY","100571111","effects-of-endogenous-gamma-light-stimulation-on-brain-oscillations-in-cognitively-normal-older-adults-100571111",false,"NCT06715995","Effects of Endogenous Gamma Light Stimulation on Brain Oscillations in Cognitively-normal Older Adults","Effects of Endogenous Gamma Light Stimulation on Brain Oscillations in Cognitively-normal Older Adults: a Randomized, Placebo-controlled, Double-blind Study","Inclusion Criteria:\n\n* 1\\. Age over 55 years old.\n* 2\\. The Cognitive Abilities Screening Instrument (CASI) score is within normal ranges adjusted for age and education.\n* 3\\. Participants have no history of severe neurological or psychiatric disorders (such as stroke, epilepsy, depression, migraine, etc.) that could affect cognitive function.\n* 4\\. Participants have not used drugs that may affect cognitive function (e.g., benzodiazepines, anticholinergic medications, etc.).\n* 5\\. Participants with normal or corrected vision (e.g., glasses or contact lenses) to normal levels.\n* 6\\. Voluntary to sign the Informed Consent Form.\n\nExclusion Criteria:\n\n* 1\\. Participants enrolled in any cognitive enhancement study within the past two months.\n* 2\\. Participants with a history of disease that could affect cognitive function (e.g., cancer, autoimmune diseases, etc.).\n* 3\\. Pregnant, or planning to become pregnant.",true,"ALL","55 Years",{"count":68,"type":69},52,"ESTIMATED","INTERVENTIONAL",[72],"NA","This study aims to evaluate the effects of endogenous gamma non-flickering light stimulation on resting-state EEG rhythms and cognitive function in cognitively healthy older adults. Specifically, it will assess the immediate and long-term effects of this stimulation on brainwave activity and cognitive performance. The study will explore the potential of gamma light stimulation as a non-pharmacological intervention for cognitive decline in aging populations.",[75,76,77],"EEG Brain Oscillations","Alzheimer's Disease (AD)","Cognitively Normal Older Adults",[79,80,81,82,83,84],"Endogenous gamma","EEG rhythms","Resting-state EEG (rs-EEG)","Alzheimer's disease (AD)","Cognitive function","non-flickering light","2024-11-28",{"date":87,"type":88},"2024-12-04","ACTUAL",{"date":90,"type":69},"2024-12-09",{"date":92,"type":69},"2025-09-30",{"name":5,"class":6},1]