[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100565278":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":31,"centralContacts":44,"locations":54,"responsibleParty":71,"collaborators":31,"id":75,"slug":76,"hasResults":77,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":31,"eligibilityCriteria":81,"healthyVolunteers":77,"sex":82,"minAge":83,"maxAge":84,"enrollmentInfo":85,"targetDuration":31,"studyType":88,"phases":89,"briefSummary":91,"conditions":92,"keywords":94,"overallStatus":57,"whyStopped":31,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":110},{"fullName":5,"class":6},"Hong Kong Metropolitan University","OTHER",[8,15,21],{"label":9,"type":10,"description":11,"interventionNames":12},"Group A (sham IMT- stable group)","SHAM_COMPARATOR","conventional treatment + sham IMT",[13,14],"Other: sham IMT","Other: Conventional treatment",{"label":16,"type":17,"description":18,"interventionNames":19},"Group B (IMT-stable group)","EXPERIMENTAL","conventional treatment + target IMT while sitting on a stable surface",[20,14],"Other: IMT-stable group (sitting on a stable surface)",{"label":22,"type":17,"description":23,"interventionNames":24},"Group C (IMT-unstable group)","conventional treatment + target IMT while sitting on an unstable surface",[25,14],"Other: IMT-unstable group (sitting on an unstable surface)",[27,32,36,40],{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"sham IMT","with 10% maximum inspiratory pressure (MIP) as the training intensity, IMT will be conducted on a stable surface",[9],null,{"type":6,"name":33,"description":34,"armGroupLabels":35,"otherNames":31},"IMT-stable group (sitting on a stable surface)","50% MIP as the training intensity, IMT will be conducted while sitting on a stable surface",[16],{"type":6,"name":37,"description":38,"armGroupLabels":39,"otherNames":31},"IMT-unstable group (sitting on an unstable surface)","50% MIP as the training intensity, IMT will be conducted while sitting on an unstable surface",[22],{"type":6,"name":41,"description":42,"armGroupLabels":43,"otherNames":31},"Conventional treatment","Participants in all groups will receive a standardised conventional rehabilitation protocol. It includes limb range of motion, muscle tone reduction, strengthening and endurance of limb muscles, transfer skills, task-directed movements, general gait training, and activities of daily living training.",[9,16,22],[45,50],{"name":46,"role":47,"phone":48,"phoneExt":31,"email":49},"Fang LIU","CONTACT","+86 13603049475","s1350035@live.hkmu.edu.hk",{"name":51,"role":47,"phone":52,"phoneExt":31,"email":53},"William Wai-nam Tsang","085239708703","wntsang@hkmu.edu.hk",[55],{"facility":56,"status":57,"city":58,"state":59,"zip":31,"country":60,"countryCode":61,"cosmosGeoPoint":62,"geoPoint":67,"contacts":68},"Shenzhen Second People's Hospital","RECRUITING","Shenzhen","None Selected","China","CN",{"type":63,"coordinates":64},"Point",[65,66],114.0683,22.54554,{"lat":66,"lon":65},[69],{"name":46,"role":47,"phone":70,"phoneExt":31,"email":49},"+8613603049475",{"type":72,"investigatorFullName":73,"investigatorTitle":74,"investigatorAffiliation":5,"oldNameTitle":31,"oldOrganization":31},"PRINCIPAL_INVESTIGATOR","LIU FANG","Principal Investigator","100565278","effects-of-inspiratory-muscle-training-on-stroke-rehabilitation-outcomes-100565278",false,"NCT06640101","Effects of Inspiratory Muscle Training on Stroke Rehabilitation Outcomes","Effect of Inspiratory Muscle Training on Respiratory Function, Diaphragm Thickness, Balance Control, Exercise Capacity and Quality of Life in People After Stroke: a Randomized Controlled Trial","Inclusion Criteria:\n\n* Age ≥ 40 years and \\\u003C 80 years;\n* breathing spontaneously;\n* clinically diagnosed with ischemic and\u002For haemorrhagic stroke;\n* duration of stroke from onset falls within 1 month to 12 months after diagnosis;\n* no thoracic or abdominal surgery within the last 6 months;\n* able to understand and follow verbal instructions;\n* no facial palsy, or mild facial palsy without limitation of labial occlusion;\n* able to maintain a resting sitting posture without feet support for at least 30 seconds;\n* no cognitive impairment (Montreal Cognitive Assessment (MoCA) score ≥ 26);\n* able to independently walk at least 10 meters with or without an assistive device.\n\nExclusion Criteria:\n\n* acute myocardial infarction or acute heart failure;\n* acute pain in any part of the body;\n* with respiratory illness or positive clinical signs of impaired respiratory function (such as shortness of breath, hypoxemia, chronic cough and sputum retention);\n* with chronic cardiovascular dysfunction;\n* Trunk Impairment Scale (TIS) score ≥ 20.\n* patient with a nasal feeding tube, tracheal tube and\u002For any condition that prevents the measurement or the implementation of the study procedure.","ALL","40 Years","80 Years",{"count":86,"type":87},84,"ESTIMATED","INTERVENTIONAL",[90],"NA","This study is designed to explore the effects of a 4-week protocol of inspiratory muscle training (IMT) at 50% maximum inspiratory pressure (MIP) on respiratory function, diaphragm thickness, balance control, exercise capacity, and quality of life in people after stroke. To ascertain the effect of IMT on the relationship between diaphragm muscle contraction and activation of other trunk muscles, this study also explores whether any effect of the 4-week IMT protocol on balance control is associated with changes in the anticipatory posture adjustments (APAs) time - the onset time of postural muscles during a required task (e.g., the rapid shoulder flexion test).",[93],"Stroke",[93,95,96,97,98,99,100],"Inspiratory muscle training","Diaphragm","Balance control","Exercise capacity","Quality of life","Anticipatory postural adjustment time","2025-02-20",{"date":103,"type":104},"2025-02-24","ACTUAL",{"date":106,"type":104},"2025-02-21",{"date":108,"type":87},"2026-06-15",{"name":5,"class":6},1]