[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100597476":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":40,"centralContacts":44,"locations":54,"responsibleParty":70,"collaborators":48,"id":72,"slug":73,"hasResults":74,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":78,"eligibilityCriteria":79,"healthyVolunteers":74,"sex":80,"minAge":81,"maxAge":82,"enrollmentInfo":83,"targetDuration":48,"studyType":86,"phases":87,"briefSummary":89,"conditions":90,"keywords":93,"overallStatus":96,"whyStopped":48,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":106},{"fullName":5,"class":6},"Lanzhou University Second Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"EECP + Cardiac Rehabilitation","EXPERIMENTAL","Participants will receive enhanced external counterpulsation (EECP) plus a structured cardiac rehabilitation program that includes individualized aerobic exercise training, health education, psychological support and lifestyle counselling.",[13],"Behavioral: Cardiac Rehabilitation Combined With EECP",{"label":15,"type":16,"description":17,"interventionNames":18},"Routine Medical Care","ACTIVE_COMPARATOR","Participants will continue to receive standard pharmacologic management and routine clinical follow-up for atrial fibrillation without EECP or formal cardiac rehabilitation.",[19],"Other: Routine Medical Care",[21,33],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Cardiac Rehabilitation Combined With EECP","This intervention consists of a comprehensive cardiac rehabilitation program that includes individualized aerobic exercise training, health education, psychological support, and lifestyle counseling, combined with enhanced external counterpulsation (EECP) therapy administered according to standard cardiovascular protocols. The combined intervention is designed to improve cardiac function, exercise tolerance, and quality of life in patients with atrial fibrillation.",[9],[27,28,29,30,31,32],"Enhanced External Counterpulsation","EECP","Cardiac Rehabilitation","CR","Lifestyle Modification","Exercise Training",{"type":6,"name":15,"description":34,"armGroupLabels":35,"otherNames":36},"Participants in the control group will receive standard medical treatment for atrial fibrillation as prescribed by their attending physicians, without enhanced external counterpulsation or structured cardiac rehabilitation. This may include pharmacological therapy, routine clinical monitoring, and general lifestyle advice.",[15],[37,38,39],"Standard Care","Usual Care","Pharmacological Management",[41],{"name":42,"affiliation":5,"role":43},"Xiaowei Zhang PhD","PRINCIPAL_INVESTIGATOR",[45,50],{"name":42,"role":46,"phone":47,"phoneExt":48,"email":49},"CONTACT","17701272944",null,"yanxiwenny@foxmail.com",{"name":51,"role":46,"phone":52,"phoneExt":48,"email":53},"Yixin Xie","+86 18624069446","xieyixintaoyao@outlook.com",[55],{"facility":5,"status":48,"city":56,"state":57,"zip":58,"country":59,"countryCode":60,"cosmosGeoPoint":61,"geoPoint":66,"contacts":67},"Lanzhou","Gansu","730030","China","CN",{"type":62,"coordinates":63},"Point",[64,65],103.83987,36.05701,{"lat":65,"lon":64},[68],{"name":69,"role":46,"phone":47,"phoneExt":48,"email":49},"Xiaowei Zhang",{"type":43,"investigatorFullName":69,"investigatorTitle":71,"investigatorAffiliation":5,"oldNameTitle":48,"oldOrganization":48},"lanzhou university second hospital","100597476","effects-of-enhanced-external-counterpulsation-combined-with-cardiac-rehabilitation-in-patients-with-atrial-fibrillation-100597476",false,"NCT07058987","Effects of Enhanced External Counterpulsation Combined With Cardiac Rehabilitation in Patients With Atrial Fibrillation","A Prospective Randomized Controlled Study on the Effects of Enhanced External Counterpulsation Combined With Cardiac Rehabilitation on Cardiac Function and Exercise Capacity in Patients With Atrial Fibrillation","EECP AF CR","Inclusion Criteria:\n\n* Age between 40 and 80 years\n* Diagnosed with persistent or paroxysmal atrial fibrillation, confirmed by ECG or Holter\n* Stable medical condition and able to participate in cardiac rehabilitation and EECP therapy\n* Provided written informed consent\n\nExclusion Criteria:\n\n* Recent acute myocardial infarction, unstable angina, or decompensated heart failure within the past 4 weeks\n* Severe valvular heart disease or left ventricular ejection fraction \\\u003C30%\n* Severe peripheral vascular disease or deep vein thrombosis\n* Severe pulmonary disease or active infection\n* History of bleeding disorders or contraindications to EECP\n* Cognitive impairment or psychiatric condition affecting study participation\n* Participation in another clinical trial within the past 3 months","ALL","40 Years","80 Years",{"count":84,"type":85},200,"ESTIMATED","INTERVENTIONAL",[88],"NA","This is a prospective randomized controlled trial designed to evaluate the effectiveness of enhanced external counterpulsation (EECP) combined with cardiac rehabilitation in patients with atrial fibrillation. The study aims to assess whether this combined intervention can improve cardiac function and exercise capacity compared to standard care alone. Eligible participants will be randomly assigned to receive either the EECP plus cardiac rehabilitation program or routine treatment. Primary outcomes include changes in left ventricular ejection fraction (LVEF) and six-minute walking distance (6MWD). The study will be conducted at Lanzhou University Second Hospital.",[91,92,29],"Atrial Fibrillation (AF)","Heart Failure (HF)",[94,29,27,95],"Atrial Fibrillation","Exercise Capacity","NOT_YET_RECRUITING","2025-07-09",{"date":99,"type":100},"2025-07-14","ACTUAL",{"date":102,"type":85},"2025-07-15",{"date":104,"type":85},"2026-03",{"name":5,"class":6},1]