[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100628804":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":40,"responsibleParty":53,"collaborators":55,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":66,"eligibilityCriteria":67,"healthyVolunteers":62,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":25,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":80,"overallStatus":88,"whyStopped":25,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"Universidad Complutense de Madrid","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"HMB Supplement + Rehabilitation Program","EXPERIMENTAL","Participants receive beta-hydroxy-beta-methylbutyrate (HMB) supplementation in combination with a rehabilitation program consisting of eccentric exercise and extracorporeal shock wave therapy.",[13,14],"Other: Eccentric exercise and extracorporeal shock wave therapy","Dietary Supplement: Beta-hydroxy-beta-methylbutyrate (HMB)",{"label":16,"type":17,"description":18,"interventionNames":19},"Placebo + Rehabilitation Program","PLACEBO_COMPARATOR","Participants receive placebo supplementation in combination with a rehabilitation program consisting of eccentric exercise and extracorporeal shock wave therapy.",[13],[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Eccentric exercise and extracorporeal shock wave therapy","Participants undergo a standardized rehabilitation program consisting of eccentric exercise and extracorporeal shock wave therapy.",[9,16],null,{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":25},"DIETARY_SUPPLEMENT","Beta-hydroxy-beta-methylbutyrate (HMB)","Participants ingest 3 g\u002Fday of beta-hydroxy-beta-methylbutyrate (HMB) in capsule form, administered 60 minutes before each eccentric training session during the 8-week intervention period.",[9],[32],{"name":33,"affiliation":5,"role":34},"Juan J Ramos-Álvarez, MD","PRINCIPAL_INVESTIGATOR",[36],{"name":33,"role":37,"phone":38,"phoneExt":25,"email":39},"CONTACT","+34 913941367","jjramosa@ucm.es",[41],{"facility":42,"status":25,"city":43,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":25},"Clínica Fisio-Agil","Córdoba","14007","Spain","ES",{"type":48,"coordinates":49},"Point",[50,51],-4.77275,37.89155,{"lat":51,"lon":50},{"type":54,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[56,58],{"name":57,"class":6},"Universidad de Córdoba",{"name":59,"class":6},"University of Seville","100628804","effects-of-hmb-and-rehabilitation-program-in-athletes-with-patellar-tendinopathy-100628804",false,"NCT07466407","Effects of HMB and Rehabilitation Program in Athletes With Patellar Tendinopathy","Effects of Beta-Hydroxy-Beta-Methylbutyrate (HMB) Supplementation in Athletes With Patellar Tendinopathy","HMB_TEN","Inclusion Criteria:\n\n* Age between 18 and 49 years\n* Clinical diagnosis of patellar tendinopathy confirmed by a physician and physiotherapist\n* Competitive athlete in sports involving repetitive knee loading (e.g., basketball, volleyball, handball, athletics)\n* Minimum training frequency of three sessions per week\n* No knee surgery within the previous 12 months\n* No nutritional supplementation within the previous 3 months\n* No injection therapy (analgesics or platelet-rich plasma) within the previous 12 months\n* Non-smoker\n* Signed informed consent\n\nExclusion Criteria:\n\n* Any musculoskeletal injury other than patellar tendinopathy affecting performance\n* Systemic disease affecting musculoskeletal function\n* Inability to comply with the rehabilitation or supplementation protocol","ALL","18 Years","49 Years",{"count":72,"type":73},30,"ESTIMATED","INTERVENTIONAL",[76],"NA","This randomized, double-blind, placebo-controlled clinical trial evaluates the effects of oral beta-hydroxy-beta-methylbutyrate (HMB) supplementation combined with an eccentric exercise and extracorporeal shockwave rehabilitation program on pain, tendon morphology, and neuromuscular performance in athletes with patellar tendinopathy.\n\nThirty athletes with a confirmed diagnosis of patellar tendinopathy are randomized to receive either HMB supplementation (3 g\u002Fday) or placebo during an 8-week rehabilitation program. Participants are evaluated at baseline, week 4, and week 8.\n\nThe primary outcome is pain and functional limitation assessed using the Victorian Institute of Sport Assessment-Patella (VISA-P) questionnaire. Secondary outcomes include patellar tendon thickness measured by ultrasound imaging, countermovement jump (CMJ) performance, and neuromuscular performance variables derived from an incremental squat test using a linear position transducer.\n\nThe aim of the study is to determine whether HMB supplementation enhances clinical recovery and neuromuscular performance when combined with a standardized rehabilitation program compared with placebo.",[79],"Patellar Tendinopathy",[81,82,83,84,85,86,87],"Tendinopathy","HMB","Rehabilitation","Knee pain","Sports injury","Nutritional supplement","Beta-hydroxy-beta-methylbutyrate","NOT_YET_RECRUITING","2026-03-09",{"date":91,"type":92},"2026-03-12","ACTUAL",{"date":94,"type":73},"2026-03-01",{"date":96,"type":73},"2026-07-01",{"name":5,"class":6},1]